Cover Image

The acquisition, analyses and interpretation of fMRI data: a study on functional specialisation in primary auditory cortices

In this study, functional magnetic resonance imaging (fMRI) is used to investigate func-tional specialisation in human auditory cortices during listening. A silent fMRI paradigm was used to reduce the scanner sound artefacts on functional images. The subject was instructed to pay attention to the wh...

Full description

Saved in:
Bibliographic Details
Main Authors: Yusoff AN,, Abdul Hamid K,, Mohamad M,, Abd Hamid AI,
Format: Article
Language:English
Published: Penerbit UKM 2008
Online Access:http://journalarticle.ukm.my/2059/1/12-300-317_%28MS_064%29.pdf
http://journalarticle.ukm.my/2059/
http://www.ppukm.ukm.my/ukmmcjournal/index.php
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-ukm.journal.2059
record_format eprints
spelling my-ukm.journal.20592016-12-14T06:30:47Z http://journalarticle.ukm.my/2059/ The acquisition, analyses and interpretation of fMRI data: a study on functional specialisation in primary auditory cortices Yusoff AN, Abdul Hamid K, Mohamad M, Abd Hamid AI, In this study, functional magnetic resonance imaging (fMRI) is used to investigate func-tional specialisation in human auditory cortices during listening. A silent fMRI paradigm was used to reduce the scanner sound artefacts on functional images. The subject was instructed to pay attention to the white noise stimulus binaurally given at an inten-sity level of 70 dB higher than the hearing level for normal people. Functional speciali-sation was studied using the Matlab-based Statistical Parametric Mapping (SPM5) software by means of fixed effects (FFX), random effects (RFX) and conjunction analyses. Individual analyses on all subjects indicated asymmetrical bilateral activation of the left and right hemispheres in Brodmann areas (BA) 22, 41 and 42, involving the primary and secondary auditory cortices. The percentage of signal change is larger in the BA22, 41 and 42 on the right as compared to the ones on the left (p>0.05). The average number of activated voxels in all the respective Brodmann areas are higher in the right hemisphere than in the left (p>0.05). FFX results showed that the point of maximum intensity was in the right BA41 whereby 599±1 activated voxels were ob-served in the right temporal lobe as compared to 485±1 in the left temporal lobe. The RFX results were consistent with that of FFX. The analysis of conjunction which fol-lowed, showed that the right BA41 and left BA22 as the common activated areas in all subjects. The results confirmed the specialisation of the right auditory cortices in pro-cessing non verbal stimuli Penerbit UKM 2008 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/2059/1/12-300-317_%28MS_064%29.pdf Yusoff AN, and Abdul Hamid K, and Mohamad M, and Abd Hamid AI, (2008) The acquisition, analyses and interpretation of fMRI data: a study on functional specialisation in primary auditory cortices. Medicine & Health, 3 (2). pp. 300-317. ISSN 1823-2140 http://www.ppukm.ukm.my/ukmmcjournal/index.php
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description In this study, functional magnetic resonance imaging (fMRI) is used to investigate func-tional specialisation in human auditory cortices during listening. A silent fMRI paradigm was used to reduce the scanner sound artefacts on functional images. The subject was instructed to pay attention to the white noise stimulus binaurally given at an inten-sity level of 70 dB higher than the hearing level for normal people. Functional speciali-sation was studied using the Matlab-based Statistical Parametric Mapping (SPM5) software by means of fixed effects (FFX), random effects (RFX) and conjunction analyses. Individual analyses on all subjects indicated asymmetrical bilateral activation of the left and right hemispheres in Brodmann areas (BA) 22, 41 and 42, involving the primary and secondary auditory cortices. The percentage of signal change is larger in the BA22, 41 and 42 on the right as compared to the ones on the left (p>0.05). The average number of activated voxels in all the respective Brodmann areas are higher in the right hemisphere than in the left (p>0.05). FFX results showed that the point of maximum intensity was in the right BA41 whereby 599±1 activated voxels were ob-served in the right temporal lobe as compared to 485±1 in the left temporal lobe. The RFX results were consistent with that of FFX. The analysis of conjunction which fol-lowed, showed that the right BA41 and left BA22 as the common activated areas in all subjects. The results confirmed the specialisation of the right auditory cortices in pro-cessing non verbal stimuli
format Article
author Yusoff AN,
Abdul Hamid K,
Mohamad M,
Abd Hamid AI,
spellingShingle Yusoff AN,
Abdul Hamid K,
Mohamad M,
Abd Hamid AI,
The acquisition, analyses and interpretation of fMRI data: a study on functional specialisation in primary auditory cortices
author_facet Yusoff AN,
Abdul Hamid K,
Mohamad M,
Abd Hamid AI,
author_sort Yusoff AN,
title The acquisition, analyses and interpretation of fMRI data: a study on functional specialisation in primary auditory cortices
title_short The acquisition, analyses and interpretation of fMRI data: a study on functional specialisation in primary auditory cortices
title_full The acquisition, analyses and interpretation of fMRI data: a study on functional specialisation in primary auditory cortices
title_fullStr The acquisition, analyses and interpretation of fMRI data: a study on functional specialisation in primary auditory cortices
title_full_unstemmed The acquisition, analyses and interpretation of fMRI data: a study on functional specialisation in primary auditory cortices
title_sort acquisition, analyses and interpretation of fmri data: a study on functional specialisation in primary auditory cortices
publisher Penerbit UKM
publishDate 2008
url http://journalarticle.ukm.my/2059/1/12-300-317_%28MS_064%29.pdf
http://journalarticle.ukm.my/2059/
http://www.ppukm.ukm.my/ukmmcjournal/index.php
_version_ 1643735253282455552
score 13.211869

Similar Items