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Uterine sex cord tumour- Management dilemma

Uterine sex cord tumour is a very rare tumour with uncertain management strategies and prognosis. A 61-year-old, nulliparous, who was not on hormone replacement therapy, presented with first episode of postmenopausal bleeding. A transvaginal scan revealed an enlarged uterus with thick endometrial li...

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Main Authors: Mohamad Nasir S,, Lim PS,, Swaminathan M,, Hatta MD,, Mohd Hashim O,
Format: Article
Language:English
Published: Department of Surgery, UKM Medical Centre 2011
Online Access:http://journalarticle.ukm.my/2956/1/7-9.pdf
http://journalarticle.ukm.my/2956/
http://jsurgacad.com/
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spelling my-ukm.journal.29562016-12-14T06:33:10Z http://journalarticle.ukm.my/2956/ Uterine sex cord tumour- Management dilemma Mohamad Nasir S, Lim PS, Swaminathan M, Hatta MD, Mohd Hashim O, Uterine sex cord tumour is a very rare tumour with uncertain management strategies and prognosis. A 61-year-old, nulliparous, who was not on hormone replacement therapy, presented with first episode of postmenopausal bleeding. A transvaginal scan revealed an enlarged uterus with thick endometrial lining and features of multiple degenerated fibroid. Endometrial biopsy was negative for malignancy. Computed tomography of the abdomen and pelvis confirmed the mass, with atrophic ovaries and incidental finding of bilateral hydronephrosis requiring stentings. Otherwise, there were no pelvic lymph nodes enlargement. Our impression was a uterine sarcoma and we decided for total abdominal hysterectomy with bilateral salpingooophorectomy. Surprisingly, the histology report confirmed uterine sex cord tumour. There are less cases of recurrence and there is no general consensus on the management. However, we decided for adjuvant chemotherapy (BEP regime) as the malignant cells infiltrated more than half of myometrial thickness, with good outcome. Department of Surgery, UKM Medical Centre 2011-10 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/2956/1/7-9.pdf Mohamad Nasir S, and Lim PS, and Swaminathan M, and Hatta MD, and Mohd Hashim O, (2011) Uterine sex cord tumour- Management dilemma. Journal of Surgical Academia, 1 (2). pp. 7-9. ISSN 2231-7481 http://jsurgacad.com/
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Uterine sex cord tumour is a very rare tumour with uncertain management strategies and prognosis. A 61-year-old, nulliparous, who was not on hormone replacement therapy, presented with first episode of postmenopausal bleeding. A transvaginal scan revealed an enlarged uterus with thick endometrial lining and features of multiple degenerated fibroid. Endometrial biopsy was negative for malignancy. Computed tomography of the abdomen and pelvis confirmed the mass, with atrophic ovaries and incidental finding of bilateral hydronephrosis requiring stentings. Otherwise, there were no pelvic lymph nodes enlargement. Our impression was a uterine sarcoma and we decided for total abdominal hysterectomy with bilateral salpingooophorectomy. Surprisingly, the histology report confirmed uterine sex cord tumour. There are less cases of recurrence and there is no general consensus on the management. However, we decided for adjuvant chemotherapy (BEP regime) as the malignant cells infiltrated more than half of myometrial thickness, with good outcome.
format Article
author Mohamad Nasir S,
Lim PS,
Swaminathan M,
Hatta MD,
Mohd Hashim O,
spellingShingle Mohamad Nasir S,
Lim PS,
Swaminathan M,
Hatta MD,
Mohd Hashim O,
Uterine sex cord tumour- Management dilemma
author_facet Mohamad Nasir S,
Lim PS,
Swaminathan M,
Hatta MD,
Mohd Hashim O,
author_sort Mohamad Nasir S,
title Uterine sex cord tumour- Management dilemma
title_short Uterine sex cord tumour- Management dilemma
title_full Uterine sex cord tumour- Management dilemma
title_fullStr Uterine sex cord tumour- Management dilemma
title_full_unstemmed Uterine sex cord tumour- Management dilemma
title_sort uterine sex cord tumour- management dilemma
publisher Department of Surgery, UKM Medical Centre
publishDate 2011
url http://journalarticle.ukm.my/2956/1/7-9.pdf
http://journalarticle.ukm.my/2956/
http://jsurgacad.com/
_version_ 1643735552801898496
score 13.211869

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