The association of adiponectin and leptin with objectively measured physical activity among adults: a brief review
Strong evidence shows that physical inactivity increases the risk of many adverse health conditions, including major non-communicable diseases such as coronary heart disease, type 2 diabetes, and various cancers as well as shortens life expectancy. There are many mechanisms that may act through t...
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| Main Authors: | , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2015
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| Subjects: | |
| Online Access: | http://eprints.unisza.edu.my/691/1/FH03-FSK-15-04471.pdf http://eprints.unisza.edu.my/691/ |
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| Summary: | Strong evidence shows that physical inactivity increases the risk of many adverse health
conditions, including major non-communicable diseases such as coronary heart disease,
type 2 diabetes, and various cancers as well as shortens life expectancy. There are many
mechanisms that may act through the effects of physical activity on health outcomes which
resulting changes in circulating adiponectin and leptin. However studies on the association
between self-reported physical activity level and adipokines found inconclusive results.
Therefore this study aims to compile and analyse existing scientific evidence regarding
the association between adiponectin and leptin with objectively measured physical activity
among adults. Medline, PubMed, and Scopus databases were searched using specific
keywords for articles related to the association between objectively measured physical
activity on adiponectin and leptin. Only cross sectional studies among adults between year
2000 to 2015 were included. Studies that used subjective assessment of physical activity
were excluded. A total of 1274 papers were retried from initial search. Only six studies
met the inclusion criteria (n= 961). Five studies showed the effects of objectively measured
physical activity on adiponectin and four studies on leptin. All four studies involving leptin
showed a weak to moderate inverse association (r=0.213-0.443) and for adiponectin, three
out of five studies showed a weak to moderate positive association (r=0.31-0.438) with
objectively measured physical activity. Lower serum leptin and higher serum adiponectin
concentration were associated with increased level of physical activity. As a conclusion,
there is consistent evidence on the association between objectively measured physical
activity and adipokines especially on leptin. More well-designed cross sectional studies
using a larger sample size are needed to confirm these findings. |
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