Cover Image

The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men

Bone turnover markers (BTMs) are useful in the assessment of bone health status. However, the infl uence of age, ethnicity and body anthropometry on the level of BTMs in men remains understudied. This study aimed to determine the influence of these factors on the level of BTM, namely osteoclacin (OC...

Full description

Saved in:
Bibliographic Details
Main Authors: Ima Nirwana Soelaiman,, Kok, Yong Chin, Isa Naina Mohamed,, Wan Zurinah Wan Ngah,
Format: Article
Language:English
Published: penerbit ukm 2014
Subjects:
RA Public aspects of medicine
Online Access:http://journalarticle.ukm.my/7478/1/The_Influence_of_Age%2C_Ethnicity_and_Body_Anthropometry.pdf
http://journalarticle.ukm.my/7478/
http://ejournal.ukm.my/jskm/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-ukm.journal.7478
record_format eprints
spelling my-ukm.journal.74782016-12-14T06:44:13Z http://journalarticle.ukm.my/7478/ The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men Ima Nirwana Soelaiman, Kok, Yong Chin Isa Naina Mohamed, Wan Zurinah Wan Ngah, RA Public aspects of medicine Bone turnover markers (BTMs) are useful in the assessment of bone health status. However, the infl uence of age, ethnicity and body anthropometry on the level of BTMs in men remains understudied. This study aimed to determine the influence of these factors on the level of BTM, namely osteoclacin (OC) and C-terminal telopeptides of type 1 collagen (CTX-1) among Malay and Chinese men (N = 407) aged 20 years and above in Klang Valley. The subjects were recruited using purposive sampling method. Their height, body weight and body mass index were measured. Their blood was collected in the morning for serum OC and CTX-1 analysis using enzyme-linked immunoasorbent assays. Results showed that OC and CTX-1 levels were significantly higher in Malay compared to Chinese men (p < 0.05). Highest levels of OC and CTX-1 were observed in men aged 20-29 years, while the lowest levels were found among men aged 30-39 years (p < 0.005). No significant diff erences in the levels of both markers were found between the older men and those aged 30-39 years (p > 0.005). There were significant and negative correlations between OC and body mass index and weight, which were significant for men aged 20-39 years only (p < 0.05). Body anthropometry was not correlated with CTX-1 level in men (p > 0.05). As a conclusion, levels of BTMs in Malaysian men could be infl uenced by age, ethnicity and body anthropometry. Thus, these factors should be taken into consideration in the evaluation of bone health status of men using BTMs. penerbit ukm 2014 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/7478/1/The_Influence_of_Age%2C_Ethnicity_and_Body_Anthropometry.pdf Ima Nirwana Soelaiman, and Kok, Yong Chin and Isa Naina Mohamed, and Wan Zurinah Wan Ngah, (2014) The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men. Jurnal Sains Kesihatan Malaysia, 12 (1). pp. 7-13. ISSN 1675-8161 http://ejournal.ukm.my/jskm/
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
topic RA Public aspects of medicine
spellingShingle RA Public aspects of medicine
Ima Nirwana Soelaiman,
Kok, Yong Chin
Isa Naina Mohamed,
Wan Zurinah Wan Ngah,
The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
description Bone turnover markers (BTMs) are useful in the assessment of bone health status. However, the infl uence of age, ethnicity and body anthropometry on the level of BTMs in men remains understudied. This study aimed to determine the influence of these factors on the level of BTM, namely osteoclacin (OC) and C-terminal telopeptides of type 1 collagen (CTX-1) among Malay and Chinese men (N = 407) aged 20 years and above in Klang Valley. The subjects were recruited using purposive sampling method. Their height, body weight and body mass index were measured. Their blood was collected in the morning for serum OC and CTX-1 analysis using enzyme-linked immunoasorbent assays. Results showed that OC and CTX-1 levels were significantly higher in Malay compared to Chinese men (p < 0.05). Highest levels of OC and CTX-1 were observed in men aged 20-29 years, while the lowest levels were found among men aged 30-39 years (p < 0.005). No significant diff erences in the levels of both markers were found between the older men and those aged 30-39 years (p > 0.005). There were significant and negative correlations between OC and body mass index and weight, which were significant for men aged 20-39 years only (p < 0.05). Body anthropometry was not correlated with CTX-1 level in men (p > 0.05). As a conclusion, levels of BTMs in Malaysian men could be infl uenced by age, ethnicity and body anthropometry. Thus, these factors should be taken into consideration in the evaluation of bone health status of men using BTMs.
format Article
author Ima Nirwana Soelaiman,
Kok, Yong Chin
Isa Naina Mohamed,
Wan Zurinah Wan Ngah,
author_facet Ima Nirwana Soelaiman,
Kok, Yong Chin
Isa Naina Mohamed,
Wan Zurinah Wan Ngah,
author_sort Ima Nirwana Soelaiman,
title The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
title_short The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
title_full The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
title_fullStr The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
title_full_unstemmed The influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type I collagen in men
title_sort influence of age, ethnicity and body anthropometry on the level of serum osteocalcin and terminal-c telopeptides of type i collagen in men
publisher penerbit ukm
publishDate 2014
url http://journalarticle.ukm.my/7478/1/The_Influence_of_Age%2C_Ethnicity_and_Body_Anthropometry.pdf
http://journalarticle.ukm.my/7478/
http://ejournal.ukm.my/jskm/
_version_ 1643737142514417664
score 13.211869

Similar Items