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Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study

The objective of this study was to establish the association of plasma fibronectin in saliva of pregnant women with history of miscarriage(s). A total of 25 pregnant women with history of miscarriage(s) were recruited at the Antenatal Clinic of University Malaya Medical Centre (UMMC), Kuala Lumpur a...

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Main Authors: Farha Ariffin,, Salmah Kamin,, Jamiyah Hassan,, Haliza Hasan,
Format: Article
Language:English
Published: Universiti Kebangsaan Malaysia 2013
Online Access:http://journalarticle.ukm.my/5701/1/06%2520Farha.pdf
http://journalarticle.ukm.my/5701/
http://www.ukm.my/jsm/
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spelling my-ukm.journal.57012016-12-14T06:39:14Z http://journalarticle.ukm.my/5701/ Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study Farha Ariffin, Salmah Kamin, Jamiyah Hassan, Haliza Hasan, The objective of this study was to establish the association of plasma fibronectin in saliva of pregnant women with history of miscarriage(s). A total of 25 pregnant women with history of miscarriage(s) were recruited at the Antenatal Clinic of University Malaya Medical Centre (UMMC), Kuala Lumpur as the test group and 16 pregnant women without any history of miscarriage served as control. All the subjects fulfilled a set of inclusion and exclusion criteria. Periodontal examination was performed to determine subjects’ periodontal status. Saliva samples were collected and enzyme-linked immunosorbent assay (ELISA) was used to detect the plasma fibronectin in these samples. Mann-Whitney test was used to determine the significance of differences seen. The study showed a statistically significant higher median plasma fibronectin level in the saliva samples of the test group with a median level of 0.10 μg/mL compared with the control group with a mean value of 0.00 μg/mL (p-value =0.023). However, there was no significant difference in the level of plasma fibronectin in the saliva samples of pregnant women with chronic periodontitis compared with the group with healthy gingiva (p-value= 0.118). As a conclusion, there was a positive association between plasma fibronectin in saliva of women and history of miscarriages compared with the control group in this case study. Universiti Kebangsaan Malaysia 2013-01 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/5701/1/06%2520Farha.pdf Farha Ariffin, and Salmah Kamin, and Jamiyah Hassan, and Haliza Hasan, (2013) Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study. Sains Malaysiana, 42 (1). pp. 33-38. ISSN 0126-6039 http://www.ukm.my/jsm/
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description The objective of this study was to establish the association of plasma fibronectin in saliva of pregnant women with history of miscarriage(s). A total of 25 pregnant women with history of miscarriage(s) were recruited at the Antenatal Clinic of University Malaya Medical Centre (UMMC), Kuala Lumpur as the test group and 16 pregnant women without any history of miscarriage served as control. All the subjects fulfilled a set of inclusion and exclusion criteria. Periodontal examination was performed to determine subjects’ periodontal status. Saliva samples were collected and enzyme-linked immunosorbent assay (ELISA) was used to detect the plasma fibronectin in these samples. Mann-Whitney test was used to determine the significance of differences seen. The study showed a statistically significant higher median plasma fibronectin level in the saliva samples of the test group with a median level of 0.10 μg/mL compared with the control group with a mean value of 0.00 μg/mL (p-value =0.023). However, there was no significant difference in the level of plasma fibronectin in the saliva samples of pregnant women with chronic periodontitis compared with the group with healthy gingiva (p-value= 0.118). As a conclusion, there was a positive association between plasma fibronectin in saliva of women and history of miscarriages compared with the control group in this case study.
format Article
author Farha Ariffin,
Salmah Kamin,
Jamiyah Hassan,
Haliza Hasan,
spellingShingle Farha Ariffin,
Salmah Kamin,
Jamiyah Hassan,
Haliza Hasan,
Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
author_facet Farha Ariffin,
Salmah Kamin,
Jamiyah Hassan,
Haliza Hasan,
author_sort Farha Ariffin,
title Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
title_short Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
title_full Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
title_fullStr Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
title_full_unstemmed Plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
title_sort plasma fibronectin in saliva of women with history of miscarriage(s) and periodontal disease - a pilot study
publisher Universiti Kebangsaan Malaysia
publishDate 2013
url http://journalarticle.ukm.my/5701/1/06%2520Farha.pdf
http://journalarticle.ukm.my/5701/
http://www.ukm.my/jsm/
_version_ 1643736507209482240
score 13.211869

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