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Alkaloid caulerpin and cytotoxic activity against NCL-H460 lung cancer cells isolated along with β-sitosterol from the Halimeda cylindracea decaisne

Alkaloid caulerpin (1), along with β-sitosterol (2), were isolated from the n-hexane extract of the macroalga Halimeda cylindracea Decaisne. The chemical structure was identified by a spectroscopic method including IR, MS, UV, NMR 1D, NMR 2D, and comparison with data of spectra previously reported....

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Main Authors: Dini, Iwan, Soekamto, Nunuk Hariani, Firdaus,, Supratman, Unang, Jalifah Latip,
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2021
Online Access:http://journalarticle.ukm.my/18063/1/14.pdf
http://journalarticle.ukm.my/18063/
https://www.ukm.my/jsm/malay_journals/jilid50bil9_2021/KandunganJilid50Bil9_2021.html
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spelling my-ukm.journal.180632022-02-18T00:48:17Z http://journalarticle.ukm.my/18063/ Alkaloid caulerpin and cytotoxic activity against NCL-H460 lung cancer cells isolated along with β-sitosterol from the Halimeda cylindracea decaisne Dini, Iwan Soekamto, Nunuk Hariani Firdaus, Supratman, Unang Jalifah Latip, Alkaloid caulerpin (1), along with β-sitosterol (2), were isolated from the n-hexane extract of the macroalga Halimeda cylindracea Decaisne. The chemical structure was identified by a spectroscopic method including IR, MS, UV, NMR 1D, NMR 2D, and comparison with data of spectra previously reported. Compounds (1) and (2) were isolated for the first time from this macroalga. Compund (1) were evaluated for their cytotoxicity activity against NCL-H460 lung cancer cells in vitro and showed moderate activity with IC50 value of 20.05 μg/mL. Penerbit Universiti Kebangsaan Malaysia 2021-09 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/18063/1/14.pdf Dini, Iwan and Soekamto, Nunuk Hariani and Firdaus, and Supratman, Unang and Jalifah Latip, (2021) Alkaloid caulerpin and cytotoxic activity against NCL-H460 lung cancer cells isolated along with β-sitosterol from the Halimeda cylindracea decaisne. Sains Malaysiana, 50 (9). pp. 2663-2674. ISSN 0126-6039 https://www.ukm.my/jsm/malay_journals/jilid50bil9_2021/KandunganJilid50Bil9_2021.html
institution Universiti Kebangsaan Malaysia
building Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Alkaloid caulerpin (1), along with β-sitosterol (2), were isolated from the n-hexane extract of the macroalga Halimeda cylindracea Decaisne. The chemical structure was identified by a spectroscopic method including IR, MS, UV, NMR 1D, NMR 2D, and comparison with data of spectra previously reported. Compounds (1) and (2) were isolated for the first time from this macroalga. Compund (1) were evaluated for their cytotoxicity activity against NCL-H460 lung cancer cells in vitro and showed moderate activity with IC50 value of 20.05 μg/mL.
format Article
author Dini, Iwan
Soekamto, Nunuk Hariani
Firdaus,
Supratman, Unang
Jalifah Latip,
spellingShingle Dini, Iwan
Soekamto, Nunuk Hariani
Firdaus,
Supratman, Unang
Jalifah Latip,
Alkaloid caulerpin and cytotoxic activity against NCL-H460 lung cancer cells isolated along with β-sitosterol from the Halimeda cylindracea decaisne
author_facet Dini, Iwan
Soekamto, Nunuk Hariani
Firdaus,
Supratman, Unang
Jalifah Latip,
author_sort Dini, Iwan
title Alkaloid caulerpin and cytotoxic activity against NCL-H460 lung cancer cells isolated along with β-sitosterol from the Halimeda cylindracea decaisne
title_short Alkaloid caulerpin and cytotoxic activity against NCL-H460 lung cancer cells isolated along with β-sitosterol from the Halimeda cylindracea decaisne
title_full Alkaloid caulerpin and cytotoxic activity against NCL-H460 lung cancer cells isolated along with β-sitosterol from the Halimeda cylindracea decaisne
title_fullStr Alkaloid caulerpin and cytotoxic activity against NCL-H460 lung cancer cells isolated along with β-sitosterol from the Halimeda cylindracea decaisne
title_full_unstemmed Alkaloid caulerpin and cytotoxic activity against NCL-H460 lung cancer cells isolated along with β-sitosterol from the Halimeda cylindracea decaisne
title_sort alkaloid caulerpin and cytotoxic activity against ncl-h460 lung cancer cells isolated along with β-sitosterol from the halimeda cylindracea decaisne
publisher Penerbit Universiti Kebangsaan Malaysia
publishDate 2021
url http://journalarticle.ukm.my/18063/1/14.pdf
http://journalarticle.ukm.my/18063/
https://www.ukm.my/jsm/malay_journals/jilid50bil9_2021/KandunganJilid50Bil9_2021.html
_version_ 1725973505620574208
score 13.211869

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