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Development of Hydroxyapatite Carbon Modified Electrode (HAP-CME) for Drug Detection

Drug abuse is a global issue and it exist in both developed and developing countries. The conventional quantitative drug detection system has long detection time, complex operations, expensive, bulky, and not portable. Thus, an alternative, green in-situ detection system is needed. Voltammmetry hold...

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Main Author: Masing, Phil Foster
Format: Final Year Project
Published: Universiti Teknologi Petronas 2011
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TP Chemical technology
Online Access:http://utpedia.utp.edu.my/481/
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spelling my-utp-utpedia.4812017-01-19T15:45:15Z http://utpedia.utp.edu.my/481/ Development of Hydroxyapatite Carbon Modified Electrode (HAP-CME) for Drug Detection Masing, Phil Foster TP Chemical technology Drug abuse is a global issue and it exist in both developed and developing countries. The conventional quantitative drug detection system has long detection time, complex operations, expensive, bulky, and not portable. Thus, an alternative, green in-situ detection system is needed. Voltammmetry holds a great opportunity to be used as alternative for quantitative drug detection method due to its simplicity and accuracy. It has been reported that hydroxyapatite Carbon Modified Electrode (HAP-CME) has excellent electrocatalytical response and low detection limit in voltmammetry in the trace analysis of hazardous material. However, the usage HAP-CME in drug analysis has not been reported yet. In this paper, Ascorbic Acid (AA) is used as a drug. HAP-CME was fabricated by mixing Hydroxyapatite to the carbon paste mixture. As compared to the normal Carbon Paste Electrode (CPE), HAP-CME possesses good electrical conductivity, excellent sensitivity, and better electron transfer kinetics towards the standard redox couple of Fe(CN)63-/4- . Then, HAP-CME was further used for the detection AA and a successful result is obtained. HAP-CME exhibited an excellent electrocatalytical response towards the redox reaction of AA with lower detection limits and great sensitivity. Universiti Teknologi Petronas 2011-05 Final Year Project NonPeerReviewed Masing, Phil Foster (2011) Development of Hydroxyapatite Carbon Modified Electrode (HAP-CME) for Drug Detection. Universiti Teknologi Petronas, Sri Iskandar,Tronoh,Perak. (Unpublished)
institution Universiti Teknologi Petronas
building UTP Resource Centre
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Petronas
content_source UTP Electronic and Digitized Intellectual Asset
url_provider http://utpedia.utp.edu.my/
topic TP Chemical technology
spellingShingle TP Chemical technology
Masing, Phil Foster
Development of Hydroxyapatite Carbon Modified Electrode (HAP-CME) for Drug Detection
description Drug abuse is a global issue and it exist in both developed and developing countries. The conventional quantitative drug detection system has long detection time, complex operations, expensive, bulky, and not portable. Thus, an alternative, green in-situ detection system is needed. Voltammmetry holds a great opportunity to be used as alternative for quantitative drug detection method due to its simplicity and accuracy. It has been reported that hydroxyapatite Carbon Modified Electrode (HAP-CME) has excellent electrocatalytical response and low detection limit in voltmammetry in the trace analysis of hazardous material. However, the usage HAP-CME in drug analysis has not been reported yet. In this paper, Ascorbic Acid (AA) is used as a drug. HAP-CME was fabricated by mixing Hydroxyapatite to the carbon paste mixture. As compared to the normal Carbon Paste Electrode (CPE), HAP-CME possesses good electrical conductivity, excellent sensitivity, and better electron transfer kinetics towards the standard redox couple of Fe(CN)63-/4- . Then, HAP-CME was further used for the detection AA and a successful result is obtained. HAP-CME exhibited an excellent electrocatalytical response towards the redox reaction of AA with lower detection limits and great sensitivity.
format Final Year Project
author Masing, Phil Foster
author_facet Masing, Phil Foster
author_sort Masing, Phil Foster
title Development of Hydroxyapatite Carbon Modified Electrode (HAP-CME) for Drug Detection
title_short Development of Hydroxyapatite Carbon Modified Electrode (HAP-CME) for Drug Detection
title_full Development of Hydroxyapatite Carbon Modified Electrode (HAP-CME) for Drug Detection
title_fullStr Development of Hydroxyapatite Carbon Modified Electrode (HAP-CME) for Drug Detection
title_full_unstemmed Development of Hydroxyapatite Carbon Modified Electrode (HAP-CME) for Drug Detection
title_sort development of hydroxyapatite carbon modified electrode (hap-cme) for drug detection
publisher Universiti Teknologi Petronas
publishDate 2011
url http://utpedia.utp.edu.my/481/
_version_ 1739830664478326784
score 13.211869

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