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The effect of xylene on histology of spleen in female adolescent sprague dawley rat

Introduction: Xylene is an aromatic hydrocarbon that is widely used in industries such as rubber and printing. The spleen tissue contains red pulp and white pulp and lymphocytes that serve as body defense mechanism for foreign and invasion of toxic substances. We hypothesize that xylene exposure mig...

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Main Authors: Mohd Aidi, A.M., Hasmah, A., Nurul Aiman, M.Y., Yasrul Izad, A.B.
Format: Conference or Workshop Item
Language:English
Published: 2018
Subjects:
Q Science (General)
QH301 Biology
Online Access:http://eprints.unisza.edu.my/1290/1/FH03-FP-19-23766.pdf
http://eprints.unisza.edu.my/1290/
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spelling my-unisza-ir.12902020-11-11T07:40:38Z http://eprints.unisza.edu.my/1290/ The effect of xylene on histology of spleen in female adolescent sprague dawley rat Mohd Aidi, A.M. Hasmah, A. Nurul Aiman, M.Y. Yasrul Izad, A.B. Q Science (General) QH301 Biology Introduction: Xylene is an aromatic hydrocarbon that is widely used in industries such as rubber and printing. The spleen tissue contains red pulp and white pulp and lymphocytes that serve as body defense mechanism for foreign and invasion of toxic substances. We hypothesize that xylene exposure might affect cellular morphology of spleen in the white pulp. Quantitative analysis on the size of the white pulp of spleen after the exposure to xylene was done. Method: Twelve Sprague Dawley female rats (n=12) were randomly divided into two groups; control group and xylene group. Rats were sacrificed and spleen were removed for to histological studies. Cross sections of spleen were stained by haematoxylin and eosins to analyze the changes of white pulp on the spleen. The white pulp marginal zone and germinal center were compared within groups. Results: Image captured showed that xylene exhibits cause an increase in the size of white pulp of spleen indicates an increase in the number of lymphocytes. There were significant difference between the control group and the xylene exposure group. The median size of the white pulp of spleen in the control group was 80361.42µm and xylene group is 113047.78µm. Conclusion: In conclusion, xylene increases the size of the white pulp of spleen in female Sprague-Dawley rat thus increases the number of lymphocytes. 2018 Conference or Workshop Item NonPeerReviewed text en http://eprints.unisza.edu.my/1290/1/FH03-FP-19-23766.pdf Mohd Aidi, A.M. and Hasmah, A. and Nurul Aiman, M.Y. and Yasrul Izad, A.B. (2018) The effect of xylene on histology of spleen in female adolescent sprague dawley rat. In: POSTGRADUATE RESEARCH DAY, PPSK, USM, 25 Nov 2018, KUBANG KERIAN, KELANTAN.
institution Universiti Sultan Zainal Abidin
building UNISZA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sultan Zainal Abidin
content_source UNISZA Institutional Repository
url_provider https://eprints.unisza.edu.my/
language English
topic Q Science (General)
QH301 Biology
spellingShingle Q Science (General)
QH301 Biology
Mohd Aidi, A.M.
Hasmah, A.
Nurul Aiman, M.Y.
Yasrul Izad, A.B.
The effect of xylene on histology of spleen in female adolescent sprague dawley rat
description Introduction: Xylene is an aromatic hydrocarbon that is widely used in industries such as rubber and printing. The spleen tissue contains red pulp and white pulp and lymphocytes that serve as body defense mechanism for foreign and invasion of toxic substances. We hypothesize that xylene exposure might affect cellular morphology of spleen in the white pulp. Quantitative analysis on the size of the white pulp of spleen after the exposure to xylene was done. Method: Twelve Sprague Dawley female rats (n=12) were randomly divided into two groups; control group and xylene group. Rats were sacrificed and spleen were removed for to histological studies. Cross sections of spleen were stained by haematoxylin and eosins to analyze the changes of white pulp on the spleen. The white pulp marginal zone and germinal center were compared within groups. Results: Image captured showed that xylene exhibits cause an increase in the size of white pulp of spleen indicates an increase in the number of lymphocytes. There were significant difference between the control group and the xylene exposure group. The median size of the white pulp of spleen in the control group was 80361.42µm and xylene group is 113047.78µm. Conclusion: In conclusion, xylene increases the size of the white pulp of spleen in female Sprague-Dawley rat thus increases the number of lymphocytes.
format Conference or Workshop Item
author Mohd Aidi, A.M.
Hasmah, A.
Nurul Aiman, M.Y.
Yasrul Izad, A.B.
author_facet Mohd Aidi, A.M.
Hasmah, A.
Nurul Aiman, M.Y.
Yasrul Izad, A.B.
author_sort Mohd Aidi, A.M.
title The effect of xylene on histology of spleen in female adolescent sprague dawley rat
title_short The effect of xylene on histology of spleen in female adolescent sprague dawley rat
title_full The effect of xylene on histology of spleen in female adolescent sprague dawley rat
title_fullStr The effect of xylene on histology of spleen in female adolescent sprague dawley rat
title_full_unstemmed The effect of xylene on histology of spleen in female adolescent sprague dawley rat
title_sort effect of xylene on histology of spleen in female adolescent sprague dawley rat
publishDate 2018
url http://eprints.unisza.edu.my/1290/1/FH03-FP-19-23766.pdf
http://eprints.unisza.edu.my/1290/
_version_ 1683235000528404480
score 13.211869

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