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Vitrectomy for breakthrough bleeding in age related macular degeneration and polypoidal choroidal vasculopathy in a Malaysian hospital

This study aimed to review the risk factors and clinical outcomes of patients undergoing pars planar vitrectomy (PPV) for breakthrough bleeding (BTB) from age related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). We performed a retrospective review of medical records of 346...

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Main Authors: Bastion, MLC, Amelah, MAQ, Wong, HS
Format: Article
Language:English
Published: Department of Surgery, UKM Medical Centre 2012
Online Access:http://journalarticle.ukm.my/5938/1/05-MS1067_%2821-26%29.pdf
http://journalarticle.ukm.my/5938/
http://jsurgacad.com/
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spelling my-ukm.journal.59382016-12-14T06:39:54Z http://journalarticle.ukm.my/5938/ Vitrectomy for breakthrough bleeding in age related macular degeneration and polypoidal choroidal vasculopathy in a Malaysian hospital Bastion, MLC Amelah, MAQ Wong, HS This study aimed to review the risk factors and clinical outcomes of patients undergoing pars planar vitrectomy (PPV) for breakthrough bleeding (BTB) from age related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). We performed a retrospective review of medical records of 346 patients operated by the vitreoretinal unit at Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Kuala Lumpur, Malaysia from January 2008 - June 2011. We found eight eyes of 8 patients with AMD/IPCV-related BTB who underwent PPV. Mean age of patients was 64.4 years (range 41-80 years) with 5 males. Five were Chinese. Duration of symptoms ranged from days to months. Four patients were on anti-coagulants. Two had history of prior photodynamic therapy. There were five cases of PCV, of which three were macular in location. All three cases of AMD were macular. Intraoperative intravitreal ranibizumab injection was given in three cases and two had combined vitrectomy and cataract extraction. All cases reported improvement in visual acuity with four cases achieving 6/60 or better post operatively including two cases of extramacular PCV achieving 6/9 vision. Mean follow-up was 60 weeks. Postoperative complications included retinal tear and detachment in one case, reattached on reoperation. Six patients had a history of hypertension including one individual with stroke. Our small series indicates a predominance of Chinese individuals with BTB. Usage of anticoagulants and hypertension may be a predisposing factor. Better visual prognosis occurs with extramacular lesions which tend to be of PCV type. Department of Surgery, UKM Medical Centre 2012 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/5938/1/05-MS1067_%2821-26%29.pdf Bastion, MLC and Amelah, MAQ and Wong, HS (2012) Vitrectomy for breakthrough bleeding in age related macular degeneration and polypoidal choroidal vasculopathy in a Malaysian hospital. Journal of Surgical Academia, 2 (2). pp. 21-26. ISSN 2231-7481 http://jsurgacad.com/
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description This study aimed to review the risk factors and clinical outcomes of patients undergoing pars planar vitrectomy (PPV) for breakthrough bleeding (BTB) from age related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). We performed a retrospective review of medical records of 346 patients operated by the vitreoretinal unit at Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Kuala Lumpur, Malaysia from January 2008 - June 2011. We found eight eyes of 8 patients with AMD/IPCV-related BTB who underwent PPV. Mean age of patients was 64.4 years (range 41-80 years) with 5 males. Five were Chinese. Duration of symptoms ranged from days to months. Four patients were on anti-coagulants. Two had history of prior photodynamic therapy. There were five cases of PCV, of which three were macular in location. All three cases of AMD were macular. Intraoperative intravitreal ranibizumab injection was given in three cases and two had combined vitrectomy and cataract extraction. All cases reported improvement in visual acuity with four cases achieving 6/60 or better post operatively including two cases of extramacular PCV achieving 6/9 vision. Mean follow-up was 60 weeks. Postoperative complications included retinal tear and detachment in one case, reattached on reoperation. Six patients had a history of hypertension including one individual with stroke. Our small series indicates a predominance of Chinese individuals with BTB. Usage of anticoagulants and hypertension may be a predisposing factor. Better visual prognosis occurs with extramacular lesions which tend to be of PCV type.
format Article
author Bastion, MLC
Amelah, MAQ
Wong, HS
spellingShingle Bastion, MLC
Amelah, MAQ
Wong, HS
Vitrectomy for breakthrough bleeding in age related macular degeneration and polypoidal choroidal vasculopathy in a Malaysian hospital
author_facet Bastion, MLC
Amelah, MAQ
Wong, HS
author_sort Bastion, MLC
title Vitrectomy for breakthrough bleeding in age related macular degeneration and polypoidal choroidal vasculopathy in a Malaysian hospital
title_short Vitrectomy for breakthrough bleeding in age related macular degeneration and polypoidal choroidal vasculopathy in a Malaysian hospital
title_full Vitrectomy for breakthrough bleeding in age related macular degeneration and polypoidal choroidal vasculopathy in a Malaysian hospital
title_fullStr Vitrectomy for breakthrough bleeding in age related macular degeneration and polypoidal choroidal vasculopathy in a Malaysian hospital
title_full_unstemmed Vitrectomy for breakthrough bleeding in age related macular degeneration and polypoidal choroidal vasculopathy in a Malaysian hospital
title_sort vitrectomy for breakthrough bleeding in age related macular degeneration and polypoidal choroidal vasculopathy in a malaysian hospital
publisher Department of Surgery, UKM Medical Centre
publishDate 2012
url http://journalarticle.ukm.my/5938/1/05-MS1067_%2821-26%29.pdf
http://journalarticle.ukm.my/5938/
http://jsurgacad.com/
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score 13.211869

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