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The hidden salmon patch: ocular lymphoma mistaken as Vogt Koyanagi disease

Ocular inflammation from various causes may have similar clinical presentation thus careful clinical evaluations are mandatory particularly when the disease appear to be resistant to treatment. This paper reports a case of ocular lymphoma which was initially treated as Vogt Koyanagi Harada disease a...

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Main Authors: Nazima SA,, Muhaya M,, Kok, HS, Hazlita Mohd Isa,
Format: Article
Language:English
Published: Faculty of Medicine, UKM Medical Centre 2016
Online Access:http://journalarticle.ukm.my/9836/1/10._Nazima_et_al..pdf
http://journalarticle.ukm.my/9836/
http://jsurgacad.com/toc/6/1
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spelling my-ukm.journal.98362016-12-14T06:50:59Z http://journalarticle.ukm.my/9836/ The hidden salmon patch: ocular lymphoma mistaken as Vogt Koyanagi disease Nazima SA, Muhaya M, Kok, HS Hazlita Mohd Isa, Ocular inflammation from various causes may have similar clinical presentation thus careful clinical evaluations are mandatory particularly when the disease appear to be resistant to treatment. This paper reports a case of ocular lymphoma which was initially treated as Vogt Koyanagi Harada disease at a different centre. A 65-year-old Sudanese man complained of gradual worsening left eye vision. Careful ocular and slit lamp examination revealed a conjunctival lesion with choroidal infiltration as well as exudative retinal detachment. Computed tomography scan (CT scan) showed left eye axial proptosis, and a homogenous enhancing mass at the posterior coat of the globe. Tissue biopsy of the conjunctival lesion revealed marginal Zone B cell (MALT type), low grade, non-Hodgkin’s lymphoma. AS the ocular signs and symptoms progressed, chemotherapy was initiated. The proptosis, exudative retinal detachment, disc hyperemia and swelling improved after chemotherapy. The post treatment CT scan showed reduction of the posterior ocular coat mass. The possibility of malignant lymphoma should be considered in patients with resistant uveitis despite administration of corticosteroid. Ocular lymphoma is an indolent tumour with good prognosis. Careful ocular examination, adequate imaging studies followed by early surgical biopsy will contribute to early diagnosis. Faculty of Medicine, UKM Medical Centre 2016 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9836/1/10._Nazima_et_al..pdf Nazima SA, and Muhaya M, and Kok, HS and Hazlita Mohd Isa, (2016) The hidden salmon patch: ocular lymphoma mistaken as Vogt Koyanagi disease. Journal of Surgical Academia, 6 (1). pp. 46-50. ISSN 2231-7481 http://jsurgacad.com/toc/6/1
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Ocular inflammation from various causes may have similar clinical presentation thus careful clinical evaluations are mandatory particularly when the disease appear to be resistant to treatment. This paper reports a case of ocular lymphoma which was initially treated as Vogt Koyanagi Harada disease at a different centre. A 65-year-old Sudanese man complained of gradual worsening left eye vision. Careful ocular and slit lamp examination revealed a conjunctival lesion with choroidal infiltration as well as exudative retinal detachment. Computed tomography scan (CT scan) showed left eye axial proptosis, and a homogenous enhancing mass at the posterior coat of the globe. Tissue biopsy of the conjunctival lesion revealed marginal Zone B cell (MALT type), low grade, non-Hodgkin’s lymphoma. AS the ocular signs and symptoms progressed, chemotherapy was initiated. The proptosis, exudative retinal detachment, disc hyperemia and swelling improved after chemotherapy. The post treatment CT scan showed reduction of the posterior ocular coat mass. The possibility of malignant lymphoma should be considered in patients with resistant uveitis despite administration of corticosteroid. Ocular lymphoma is an indolent tumour with good prognosis. Careful ocular examination, adequate imaging studies followed by early surgical biopsy will contribute to early diagnosis.
format Article
author Nazima SA,
Muhaya M,
Kok, HS
Hazlita Mohd Isa,
spellingShingle Nazima SA,
Muhaya M,
Kok, HS
Hazlita Mohd Isa,
The hidden salmon patch: ocular lymphoma mistaken as Vogt Koyanagi disease
author_facet Nazima SA,
Muhaya M,
Kok, HS
Hazlita Mohd Isa,
author_sort Nazima SA,
title The hidden salmon patch: ocular lymphoma mistaken as Vogt Koyanagi disease
title_short The hidden salmon patch: ocular lymphoma mistaken as Vogt Koyanagi disease
title_full The hidden salmon patch: ocular lymphoma mistaken as Vogt Koyanagi disease
title_fullStr The hidden salmon patch: ocular lymphoma mistaken as Vogt Koyanagi disease
title_full_unstemmed The hidden salmon patch: ocular lymphoma mistaken as Vogt Koyanagi disease
title_sort hidden salmon patch: ocular lymphoma mistaken as vogt koyanagi disease
publisher Faculty of Medicine, UKM Medical Centre
publishDate 2016
url http://journalarticle.ukm.my/9836/1/10._Nazima_et_al..pdf
http://journalarticle.ukm.my/9836/
http://jsurgacad.com/toc/6/1
_version_ 1643737920630161408
score 13.211869

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