A systematic review of the clinical effectiveness of aloe vera for the prevention and treatment of chronic wounds

Aloe vera is an herbaceous and perennial plant that belongs to the Liliaceae family and used for many medicinal purposes. Aloe vera have been associated with the treatment of skin burns and postoperative wound healing but not many clinical studies have been conducted to evaluate its effectiveness ag...

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Main Authors: Ahmad Nur Afieq Idrus,, Rehman, Khurram, Mohd Hanif Zulfakar,
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2023
Online Access:http://journalarticle.ukm.my/22800/1/SEN%2014.pdf
http://journalarticle.ukm.my/22800/
https://www.ukm.my/jsm/english_journals/vol52num6_2023/contentsVol52num6_2023.html
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spelling my-ukm.journal.228002024-01-03T05:33:40Z http://journalarticle.ukm.my/22800/ A systematic review of the clinical effectiveness of aloe vera for the prevention and treatment of chronic wounds Ahmad Nur Afieq Idrus, Rehman, Khurram Mohd Hanif Zulfakar, Aloe vera is an herbaceous and perennial plant that belongs to the Liliaceae family and used for many medicinal purposes. Aloe vera have been associated with the treatment of skin burns and postoperative wound healing but not many clinical studies have been conducted to evaluate its effectiveness against chronic wounds such as pressure injury. The present study aimed to systematically review clinical trials investigating the effect of Aloe vera on the prevention and healing of chronic wounds. To identify all related published studies, Science Direct, Google Scholar, PubMed, and Ovid MEDLINE databases were searched in English language from the year 2015-2022. All clinical trials using Aloe vera gel, cream, or derivatives that included a control group with placebo or comparison with other treatments were included in the study according to the PRISMA selection process. In total, 11 trials that met the inclusion criteria were reviewed. The results of the studies showed successful use of Aloe vera in the prevention and treatment of chronic wounds including pressure injuries, chronic wound ulcers, diabetic foot ulcers, chronic anal fissures, and traumatic oral ulceration due to orthodontic appliances. Based on its safety and efficacy profile, this review concluded that Aloe vera has potential benefits to be used as a complementary or alternative treatment in chronic wounds along with conventional methods. Its ability to retain skin moisture and preservation of skin integrity supports its use in the prevention of ulcers. Penerbit Universiti Kebangsaan Malaysia 2023 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/22800/1/SEN%2014.pdf Ahmad Nur Afieq Idrus, and Rehman, Khurram and Mohd Hanif Zulfakar, (2023) A systematic review of the clinical effectiveness of aloe vera for the prevention and treatment of chronic wounds. Sains Malaysiana, 52 (6). pp. 1785-1794. ISSN 0126-6039 https://www.ukm.my/jsm/english_journals/vol52num6_2023/contentsVol52num6_2023.html
institution Universiti Kebangsaan Malaysia
building Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Aloe vera is an herbaceous and perennial plant that belongs to the Liliaceae family and used for many medicinal purposes. Aloe vera have been associated with the treatment of skin burns and postoperative wound healing but not many clinical studies have been conducted to evaluate its effectiveness against chronic wounds such as pressure injury. The present study aimed to systematically review clinical trials investigating the effect of Aloe vera on the prevention and healing of chronic wounds. To identify all related published studies, Science Direct, Google Scholar, PubMed, and Ovid MEDLINE databases were searched in English language from the year 2015-2022. All clinical trials using Aloe vera gel, cream, or derivatives that included a control group with placebo or comparison with other treatments were included in the study according to the PRISMA selection process. In total, 11 trials that met the inclusion criteria were reviewed. The results of the studies showed successful use of Aloe vera in the prevention and treatment of chronic wounds including pressure injuries, chronic wound ulcers, diabetic foot ulcers, chronic anal fissures, and traumatic oral ulceration due to orthodontic appliances. Based on its safety and efficacy profile, this review concluded that Aloe vera has potential benefits to be used as a complementary or alternative treatment in chronic wounds along with conventional methods. Its ability to retain skin moisture and preservation of skin integrity supports its use in the prevention of ulcers.
format Article
author Ahmad Nur Afieq Idrus,
Rehman, Khurram
Mohd Hanif Zulfakar,
spellingShingle Ahmad Nur Afieq Idrus,
Rehman, Khurram
Mohd Hanif Zulfakar,
A systematic review of the clinical effectiveness of aloe vera for the prevention and treatment of chronic wounds
author_facet Ahmad Nur Afieq Idrus,
Rehman, Khurram
Mohd Hanif Zulfakar,
author_sort Ahmad Nur Afieq Idrus,
title A systematic review of the clinical effectiveness of aloe vera for the prevention and treatment of chronic wounds
title_short A systematic review of the clinical effectiveness of aloe vera for the prevention and treatment of chronic wounds
title_full A systematic review of the clinical effectiveness of aloe vera for the prevention and treatment of chronic wounds
title_fullStr A systematic review of the clinical effectiveness of aloe vera for the prevention and treatment of chronic wounds
title_full_unstemmed A systematic review of the clinical effectiveness of aloe vera for the prevention and treatment of chronic wounds
title_sort systematic review of the clinical effectiveness of aloe vera for the prevention and treatment of chronic wounds
publisher Penerbit Universiti Kebangsaan Malaysia
publishDate 2023
url http://journalarticle.ukm.my/22800/1/SEN%2014.pdf
http://journalarticle.ukm.my/22800/
https://www.ukm.my/jsm/english_journals/vol52num6_2023/contentsVol52num6_2023.html
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score 13.211869