Corrosion in Mg-alloy biomedical implants- the strategies to reduce the impact of the corrosion inflammatory reaction and microbial activity
The most common complication of orthopedic surgery is implant failure, which can result in catastrophic injury and a significant financial burden for patients. Implant failure can be caused by a variety of factors, the most common of which are peri–implant infection (or implantrelated infection), e...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Chinese Roots Global Impact (Science Direct)
2022
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/101678/1/101678_Corrosion%20in%20Mg-alloy%20biomedical%20implants.pdf http://irep.iium.edu.my/101678/ https://www.sciencedirect.com/science/article/pii/S2213956722002754 |
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| Summary: | The most common complication of orthopedic surgery is implant failure, which can result in catastrophic injury and a significant financial
burden for patients. Implant failure can be caused by a variety of factors, the most common of which are peri–implant infection (or implantrelated infection), excessive inflammatory response which caused pain and aseptic loosening. Orthopedic surgeons now have a variety of
options for treating these issues, including revision surgery, which has demonstrated to be effective. If excessive inflammatory reaction caused
by the corrosion and peri–implant infection can be avoided, it will be of enormous social benefits. This review will provide a summary of
corrosion and the inflammation reactions due to the corrosion and antimicrobial properties of Mg alloy-based implants covering both in vitro
and in vivo studies. The strategies on hindering/overcoming the excessive inflammatory response and enhancing the antimicrobial activity are
discussed in this review. |
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