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The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management

Low Grade Papillary Nasopharyngeal Adenocarcinoma (LGPAC) is a very rare tumour of mucosal origin compared to a higher incidence of well differentiated keratinized/non-keratinized nasopharyngeal carcinoma. It is an epithelial tumour with glandular differentiation. Its papillary figure seen histologi...

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Main Authors: Noor Dina H,, Gendeh BH,
Format: Article
Language:English
Published: Penerbit UKM 2015
Online Access:http://journalarticle.ukm.my/9280/1/7.%2520Noor%2520Dina%2520H%2520et%2520al..pdf
http://journalarticle.ukm.my/9280/
http://www.medicineandhealthukm.com
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spelling my-ukm.journal.92802016-12-14T06:49:27Z http://journalarticle.ukm.my/9280/ The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management Noor Dina H, Gendeh BH, Low Grade Papillary Nasopharyngeal Adenocarcinoma (LGPAC) is a very rare tumour of mucosal origin compared to a higher incidence of well differentiated keratinized/non-keratinized nasopharyngeal carcinoma. It is an epithelial tumour with glandular differentiation. Its papillary figure seen histologically, is also seen in metastatic papillary thyroid carcinoma. This has caused a significant challenge to the Pathologist to differentiate primary papillary nasopharyngeal adenocarcinoma and metastatic tumour. Thyroid Transcription Factor-1 (TTF-1) is also expressed in subsets of papillary nasopharyngeal adenocarcinoma, which is valuable as a diagnostic tool. LGPAC is a benign-like malignant neoplasm. An early diagnosis with a complete tumour removal via conventional excision or endoscopic approach has offered a good prognosis with low risk of recurrence. Penerbit UKM 2015-12-01 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/9280/1/7.%2520Noor%2520Dina%2520H%2520et%2520al..pdf Noor Dina H, and Gendeh BH, (2015) The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management. Medicine & Health, 10 (2). pp. 137-140. ISSN 1823-2140 http://www.medicineandhealthukm.com
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Low Grade Papillary Nasopharyngeal Adenocarcinoma (LGPAC) is a very rare tumour of mucosal origin compared to a higher incidence of well differentiated keratinized/non-keratinized nasopharyngeal carcinoma. It is an epithelial tumour with glandular differentiation. Its papillary figure seen histologically, is also seen in metastatic papillary thyroid carcinoma. This has caused a significant challenge to the Pathologist to differentiate primary papillary nasopharyngeal adenocarcinoma and metastatic tumour. Thyroid Transcription Factor-1 (TTF-1) is also expressed in subsets of papillary nasopharyngeal adenocarcinoma, which is valuable as a diagnostic tool. LGPAC is a benign-like malignant neoplasm. An early diagnosis with a complete tumour removal via conventional excision or endoscopic approach has offered a good prognosis with low risk of recurrence.
format Article
author Noor Dina H,
Gendeh BH,
spellingShingle Noor Dina H,
Gendeh BH,
The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management
author_facet Noor Dina H,
Gendeh BH,
author_sort Noor Dina H,
title The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management
title_short The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management
title_full The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management
title_fullStr The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management
title_full_unstemmed The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management
title_sort rare primary low grade papillary adenocarcinoma of nasopharynx: a diagnostic challenge and management
publisher Penerbit UKM
publishDate 2015
url http://journalarticle.ukm.my/9280/1/7.%2520Noor%2520Dina%2520H%2520et%2520al..pdf
http://journalarticle.ukm.my/9280/
http://www.medicineandhealthukm.com
_version_ 1643737739141578752
score 13.211869

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