Cover Image

Peroxisome Proliferactor Activated Receptor Gamma (PPAR-γ) Polymorphism Towards Obesity Endemic in Malaysia

Obesity is pandemic and its associated co-morbidities, nowdays pose a major threat to global health systems. Obesity is often associated with adipose tissue dysfunction in which adiposity hypertrophy, adipose tissue hypo-perfusion and hypoxia, adipose tissue inflammation and macrophage infiltratio...

Full description

Saved in:
Bibliographic Details
Main Authors: Atif, Amin Baig, Mohd Khairi, Zahri @ Johari, U.s., Mahadeva Rao
Format: Article
Language:English
Published: 2013
Subjects:
Q Science (General)
Online Access:http://eprints.unisza.edu.my/4390/1/FH02-FPSK-14-00709.pdf
http://eprints.unisza.edu.my/4390/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-unisza-ir.4390
record_format eprints
spelling my-unisza-ir.43902022-09-13T05:24:48Z http://eprints.unisza.edu.my/4390/ Peroxisome Proliferactor Activated Receptor Gamma (PPAR-γ) Polymorphism Towards Obesity Endemic in Malaysia Atif, Amin Baig Mohd Khairi, Zahri @ Johari U.s., Mahadeva Rao Q Science (General) Obesity is pandemic and its associated co-morbidities, nowdays pose a major threat to global health systems. Obesity is often associated with adipose tissue dysfunction in which adiposity hypertrophy, adipose tissue hypo-perfusion and hypoxia, adipose tissue inflammation and macrophage infiltration are interrelated with each other in the pathophysiology and pathogenesis of obesity. Here we will discuss how genetic studies, through the discovery of peroxisome proliferactor-activated receptor gamma (PPAR-γ) have contributed to our understanding of the central pathways which govern the mechanism of how obesity develops in human. In Malaysia, we are still lacking information about the interaction of PPAR-γ polymorphism with obesity. We anticipate that future studies should emphasize more on genetic research, especially on lipid studies so that we could develop a most efficient and achievable targeted approach to the prevention and control of obesity accordingly. 2013-07 Article PeerReviewed text en http://eprints.unisza.edu.my/4390/1/FH02-FPSK-14-00709.pdf Atif, Amin Baig and Mohd Khairi, Zahri @ Johari and U.s., Mahadeva Rao (2013) Peroxisome Proliferactor Activated Receptor Gamma (PPAR-γ) Polymorphism Towards Obesity Endemic in Malaysia. Vedic Research International Cell Signaling, 1 (1). pp. 7-10. ISSN 2330-0302
institution Universiti Sultan Zainal Abidin
building UNISZA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sultan Zainal Abidin
content_source UNISZA Institutional Repository
url_provider https://eprints.unisza.edu.my/
language English
topic Q Science (General)
spellingShingle Q Science (General)
Atif, Amin Baig
Mohd Khairi, Zahri @ Johari
U.s., Mahadeva Rao
Peroxisome Proliferactor Activated Receptor Gamma (PPAR-γ) Polymorphism Towards Obesity Endemic in Malaysia
description Obesity is pandemic and its associated co-morbidities, nowdays pose a major threat to global health systems. Obesity is often associated with adipose tissue dysfunction in which adiposity hypertrophy, adipose tissue hypo-perfusion and hypoxia, adipose tissue inflammation and macrophage infiltration are interrelated with each other in the pathophysiology and pathogenesis of obesity. Here we will discuss how genetic studies, through the discovery of peroxisome proliferactor-activated receptor gamma (PPAR-γ) have contributed to our understanding of the central pathways which govern the mechanism of how obesity develops in human. In Malaysia, we are still lacking information about the interaction of PPAR-γ polymorphism with obesity. We anticipate that future studies should emphasize more on genetic research, especially on lipid studies so that we could develop a most efficient and achievable targeted approach to the prevention and control of obesity accordingly.
format Article
author Atif, Amin Baig
Mohd Khairi, Zahri @ Johari
U.s., Mahadeva Rao
author_facet Atif, Amin Baig
Mohd Khairi, Zahri @ Johari
U.s., Mahadeva Rao
author_sort Atif, Amin Baig
title Peroxisome Proliferactor Activated Receptor Gamma (PPAR-γ) Polymorphism Towards Obesity Endemic in Malaysia
title_short Peroxisome Proliferactor Activated Receptor Gamma (PPAR-γ) Polymorphism Towards Obesity Endemic in Malaysia
title_full Peroxisome Proliferactor Activated Receptor Gamma (PPAR-γ) Polymorphism Towards Obesity Endemic in Malaysia
title_fullStr Peroxisome Proliferactor Activated Receptor Gamma (PPAR-γ) Polymorphism Towards Obesity Endemic in Malaysia
title_full_unstemmed Peroxisome Proliferactor Activated Receptor Gamma (PPAR-γ) Polymorphism Towards Obesity Endemic in Malaysia
title_sort peroxisome proliferactor activated receptor gamma (ppar-γ) polymorphism towards obesity endemic in malaysia
publishDate 2013
url http://eprints.unisza.edu.my/4390/1/FH02-FPSK-14-00709.pdf
http://eprints.unisza.edu.my/4390/
_version_ 1744358509135265792
score 13.211869

Similar Items