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Preventive effects of Moringa oleifera on obesity and hyperlipidaemia : a systematic review

Obesity and hyperlipidaemia are metabolic dysregulations, arising from poor lifestyle and excessive dietary intakes which may contribute to many chronic diseases if not treated. Studies have shown that plant-based supplementations can suppress this metabolic dysregulation. Moringa oleifera (MO) is a...

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Main Authors: Sivanesan Raja Kumar,, Norliza Muhammad,, Mary Nancy Fernandez,, Nur Azlina Mohd Fahami,
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2022
Online Access:http://journalarticle.ukm.my/20245/1/18.pdf
http://journalarticle.ukm.my/20245/
https://www.ukm.my/jsm/malay_journals/jilid51bil7_2022/KandunganJilid51Bil7_2022.html
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spelling my-ukm.journal.202452022-10-25T07:47:43Z http://journalarticle.ukm.my/20245/ Preventive effects of Moringa oleifera on obesity and hyperlipidaemia : a systematic review Sivanesan Raja Kumar, Norliza Muhammad, Mary Nancy Fernandez, Nur Azlina Mohd Fahami, Obesity and hyperlipidaemia are metabolic dysregulations, arising from poor lifestyle and excessive dietary intakes which may contribute to many chronic diseases if not treated. Studies have shown that plant-based supplementations can suppress this metabolic dysregulation. Moringa oleifera (MO) is a plant that is known to be nutritious and can alleviate obesity and hyperlipidaemia owing to its medicinal properties. A literature search on the effects of MO on obesity and hyperlipidaemia using electronic databases which included Ovid Medline and Scopus was performed. Specific descriptors were used to perform the search strategy. The articles were selected based on the principles that report on the effects of MO on obesity and hyperlipidaemia. Titles of the articles were screened for Moringa oleifera OR obesity OR hyperlipidaemia. Twenty-nine articles, 19 from Ovid Medline and 10 from Scopus were selected based on the inclusion and exclusion criteria. A flow chart was created to represent the study selection. Based on the chosen articles, MO was shown to suppress obesity and hyperlipidaemia directly and indirectly through the regulation of gene expression, enzyme activity and adipocytokines. Through animal trials, MO demonstrated promising results in alleviating obesity and hyperlipidaemia. More human trials should be performed to strengthen the accomplished effects seen on animals. As there were no side effects identified in animal studies, it could be recommended to patients with obesity and hyperlipidaemia. Penerbit Universiti Kebangsaan Malaysia 2022-07 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/20245/1/18.pdf Sivanesan Raja Kumar, and Norliza Muhammad, and Mary Nancy Fernandez, and Nur Azlina Mohd Fahami, (2022) Preventive effects of Moringa oleifera on obesity and hyperlipidaemia : a systematic review. Sains Malaysiana, 51 (7). pp. 2159-2171. ISSN 0126-6039 https://www.ukm.my/jsm/malay_journals/jilid51bil7_2022/KandunganJilid51Bil7_2022.html
institution Universiti Kebangsaan Malaysia
building Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Obesity and hyperlipidaemia are metabolic dysregulations, arising from poor lifestyle and excessive dietary intakes which may contribute to many chronic diseases if not treated. Studies have shown that plant-based supplementations can suppress this metabolic dysregulation. Moringa oleifera (MO) is a plant that is known to be nutritious and can alleviate obesity and hyperlipidaemia owing to its medicinal properties. A literature search on the effects of MO on obesity and hyperlipidaemia using electronic databases which included Ovid Medline and Scopus was performed. Specific descriptors were used to perform the search strategy. The articles were selected based on the principles that report on the effects of MO on obesity and hyperlipidaemia. Titles of the articles were screened for Moringa oleifera OR obesity OR hyperlipidaemia. Twenty-nine articles, 19 from Ovid Medline and 10 from Scopus were selected based on the inclusion and exclusion criteria. A flow chart was created to represent the study selection. Based on the chosen articles, MO was shown to suppress obesity and hyperlipidaemia directly and indirectly through the regulation of gene expression, enzyme activity and adipocytokines. Through animal trials, MO demonstrated promising results in alleviating obesity and hyperlipidaemia. More human trials should be performed to strengthen the accomplished effects seen on animals. As there were no side effects identified in animal studies, it could be recommended to patients with obesity and hyperlipidaemia.
format Article
author Sivanesan Raja Kumar,
Norliza Muhammad,
Mary Nancy Fernandez,
Nur Azlina Mohd Fahami,
spellingShingle Sivanesan Raja Kumar,
Norliza Muhammad,
Mary Nancy Fernandez,
Nur Azlina Mohd Fahami,
Preventive effects of Moringa oleifera on obesity and hyperlipidaemia : a systematic review
author_facet Sivanesan Raja Kumar,
Norliza Muhammad,
Mary Nancy Fernandez,
Nur Azlina Mohd Fahami,
author_sort Sivanesan Raja Kumar,
title Preventive effects of Moringa oleifera on obesity and hyperlipidaemia : a systematic review
title_short Preventive effects of Moringa oleifera on obesity and hyperlipidaemia : a systematic review
title_full Preventive effects of Moringa oleifera on obesity and hyperlipidaemia : a systematic review
title_fullStr Preventive effects of Moringa oleifera on obesity and hyperlipidaemia : a systematic review
title_full_unstemmed Preventive effects of Moringa oleifera on obesity and hyperlipidaemia : a systematic review
title_sort preventive effects of moringa oleifera on obesity and hyperlipidaemia : a systematic review
publisher Penerbit Universiti Kebangsaan Malaysia
publishDate 2022
url http://journalarticle.ukm.my/20245/1/18.pdf
http://journalarticle.ukm.my/20245/
https://www.ukm.my/jsm/malay_journals/jilid51bil7_2022/KandunganJilid51Bil7_2022.html
_version_ 1748181786897154048
score 13.211869

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