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Systems thinking approach on foetal abnormalities associated with alpha-fetoprotein level

Foetal complications associated with abnormal Alpha-Fetoprotein (AFP) levels are becoming a serious matter. The risk of adverse pregnancy outcomes (APOs) is substantially greater in the raised maternal serum-alpha fetoprotein (MS-AFP) group than in the normal MS-AFP group. The top three APOs in term...

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Main Authors: Mohd Nong, Nur Sakinah, Shogar, Ibrahim Adam Ahmed, Abdul Rahman, Suzanah
Format: Article
Language:English
English
Published: Kulliyyah of Medicine, International Islamic University Malaysia 2023
Subjects:
R Medicine (General)
Online Access:http://irep.iium.edu.my/104388/2/104388_Systems%20thinking%20approach%20on%20Foetal%20abnormalities%20associate.pdf
http://irep.iium.edu.my/104388/8/104388_Systems%20Thinking%20Approach%20on%20Foetal%20Abnormalities%20Associated_Scopus.pdf
http://irep.iium.edu.my/104388/
https://journals.iium.edu.my/kom/index.php/imjm/article/view/2163
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spelling my.iium.irep.1043882024-01-24T09:03:20Z http://irep.iium.edu.my/104388/ Systems thinking approach on foetal abnormalities associated with alpha-fetoprotein level Mohd Nong, Nur Sakinah Shogar, Ibrahim Adam Ahmed Abdul Rahman, Suzanah R Medicine (General) Foetal complications associated with abnormal Alpha-Fetoprotein (AFP) levels are becoming a serious matter. The risk of adverse pregnancy outcomes (APOs) is substantially greater in the raised maternal serum-alpha fetoprotein (MS-AFP) group than in the normal MS-AFP group. The top three APOs in terms of occurrence rate in the increased MS-AFP group were structural foetal abnormalities, spontaneous abortion, and premature delivery. Low levels of AFP in the maternal may indicate a risk of Down syndrome (DS). This is an important matter that needs to be investigated and dealt with promptly. This research aims to investigate methods of diagnosis and screening on AFP foetal based on system thinking. It applies the systems thinking approach on foetal complications associated with AFP level from a theoretical perspective. The purpose is to provide an analytical and integrated method to deal with foetal complications associated with AFP level. This integrated approach comprises various analytical aspects, including conceptual framework, data analysis, evaluation of the diagnostic and screening methods. How systems thinking can contribute to improving all these aspects of foetal complication will be investigated. A systematic review of literature from various databases was conducted. The methodology also enabled a detailed explanation of the major problems of AFP in the form of a causal loop diagram based on the holistic view of the systems thinking approach. This research is expected to contribute in various ways on how systems thinking can contribute to overcoming foetal abnormalities associated with abnormal AFP levels. It is expected that the application of a systems approach could provide an effective method of analysis for understanding and managing the foetal abnormalities by considering all aspects in a holistic manner and clearer methods of intervention to reduce the cases. Kulliyyah of Medicine, International Islamic University Malaysia 2023-04-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/104388/2/104388_Systems%20thinking%20approach%20on%20Foetal%20abnormalities%20associate.pdf application/pdf en http://irep.iium.edu.my/104388/8/104388_Systems%20Thinking%20Approach%20on%20Foetal%20Abnormalities%20Associated_Scopus.pdf Mohd Nong, Nur Sakinah and Shogar, Ibrahim Adam Ahmed and Abdul Rahman, Suzanah (2023) Systems thinking approach on foetal abnormalities associated with alpha-fetoprotein level. IIUM Medical Journal Malaysia, 22 (2). pp. 29-38. ISSN 1823-4631 E-ISSN 2735-2285 https://journals.iium.edu.my/kom/index.php/imjm/article/view/2163 10.31436/imjm.v22i2
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
English
topic R Medicine (General)
spellingShingle R Medicine (General)
Mohd Nong, Nur Sakinah
Shogar, Ibrahim Adam Ahmed
Abdul Rahman, Suzanah
Systems thinking approach on foetal abnormalities associated with alpha-fetoprotein level
description Foetal complications associated with abnormal Alpha-Fetoprotein (AFP) levels are becoming a serious matter. The risk of adverse pregnancy outcomes (APOs) is substantially greater in the raised maternal serum-alpha fetoprotein (MS-AFP) group than in the normal MS-AFP group. The top three APOs in terms of occurrence rate in the increased MS-AFP group were structural foetal abnormalities, spontaneous abortion, and premature delivery. Low levels of AFP in the maternal may indicate a risk of Down syndrome (DS). This is an important matter that needs to be investigated and dealt with promptly. This research aims to investigate methods of diagnosis and screening on AFP foetal based on system thinking. It applies the systems thinking approach on foetal complications associated with AFP level from a theoretical perspective. The purpose is to provide an analytical and integrated method to deal with foetal complications associated with AFP level. This integrated approach comprises various analytical aspects, including conceptual framework, data analysis, evaluation of the diagnostic and screening methods. How systems thinking can contribute to improving all these aspects of foetal complication will be investigated. A systematic review of literature from various databases was conducted. The methodology also enabled a detailed explanation of the major problems of AFP in the form of a causal loop diagram based on the holistic view of the systems thinking approach. This research is expected to contribute in various ways on how systems thinking can contribute to overcoming foetal abnormalities associated with abnormal AFP levels. It is expected that the application of a systems approach could provide an effective method of analysis for understanding and managing the foetal abnormalities by considering all aspects in a holistic manner and clearer methods of intervention to reduce the cases.
format Article
author Mohd Nong, Nur Sakinah
Shogar, Ibrahim Adam Ahmed
Abdul Rahman, Suzanah
author_facet Mohd Nong, Nur Sakinah
Shogar, Ibrahim Adam Ahmed
Abdul Rahman, Suzanah
author_sort Mohd Nong, Nur Sakinah
title Systems thinking approach on foetal abnormalities associated with alpha-fetoprotein level
title_short Systems thinking approach on foetal abnormalities associated with alpha-fetoprotein level
title_full Systems thinking approach on foetal abnormalities associated with alpha-fetoprotein level
title_fullStr Systems thinking approach on foetal abnormalities associated with alpha-fetoprotein level
title_full_unstemmed Systems thinking approach on foetal abnormalities associated with alpha-fetoprotein level
title_sort systems thinking approach on foetal abnormalities associated with alpha-fetoprotein level
publisher Kulliyyah of Medicine, International Islamic University Malaysia
publishDate 2023
url http://irep.iium.edu.my/104388/2/104388_Systems%20thinking%20approach%20on%20Foetal%20abnormalities%20associate.pdf
http://irep.iium.edu.my/104388/8/104388_Systems%20Thinking%20Approach%20on%20Foetal%20Abnormalities%20Associated_Scopus.pdf
http://irep.iium.edu.my/104388/
https://journals.iium.edu.my/kom/index.php/imjm/article/view/2163
_version_ 1789424007415595008
score 13.211869

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