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Cost-effectiveness analysis of continuous venovenous hemofiltration therapy in the treatment of sepsis in Hospital Universiti Kebangsaan Malaysia: a comparison between high volume and standard dose hemofiltration

Background: A randomised clinical trial was carried out to study the cost-effectiveness of continuous venovenous hemofiltration using high volume and standard volume. Methods: Study was done through interviews involving patients or their relatives and document review on patients’ treatment and progr...

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Main Authors: A M Rizal,, M H Enna,, S M Aljunid,, A G Rohana,, Z Soehardy,, C T K Norella,
Format: Article
Language:English
Published: Department Of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia 2006
Online Access:http://journalarticle.ukm.my/4460/1/Vol12%281%29-Rizal.pdf
http://journalarticle.ukm.my/4460/
http://www.communityhealthjournal.org/detailarticle.asp?id=125&issue=Vol12(1):2006
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spelling my-ukm.journal.44602016-12-14T06:36:05Z http://journalarticle.ukm.my/4460/ Cost-effectiveness analysis of continuous venovenous hemofiltration therapy in the treatment of sepsis in Hospital Universiti Kebangsaan Malaysia: a comparison between high volume and standard dose hemofiltration A M Rizal, M H Enna, S M Aljunid, A G Rohana, Z Soehardy, C T K Norella, Background: A randomised clinical trial was carried out to study the cost-effectiveness of continuous venovenous hemofiltration using high volume and standard volume. Methods: Study was done through interviews involving patients or their relatives and document review on patients’ treatment and progress note during the hemofiltration therapy in the Intensive Care Unit, Hospital University Kebangsaan Malaysia. Study also involved secondary data analysis and a structured questionnaire survey to assess the treatment and medical cost incurred by the hospital during the continuous venovenous hemofiltration therapy. Results: The result of this study showed that the continuous venovenous hemofiltration given at high volume 4-6 litres/hour is more cost effective than standard volume of 2 litres/hour. The Sequential Organ Failure Assessment (SOFA) score reduction in the high volume hemofiltration is 3.0 units over 24 hours. This reduction is higher than the standard volume hemofiltration which is only 0.5 unit over 24 hours. Conclusions: High volume hemofiltration is more cost effective than standard volume therapy, where only RM 5,552 compared to RM 23,512 is needed for every one unit of SOFA score reduction respectively. Department Of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia 2006 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/4460/1/Vol12%281%29-Rizal.pdf A M Rizal, and M H Enna, and S M Aljunid, and A G Rohana, and Z Soehardy, and C T K Norella, (2006) Cost-effectiveness analysis of continuous venovenous hemofiltration therapy in the treatment of sepsis in Hospital Universiti Kebangsaan Malaysia: a comparison between high volume and standard dose hemofiltration. Jurnal Kesihatan Masyarakat, 12 (1). pp. 1-8. ISSN 1675-1663 http://www.communityhealthjournal.org/detailarticle.asp?id=125&issue=Vol12(1):2006
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Background: A randomised clinical trial was carried out to study the cost-effectiveness of continuous venovenous hemofiltration using high volume and standard volume. Methods: Study was done through interviews involving patients or their relatives and document review on patients’ treatment and progress note during the hemofiltration therapy in the Intensive Care Unit, Hospital University Kebangsaan Malaysia. Study also involved secondary data analysis and a structured questionnaire survey to assess the treatment and medical cost incurred by the hospital during the continuous venovenous hemofiltration therapy. Results: The result of this study showed that the continuous venovenous hemofiltration given at high volume 4-6 litres/hour is more cost effective than standard volume of 2 litres/hour. The Sequential Organ Failure Assessment (SOFA) score reduction in the high volume hemofiltration is 3.0 units over 24 hours. This reduction is higher than the standard volume hemofiltration which is only 0.5 unit over 24 hours. Conclusions: High volume hemofiltration is more cost effective than standard volume therapy, where only RM 5,552 compared to RM 23,512 is needed for every one unit of SOFA score reduction respectively.
format Article
author A M Rizal,
M H Enna,
S M Aljunid,
A G Rohana,
Z Soehardy,
C T K Norella,
spellingShingle A M Rizal,
M H Enna,
S M Aljunid,
A G Rohana,
Z Soehardy,
C T K Norella,
Cost-effectiveness analysis of continuous venovenous hemofiltration therapy in the treatment of sepsis in Hospital Universiti Kebangsaan Malaysia: a comparison between high volume and standard dose hemofiltration
author_facet A M Rizal,
M H Enna,
S M Aljunid,
A G Rohana,
Z Soehardy,
C T K Norella,
author_sort A M Rizal,
title Cost-effectiveness analysis of continuous venovenous hemofiltration therapy in the treatment of sepsis in Hospital Universiti Kebangsaan Malaysia: a comparison between high volume and standard dose hemofiltration
title_short Cost-effectiveness analysis of continuous venovenous hemofiltration therapy in the treatment of sepsis in Hospital Universiti Kebangsaan Malaysia: a comparison between high volume and standard dose hemofiltration
title_full Cost-effectiveness analysis of continuous venovenous hemofiltration therapy in the treatment of sepsis in Hospital Universiti Kebangsaan Malaysia: a comparison between high volume and standard dose hemofiltration
title_fullStr Cost-effectiveness analysis of continuous venovenous hemofiltration therapy in the treatment of sepsis in Hospital Universiti Kebangsaan Malaysia: a comparison between high volume and standard dose hemofiltration
title_full_unstemmed Cost-effectiveness analysis of continuous venovenous hemofiltration therapy in the treatment of sepsis in Hospital Universiti Kebangsaan Malaysia: a comparison between high volume and standard dose hemofiltration
title_sort cost-effectiveness analysis of continuous venovenous hemofiltration therapy in the treatment of sepsis in hospital universiti kebangsaan malaysia: a comparison between high volume and standard dose hemofiltration
publisher Department Of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia
publishDate 2006
url http://journalarticle.ukm.my/4460/1/Vol12%281%29-Rizal.pdf
http://journalarticle.ukm.my/4460/
http://www.communityhealthjournal.org/detailarticle.asp?id=125&issue=Vol12(1):2006
_version_ 1643736086303735808
score 13.211869

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