Exophiala dermatitidis, ‘the real black fungus’ fungemia in a patient with COVID-19
The second wave of the COVID-19 pandemic in India had brought with it a surge of ‘black fungus’ co- infection, which is a misnomer for mucormycosis. The present case illustrates the ‘real black fungus’ infection in a 50-year old male patient with COVID-19 pneumonia, who otherwise had no significant...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Elsevier Ltd.
2022
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/105824/7/105824_Exophiala%20dermatitidis.pdf http://irep.iium.edu.my/105824/8/105824_Exophiala%20dermatitidis_Scopus.pdf http://irep.iium.edu.my/105824/ https://www.sciencedirect.com/science/article/pii/S2214250922000567?via%3Dihub |
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| Summary: | The second wave of the COVID-19 pandemic in India had brought with it a surge of ‘black fungus’ co- infection, which is a misnomer for mucormycosis. The present case illustrates the ‘real black fungus’ infection in a 50-year old male patient with COVID-19 pneumonia, who otherwise had no significant previous medical history. He was admitted on day 8 of COVID-19 illness and was intubated due to persistently low oxygen saturation. Blood cultures were positive for flask-shaped dematiaceous budding yeasts with pseudohyphae formation, which grew as brown-black fuzzy colonies on Sabouraud dextrose agar. The isolate was identified as Exophiala dermatitidis based on phenotypic characterization. Despite antifungal therapy with amphotericin B and itraconazole, the patient deteriorated rapidly and succumbed to acute respiratory distress syndrome and multiorgan failure. A review of reported cases of Exophiala dermatitidis fungemia over the last 5-years is discussed. |
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