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Minimal modeling of glucose-insulin interactions: In the intravenous glucose tolerance test

The minimal model of glucose and insulin plasma levels is commonly used to analyze the results of glucose tolerance tests in humans. In this paper, a mathematical model for describing the glucose infusion rate was introduced. The minimal model was used to study a few sets of published data includ...

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主要な著者: Mustafa, Mamat, Kamariah Noor, Ab Kahar
フォーマット: 論文
言語:English
出版事項: 2014
主題:
QD Chemistry
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spelling my-unisza-ir.50902022-09-13T05:15:25Z http://eprints.unisza.edu.my/5090/ Minimal modeling of glucose-insulin interactions: In the intravenous glucose tolerance test Mustafa, Mamat Kamariah Noor, Ab Kahar QD Chemistry The minimal model of glucose and insulin plasma levels is commonly used to analyze the results of glucose tolerance tests in humans. In this paper, a mathematical model for describing the glucose infusion rate was introduced. The minimal model was used to study a few sets of published data including healthy humans and type 2 diabetes. The glucose-insulin system as a dynamic integrated physiological system and generated the real optimized model parameters from the experimental data using the modified minimal model. The averaged R2 value between measured and calculated plasma concentrations wais 0.977, which indicates excellent agreement. 2014 Article PeerReviewed image en http://eprints.unisza.edu.my/5090/1/FH02-FIK-14-00738.jpg Mustafa, Mamat and Kamariah Noor, Ab Kahar (2014) Minimal modeling of glucose-insulin interactions: In the intravenous glucose tolerance test. Applied Mathematical Sciences, 8 (66). pp. 3273-3281. ISSN 13147552 [P]
institution Universiti Sultan Zainal Abidin
building UNISZA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sultan Zainal Abidin
content_source UNISZA Institutional Repository
url_provider https://eprints.unisza.edu.my/
language English
topic QD Chemistry
spellingShingle QD Chemistry
Mustafa, Mamat
Kamariah Noor, Ab Kahar
Minimal modeling of glucose-insulin interactions: In the intravenous glucose tolerance test
description The minimal model of glucose and insulin plasma levels is commonly used to analyze the results of glucose tolerance tests in humans. In this paper, a mathematical model for describing the glucose infusion rate was introduced. The minimal model was used to study a few sets of published data including healthy humans and type 2 diabetes. The glucose-insulin system as a dynamic integrated physiological system and generated the real optimized model parameters from the experimental data using the modified minimal model. The averaged R2 value between measured and calculated plasma concentrations wais 0.977, which indicates excellent agreement.
format Article
author Mustafa, Mamat
Kamariah Noor, Ab Kahar
author_facet Mustafa, Mamat
Kamariah Noor, Ab Kahar
author_sort Mustafa, Mamat
title Minimal modeling of glucose-insulin interactions: In the intravenous glucose tolerance test
title_short Minimal modeling of glucose-insulin interactions: In the intravenous glucose tolerance test
title_full Minimal modeling of glucose-insulin interactions: In the intravenous glucose tolerance test
title_fullStr Minimal modeling of glucose-insulin interactions: In the intravenous glucose tolerance test
title_full_unstemmed Minimal modeling of glucose-insulin interactions: In the intravenous glucose tolerance test
title_sort minimal modeling of glucose-insulin interactions: in the intravenous glucose tolerance test
publishDate 2014
url http://eprints.unisza.edu.my/5090/1/FH02-FIK-14-00738.jpg
http://eprints.unisza.edu.my/5090/
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score 13.251813

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