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Modulation of thermal properties of bovine collagen scaffold using variation of fabrication template

It has been a major challenge in the creation of synthetic or natural materials to favour the regeneration of the damaged tissues and organs. The fabrication methods and techniques of the scaffold directly influence with physical, chemical, and biological function of the cells when a...

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Main Authors: Amerai Khan, Nur Amnatasha, Shahbuddin, Munira, Busra, Mohd Fauzi
Format: Article
Language:English
Published: IIUM Press 2023
Subjects:
TP Chemical technology
TP155 Chemical engineering
TP248.13 Biotechnology
Online Access:http://irep.iium.edu.my/106737/1/106737_Modulation%20of%20thermal%20properties.pdf
http://irep.iium.edu.my/106737/
https://journals.iium.edu.my/bnrej/index.php/bnrej/article/view/83
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spelling my.iium.irep.1067372023-12-21T01:34:44Z http://irep.iium.edu.my/106737/ Modulation of thermal properties of bovine collagen scaffold using variation of fabrication template Amerai Khan, Nur Amnatasha Shahbuddin, Munira Busra, Mohd Fauzi TP Chemical technology TP155 Chemical engineering TP248.13 Biotechnology It has been a major challenge in the creation of synthetic or natural materials to favour the regeneration of the damaged tissues and organs. The fabrication methods and techniques of the scaffold directly influence with physical, chemical, and biological function of the cells when applied in in vivo and in vitro. Design of scaffolds for tissue regeneration requires an intimate knowledge of precise relationships between structure and biological function. These scaffolds can have a broad range of morphological properties, such as interconnecting (open pores), non-connecting (closed pores), or a combination of both. The physicochemical structure of collagen scaffold influences the repairing and tissue building to take place without contraction and scar formation. The goal of the current study is to study the relation of volume and area of exposure to freeze-drying process using different sizes of aluminium tray to achieve different thermophysical properties of collagen scaffolds. Freeze-drying of collagen scaffold is useful because the production of a glassy amorphous material with a Tg above room temperature (>32 oC) makes the scaffold stable and can be stored on the shelf. From this endeavor, we hypothesized that dimension of fabrication template and volume are able to influence thermal properties of collagen scaffold’s glass transition temperature (Tg). IIUM Press 2023-07-26 Article PeerReviewed application/pdf en http://irep.iium.edu.my/106737/1/106737_Modulation%20of%20thermal%20properties.pdf Amerai Khan, Nur Amnatasha and Shahbuddin, Munira and Busra, Mohd Fauzi (2023) Modulation of thermal properties of bovine collagen scaffold using variation of fabrication template. Biological and Natural Resources Engineering Journal, 7 (1). pp. 35-42. E-ISSN 2637-0719 https://journals.iium.edu.my/bnrej/index.php/bnrej/article/view/83
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic TP Chemical technology
TP155 Chemical engineering
TP248.13 Biotechnology
spellingShingle TP Chemical technology
TP155 Chemical engineering
TP248.13 Biotechnology
Amerai Khan, Nur Amnatasha
Shahbuddin, Munira
Busra, Mohd Fauzi
Modulation of thermal properties of bovine collagen scaffold using variation of fabrication template
description It has been a major challenge in the creation of synthetic or natural materials to favour the regeneration of the damaged tissues and organs. The fabrication methods and techniques of the scaffold directly influence with physical, chemical, and biological function of the cells when applied in in vivo and in vitro. Design of scaffolds for tissue regeneration requires an intimate knowledge of precise relationships between structure and biological function. These scaffolds can have a broad range of morphological properties, such as interconnecting (open pores), non-connecting (closed pores), or a combination of both. The physicochemical structure of collagen scaffold influences the repairing and tissue building to take place without contraction and scar formation. The goal of the current study is to study the relation of volume and area of exposure to freeze-drying process using different sizes of aluminium tray to achieve different thermophysical properties of collagen scaffolds. Freeze-drying of collagen scaffold is useful because the production of a glassy amorphous material with a Tg above room temperature (>32 oC) makes the scaffold stable and can be stored on the shelf. From this endeavor, we hypothesized that dimension of fabrication template and volume are able to influence thermal properties of collagen scaffold’s glass transition temperature (Tg).
format Article
author Amerai Khan, Nur Amnatasha
Shahbuddin, Munira
Busra, Mohd Fauzi
author_facet Amerai Khan, Nur Amnatasha
Shahbuddin, Munira
Busra, Mohd Fauzi
author_sort Amerai Khan, Nur Amnatasha
title Modulation of thermal properties of bovine collagen scaffold using variation of fabrication template
title_short Modulation of thermal properties of bovine collagen scaffold using variation of fabrication template
title_full Modulation of thermal properties of bovine collagen scaffold using variation of fabrication template
title_fullStr Modulation of thermal properties of bovine collagen scaffold using variation of fabrication template
title_full_unstemmed Modulation of thermal properties of bovine collagen scaffold using variation of fabrication template
title_sort modulation of thermal properties of bovine collagen scaffold using variation of fabrication template
publisher IIUM Press
publishDate 2023
url http://irep.iium.edu.my/106737/1/106737_Modulation%20of%20thermal%20properties.pdf
http://irep.iium.edu.my/106737/
https://journals.iium.edu.my/bnrej/index.php/bnrej/article/view/83
_version_ 1787131878123241472
score 13.211869

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