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Dietary carbohydrate, fiber and sugar and risk of breast cancer according to menopausal status in Malaysia

Background: Dietary carbohydrate, fiber and sugar intake has been shown to play a role in the etiology of breast cancer, but the findings have been inconsistent and limited to developed countries with higher cancer incidence. Objective: To examine the association of premenopausal and postmenopausal...

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Main Authors: Sharifah Wajihah Wafa, Syed Saadun Tarek Wafa, Suhaina, Sulaiman, Soraya Hanie, Shaharudin
Format: Article
Language:English
English
Published: 2014
Subjects:
R Medicine (General)
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spelling my-unisza-ir.54852022-09-13T04:43:56Z http://eprints.unisza.edu.my/5485/ Dietary carbohydrate, fiber and sugar and risk of breast cancer according to menopausal status in Malaysia Sharifah Wajihah Wafa, Syed Saadun Tarek Wafa Suhaina, Sulaiman Soraya Hanie, Shaharudin R Medicine (General) Background: Dietary carbohydrate, fiber and sugar intake has been shown to play a role in the etiology of breast cancer, but the findings have been inconsistent and limited to developed countries with higher cancer incidence. Objective: To examine the association of premenopausal and postmenopausal breast cancer risk with dietary carbohydrate, fiber and sugar intake. Materials and methods: This population based case-control study was conducted in Malaysia with 382 breast cancer patients and 382 controls. Food intake pattern was assessed via an interviewer-administered food frequency questionnaire. Logistic regression was used to compute odds ratios (OR) with 95% confidence intervals (CI) and a broad range of potential confounders were included in analysis. Results: A significant two fold increased risk of breast cancer among premenopausal (OR Q4 to Q1=1.93, 95%CI: 1.53-2.61, p-trend=0.001) and postmenopausal (OR Q4 to Q1=1.87, 95%CI: 1.03-2.61, p-trend=0.045) women was observed in the highest quartile of sugar. A higher intake of dietary fiber was associated with a significantly lower breast cancer risk among both premenopausal (OR Q4 to Q1=0.31, 95%CI: 0.12-0.79, p-trend=0.009) and postmenopausal (OR Q4 to Q1=0.23, 95%CI: 0.07-0.76, p-trend=0.031) women. Conclusions: Sugar and dietary fiber intake were independently related to pre- and postmenopausal breast cancer risk. However, no association was observed for dietary carbohydrate intake. 2014 Article PeerReviewed image en http://eprints.unisza.edu.my/5485/1/FH02-FPSK-14-01326.jpg image en http://eprints.unisza.edu.my/5485/2/FH02-FPSK-15-02372.jpg Sharifah Wajihah Wafa, Syed Saadun Tarek Wafa and Suhaina, Sulaiman and Soraya Hanie, Shaharudin (2014) Dietary carbohydrate, fiber and sugar and risk of breast cancer according to menopausal status in Malaysia. Asian Pacific Journal of Cancer Prevention, 15 (14). pp. 5959-5964. ISSN 15137368
institution Universiti Sultan Zainal Abidin
building UNISZA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sultan Zainal Abidin
content_source UNISZA Institutional Repository
url_provider https://eprints.unisza.edu.my/
language English
English
topic R Medicine (General)
spellingShingle R Medicine (General)
Sharifah Wajihah Wafa, Syed Saadun Tarek Wafa
Suhaina, Sulaiman
Soraya Hanie, Shaharudin
Dietary carbohydrate, fiber and sugar and risk of breast cancer according to menopausal status in Malaysia
description Background: Dietary carbohydrate, fiber and sugar intake has been shown to play a role in the etiology of breast cancer, but the findings have been inconsistent and limited to developed countries with higher cancer incidence. Objective: To examine the association of premenopausal and postmenopausal breast cancer risk with dietary carbohydrate, fiber and sugar intake. Materials and methods: This population based case-control study was conducted in Malaysia with 382 breast cancer patients and 382 controls. Food intake pattern was assessed via an interviewer-administered food frequency questionnaire. Logistic regression was used to compute odds ratios (OR) with 95% confidence intervals (CI) and a broad range of potential confounders were included in analysis. Results: A significant two fold increased risk of breast cancer among premenopausal (OR Q4 to Q1=1.93, 95%CI: 1.53-2.61, p-trend=0.001) and postmenopausal (OR Q4 to Q1=1.87, 95%CI: 1.03-2.61, p-trend=0.045) women was observed in the highest quartile of sugar. A higher intake of dietary fiber was associated with a significantly lower breast cancer risk among both premenopausal (OR Q4 to Q1=0.31, 95%CI: 0.12-0.79, p-trend=0.009) and postmenopausal (OR Q4 to Q1=0.23, 95%CI: 0.07-0.76, p-trend=0.031) women. Conclusions: Sugar and dietary fiber intake were independently related to pre- and postmenopausal breast cancer risk. However, no association was observed for dietary carbohydrate intake.
format Article
author Sharifah Wajihah Wafa, Syed Saadun Tarek Wafa
Suhaina, Sulaiman
Soraya Hanie, Shaharudin
author_facet Sharifah Wajihah Wafa, Syed Saadun Tarek Wafa
Suhaina, Sulaiman
Soraya Hanie, Shaharudin
author_sort Sharifah Wajihah Wafa, Syed Saadun Tarek Wafa
title Dietary carbohydrate, fiber and sugar and risk of breast cancer according to menopausal status in Malaysia
title_short Dietary carbohydrate, fiber and sugar and risk of breast cancer according to menopausal status in Malaysia
title_full Dietary carbohydrate, fiber and sugar and risk of breast cancer according to menopausal status in Malaysia
title_fullStr Dietary carbohydrate, fiber and sugar and risk of breast cancer according to menopausal status in Malaysia
title_full_unstemmed Dietary carbohydrate, fiber and sugar and risk of breast cancer according to menopausal status in Malaysia
title_sort dietary carbohydrate, fiber and sugar and risk of breast cancer according to menopausal status in malaysia
publishDate 2014
url http://eprints.unisza.edu.my/5485/1/FH02-FPSK-14-01326.jpg
http://eprints.unisza.edu.my/5485/2/FH02-FPSK-15-02372.jpg
http://eprints.unisza.edu.my/5485/
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score 13.211869

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