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Genotypic and allelic frequencies of HF1 (rs11549465) variation in association with antropometric indices and lipid profile in Malay obese attributes

Globesity will be affecting more than one billion people by 2030 nod is associated with diseases like diabetes mellitus, metabolic syndrome and cardiovascular disease. Hypoxia-inducible factor 1 (HIFI) is a protein and trascriptional factor, which is a major regulator of oxygen homeostasis. Our obj...

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Main Authors: Atif, Amin Baig, Ahmad Zubaidi, A.latif, Nordin, Simbak
Format: Conference or Workshop Item
Language:English
English
Published: 2018
Subjects:
GE Environmental Sciences
QH301 Biology
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spelling my-unisza-ir.12222020-11-10T07:12:15Z http://eprints.unisza.edu.my/1222/ Genotypic and allelic frequencies of HF1 (rs11549465) variation in association with antropometric indices and lipid profile in Malay obese attributes Atif, Amin Baig Ahmad Zubaidi, A.latif Nordin, Simbak GE Environmental Sciences QH301 Biology Globesity will be affecting more than one billion people by 2030 nod is associated with diseases like diabetes mellitus, metabolic syndrome and cardiovascular disease. Hypoxia-inducible factor 1 (HIFI) is a protein and trascriptional factor, which is a major regulator of oxygen homeostasis. Our objective was to determine the genotypic and allelic frequency of HIF1 (rsl 11549465) variation in correlation with anthropometric indices and lipid profile in Malay obese attributes using RFLP-PCR and statistical analysis. This was a case control study with a total of 180 subjects (90 obese and 90 non-obese) recruited form record of Malaysian obesity DNA bank. We found according to means of genotypic and allelic frequencies of HIF1 (rs 11549465) variation in the sample group, there is lack of TT genotype in both obese and control groups, and there was no difference between both groups according to allelic frequencies, which in obese were (C 100% vs T 15.6% ) and in controls (C 100% vs T 17.8%), while C is the wild type and T is the mutated allele. 2018 Conference or Workshop Item NonPeerReviewed image en http://eprints.unisza.edu.my/1222/1/FH03-FP-19-24375.jpg image en http://eprints.unisza.edu.my/1222/2/FH03-FP-19-24376.jpg Atif, Amin Baig and Ahmad Zubaidi, A.latif and Nordin, Simbak (2018) Genotypic and allelic frequencies of HF1 (rs11549465) variation in association with antropometric indices and lipid profile in Malay obese attributes. In: 3rd International Symposium on Advances in Molecular Biology of Plants and Health Sciences, 19 Dec 2018, Lahore, Pakistan.
institution Universiti Sultan Zainal Abidin
building UNISZA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sultan Zainal Abidin
content_source UNISZA Institutional Repository
url_provider https://eprints.unisza.edu.my/
language English
English
topic GE Environmental Sciences
QH301 Biology
spellingShingle GE Environmental Sciences
QH301 Biology
Atif, Amin Baig
Ahmad Zubaidi, A.latif
Nordin, Simbak
Genotypic and allelic frequencies of HF1 (rs11549465) variation in association with antropometric indices and lipid profile in Malay obese attributes
description Globesity will be affecting more than one billion people by 2030 nod is associated with diseases like diabetes mellitus, metabolic syndrome and cardiovascular disease. Hypoxia-inducible factor 1 (HIFI) is a protein and trascriptional factor, which is a major regulator of oxygen homeostasis. Our objective was to determine the genotypic and allelic frequency of HIF1 (rsl 11549465) variation in correlation with anthropometric indices and lipid profile in Malay obese attributes using RFLP-PCR and statistical analysis. This was a case control study with a total of 180 subjects (90 obese and 90 non-obese) recruited form record of Malaysian obesity DNA bank. We found according to means of genotypic and allelic frequencies of HIF1 (rs 11549465) variation in the sample group, there is lack of TT genotype in both obese and control groups, and there was no difference between both groups according to allelic frequencies, which in obese were (C 100% vs T 15.6% ) and in controls (C 100% vs T 17.8%), while C is the wild type and T is the mutated allele.
format Conference or Workshop Item
author Atif, Amin Baig
Ahmad Zubaidi, A.latif
Nordin, Simbak
author_facet Atif, Amin Baig
Ahmad Zubaidi, A.latif
Nordin, Simbak
author_sort Atif, Amin Baig
title Genotypic and allelic frequencies of HF1 (rs11549465) variation in association with antropometric indices and lipid profile in Malay obese attributes
title_short Genotypic and allelic frequencies of HF1 (rs11549465) variation in association with antropometric indices and lipid profile in Malay obese attributes
title_full Genotypic and allelic frequencies of HF1 (rs11549465) variation in association with antropometric indices and lipid profile in Malay obese attributes
title_fullStr Genotypic and allelic frequencies of HF1 (rs11549465) variation in association with antropometric indices and lipid profile in Malay obese attributes
title_full_unstemmed Genotypic and allelic frequencies of HF1 (rs11549465) variation in association with antropometric indices and lipid profile in Malay obese attributes
title_sort genotypic and allelic frequencies of hf1 (rs11549465) variation in association with antropometric indices and lipid profile in malay obese attributes
publishDate 2018
url http://eprints.unisza.edu.my/1222/1/FH03-FP-19-24375.jpg
http://eprints.unisza.edu.my/1222/2/FH03-FP-19-24376.jpg
http://eprints.unisza.edu.my/1222/
_version_ 1683234990534426624
score 13.211869

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