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An Intelligent Detection System for Rheumatoid Arthritis (RA) Disease using Image Processing

Rheumatoid Arthritis (RA) is an autoimmune disease that causes chronic pain, stiffness, redness or loss of function in the joints. Other than early diagnosis, there is yet a cure available for RA. Diseases with similar symptoms such as lupus, osteoarthritis, gout cause difficulty in diagnosing RA. C...

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Main Author: Hajyyev, Abdyrahym
Format: Final Year Project
Language:English
Published: Universiti Teknologi PETRONAS 2014
Subjects:
TK Electrical engineering. Electronics Nuclear engineering
Online Access:http://utpedia.utp.edu.my/14231/1/Abdyrahym%20Hajyyev_12989_EE_Final%20Project%20%20Report.pdf
http://utpedia.utp.edu.my/14231/
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spelling my-utp-utpedia.142312017-01-25T09:37:14Z http://utpedia.utp.edu.my/14231/ An Intelligent Detection System for Rheumatoid Arthritis (RA) Disease using Image Processing Hajyyev, Abdyrahym TK Electrical engineering. Electronics Nuclear engineering Rheumatoid Arthritis (RA) is an autoimmune disease that causes chronic pain, stiffness, redness or loss of function in the joints. Other than early diagnosis, there is yet a cure available for RA. Diseases with similar symptoms such as lupus, osteoarthritis, gout cause difficulty in diagnosing RA. Currently, indirect immunofluorescence (IIF) test performed to identify ANA in Hep-2 cells. Thus, image processing techniques vital to make diagnosis more efficient, accurate and less time-consuming. For this project standardized staining pattern classifier to be designed by using image processing techniques. Current manual techniques has limited accuracy and time consuming. In IFF procedures, unsuitable microscope to read Hep-2 cell slides, or photo bleaching effect where cells bleached extremely in short period of time are disadvantages. Another downside is test results being subject to change with experts knowledge and years of experience. These factors lead to low accuracy and it becomes a lengthy process due to large number of images. Out of five types of staining patterns nucleolar and centromere share similar visual appearance and the same is true to homogeneous, fine-speckled, coarse-speckled patterns. This is one of the major factors affecting classification accuracy due to results being subjective. In this research, First and Second Order Statistics Feature Extraction, Mamdani Fuzzy Logic Classification methods utilized to develop automatic detection system for RA with the help of Matlab R2012b, Fuzzy Logic Toolbox, and Image Processing Toolbox. The algorithm tested on the publicly available Mivia Hep-2 Cell image dataset. Fuzzy logic classified 85 out of 250 images wrongly. It has 66% accuracy. The images obtained from MIVIA dataset has been manually segmented to cell level from the image level. Developing an automated segmentation algorithm might give better results. Universiti Teknologi PETRONAS 2014-05 Final Year Project NonPeerReviewed application/pdf en http://utpedia.utp.edu.my/14231/1/Abdyrahym%20Hajyyev_12989_EE_Final%20Project%20%20Report.pdf Hajyyev, Abdyrahym (2014) An Intelligent Detection System for Rheumatoid Arthritis (RA) Disease using Image Processing. Universiti Teknologi PETRONAS. (Unpublished)
institution Universiti Teknologi Petronas
building UTP Resource Centre
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Petronas
content_source UTP Electronic and Digitized Intellectual Asset
url_provider http://utpedia.utp.edu.my/
language English
topic TK Electrical engineering. Electronics Nuclear engineering
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Hajyyev, Abdyrahym
An Intelligent Detection System for Rheumatoid Arthritis (RA) Disease using Image Processing
description Rheumatoid Arthritis (RA) is an autoimmune disease that causes chronic pain, stiffness, redness or loss of function in the joints. Other than early diagnosis, there is yet a cure available for RA. Diseases with similar symptoms such as lupus, osteoarthritis, gout cause difficulty in diagnosing RA. Currently, indirect immunofluorescence (IIF) test performed to identify ANA in Hep-2 cells. Thus, image processing techniques vital to make diagnosis more efficient, accurate and less time-consuming. For this project standardized staining pattern classifier to be designed by using image processing techniques. Current manual techniques has limited accuracy and time consuming. In IFF procedures, unsuitable microscope to read Hep-2 cell slides, or photo bleaching effect where cells bleached extremely in short period of time are disadvantages. Another downside is test results being subject to change with experts knowledge and years of experience. These factors lead to low accuracy and it becomes a lengthy process due to large number of images. Out of five types of staining patterns nucleolar and centromere share similar visual appearance and the same is true to homogeneous, fine-speckled, coarse-speckled patterns. This is one of the major factors affecting classification accuracy due to results being subjective. In this research, First and Second Order Statistics Feature Extraction, Mamdani Fuzzy Logic Classification methods utilized to develop automatic detection system for RA with the help of Matlab R2012b, Fuzzy Logic Toolbox, and Image Processing Toolbox. The algorithm tested on the publicly available Mivia Hep-2 Cell image dataset. Fuzzy logic classified 85 out of 250 images wrongly. It has 66% accuracy. The images obtained from MIVIA dataset has been manually segmented to cell level from the image level. Developing an automated segmentation algorithm might give better results.
format Final Year Project
author Hajyyev, Abdyrahym
author_facet Hajyyev, Abdyrahym
author_sort Hajyyev, Abdyrahym
title An Intelligent Detection System for Rheumatoid Arthritis (RA) Disease using Image Processing
title_short An Intelligent Detection System for Rheumatoid Arthritis (RA) Disease using Image Processing
title_full An Intelligent Detection System for Rheumatoid Arthritis (RA) Disease using Image Processing
title_fullStr An Intelligent Detection System for Rheumatoid Arthritis (RA) Disease using Image Processing
title_full_unstemmed An Intelligent Detection System for Rheumatoid Arthritis (RA) Disease using Image Processing
title_sort intelligent detection system for rheumatoid arthritis (ra) disease using image processing
publisher Universiti Teknologi PETRONAS
publishDate 2014
url http://utpedia.utp.edu.my/14231/1/Abdyrahym%20Hajyyev_12989_EE_Final%20Project%20%20Report.pdf
http://utpedia.utp.edu.my/14231/
_version_ 1739831978242342912
score 13.211869

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