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MITOTIC HEP-2 CELL RECOGNIITON USING SUPPORT VECTOR MACHINE UNDER CLASS SKEW

A person with an autoimmune diseases will became hypersensitive to the surrounding that other normal person would usually not consider at all such as an allergy. This reaction happened when our immune system recognise our normal tissue as a dangerous foreign elements and proceed to attack them. The...

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Main Author: SHEIKH ABDUL KARIM, SITI YASMIN
Format: Final Year Project
Language:English
Published: Universiti Teknologi Petronas 2014
Subjects:
TK Electrical engineering. Electronics Nuclear engineering
Online Access:http://utpedia.utp.edu.my/13450/1/22.pdf
http://utpedia.utp.edu.my/13450/
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spelling my-utp-utpedia.134502017-01-25T09:38:07Z http://utpedia.utp.edu.my/13450/ MITOTIC HEP-2 CELL RECOGNIITON USING SUPPORT VECTOR MACHINE UNDER CLASS SKEW SHEIKH ABDUL KARIM, SITI YASMIN TK Electrical engineering. Electronics Nuclear engineering A person with an autoimmune diseases will became hypersensitive to the surrounding that other normal person would usually not consider at all such as an allergy. This reaction happened when our immune system recognise our normal tissue as a dangerous foreign elements and proceed to attack them. The presence of antinuclear autoantibodies (ANA) in a patient serum can be detected by using the Indirect Immunofluorescence (IIF) image. By adding the mitotic cells into the well, the level of accuracy of the results achieved can be increased. The mitotic cells itself plays a crucial role in diagnosing an autoimmune diseases. This paper will focuses on the extracting the features of a mitotic HEp-2 cell in order to determine the presence of an ANA by noting the cells fluorescent-stained pattern, their intensity and also the presence of the mitotic cell itself. A skewed distribution of both mitotic and non-mitotic cells in the samples will also be considered to ensure the practicality of the project. To assist in the objectives, all the techniques used are explain in more detailed in this paper along with the result obtained by simulation from MATLAB for every steps from pre-processing to user interface menu. The procedures for the recognition of mitotic cells are image acquisition, pre-processing, segmentation, feature extraction and classification. The results obtained were tested using HEp-2 cell image datasets from MIVIA and from collaboration with Hospital Universiti Sains Malaysia (HUSM). The feature extractor used is the gray level co-occurrence matrix (GLCM) and classified using support vector machine (SVM) which will be presented in the RESULTS section. Universiti Teknologi Petronas 2014-01 Final Year Project NonPeerReviewed application/pdf en http://utpedia.utp.edu.my/13450/1/22.pdf SHEIKH ABDUL KARIM, SITI YASMIN (2014) MITOTIC HEP-2 CELL RECOGNIITON USING SUPPORT VECTOR MACHINE UNDER CLASS SKEW. Universiti Teknologi Petronas. (Unpublished)
institution Universiti Teknologi Petronas
building UTP Resource Centre
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Petronas
content_source UTP Electronic and Digitized Intellectual Asset
url_provider http://utpedia.utp.edu.my/
language English
topic TK Electrical engineering. Electronics Nuclear engineering
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
SHEIKH ABDUL KARIM, SITI YASMIN
MITOTIC HEP-2 CELL RECOGNIITON USING SUPPORT VECTOR MACHINE UNDER CLASS SKEW
description A person with an autoimmune diseases will became hypersensitive to the surrounding that other normal person would usually not consider at all such as an allergy. This reaction happened when our immune system recognise our normal tissue as a dangerous foreign elements and proceed to attack them. The presence of antinuclear autoantibodies (ANA) in a patient serum can be detected by using the Indirect Immunofluorescence (IIF) image. By adding the mitotic cells into the well, the level of accuracy of the results achieved can be increased. The mitotic cells itself plays a crucial role in diagnosing an autoimmune diseases. This paper will focuses on the extracting the features of a mitotic HEp-2 cell in order to determine the presence of an ANA by noting the cells fluorescent-stained pattern, their intensity and also the presence of the mitotic cell itself. A skewed distribution of both mitotic and non-mitotic cells in the samples will also be considered to ensure the practicality of the project. To assist in the objectives, all the techniques used are explain in more detailed in this paper along with the result obtained by simulation from MATLAB for every steps from pre-processing to user interface menu. The procedures for the recognition of mitotic cells are image acquisition, pre-processing, segmentation, feature extraction and classification. The results obtained were tested using HEp-2 cell image datasets from MIVIA and from collaboration with Hospital Universiti Sains Malaysia (HUSM). The feature extractor used is the gray level co-occurrence matrix (GLCM) and classified using support vector machine (SVM) which will be presented in the RESULTS section.
format Final Year Project
author SHEIKH ABDUL KARIM, SITI YASMIN
author_facet SHEIKH ABDUL KARIM, SITI YASMIN
author_sort SHEIKH ABDUL KARIM, SITI YASMIN
title MITOTIC HEP-2 CELL RECOGNIITON USING SUPPORT VECTOR MACHINE UNDER CLASS SKEW
title_short MITOTIC HEP-2 CELL RECOGNIITON USING SUPPORT VECTOR MACHINE UNDER CLASS SKEW
title_full MITOTIC HEP-2 CELL RECOGNIITON USING SUPPORT VECTOR MACHINE UNDER CLASS SKEW
title_fullStr MITOTIC HEP-2 CELL RECOGNIITON USING SUPPORT VECTOR MACHINE UNDER CLASS SKEW
title_full_unstemmed MITOTIC HEP-2 CELL RECOGNIITON USING SUPPORT VECTOR MACHINE UNDER CLASS SKEW
title_sort mitotic hep-2 cell recogniiton using support vector machine under class skew
publisher Universiti Teknologi Petronas
publishDate 2014
url http://utpedia.utp.edu.my/13450/1/22.pdf
http://utpedia.utp.edu.my/13450/
_version_ 1739831898542178304
score 13.211869

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