Detection of BCR/ABL gene in chronic Myeloid Leukaemia: comparison of Fluorescence in situ Hybridisation (FISH), conventional Cytogenetics and Polymerase Chain Reaction (PCR) techniques
The reciprocal translocation t(9;22)(q34;q11) which gives rise to the Philadelphia (Ph1) chromosome and BCR/ABL fusion gene, plays a pivotal role in the diagnosis and pathogenesis of chronic myeloid leukemia (CML). In this study, we evaluated the role of fluorescence in situ hybridisation (FISH) in...
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Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Penerbit UKM
2006
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Online Access: | http://journalarticle.ukm.my/1829/1/02._5-13_%28MH_006%29.pdf http://journalarticle.ukm.my/1829/ http://www.ppukm.ukm.my/ukmmcjournal/index.php |
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