Cover Image

Tualang honey supplementation improves inflammatory and bone markers among postmenopausal breast cancer patients : a randomised controlled trial

Honey is traditionally used among breast cancer patients in Malaysia with the belief that it can improve the overall health. Therefore, this study aims to determine the effects of Tualang honey supplementation on levels of inflammatory markers, bone markers and oestradiol among postmenopausal breast...

Full description

Saved in:
Bibliographic Details
Main Authors: Zaida Zakaria,, Wan Zuraida Wan Ab Hamid,, Mahaneem Mohamed,
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2021
Online Access:http://journalarticle.ukm.my/17558/1/12.pdf
http://journalarticle.ukm.my/17558/
https://www.ukm.my/jsm/malay_journals/jilid50bil7_2021/KandunganJilid50Bil7_2021.html
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-ukm.journal.17558
record_format eprints
spelling my-ukm.journal.175582021-11-15T02:00:44Z http://journalarticle.ukm.my/17558/ Tualang honey supplementation improves inflammatory and bone markers among postmenopausal breast cancer patients : a randomised controlled trial Zaida Zakaria, Wan Zuraida Wan Ab Hamid, Mahaneem Mohamed, Honey is traditionally used among breast cancer patients in Malaysia with the belief that it can improve the overall health. Therefore, this study aims to determine the effects of Tualang honey supplementation on levels of inflammatory markers, bone markers and oestradiol among postmenopausal breast cancer patients. Seventy-two patients on anastrozole were recruited and randomly divided into two groups (n = 36/group, with or without 20 g/day of Tualang honey for 12 weeks). Levels of interleukin-1 beta (IL-1β), tumour necrosis factor alpha (TNF-α) and carboxy-terminal crosslinked telopeptide of type 1 collagen (CTX) at post-intervention with anastrozole, increased significantly compared to their corresponding levels at pre-intervention. Meanwhile, at post-intervention with anastrozole+honey, procollagen type 1 amino-terminal propeptide level increased significantly, CTX level decreased significantly, with no change in inflammatory markers compared to their pre-intervention levels. In conclusion, Tualang honey supplementation prevented the increased inflammation, reduced bone resorption and increased bone formation without changes in oestradiol level. Penerbit Universiti Kebangsaan Malaysia 2021-07 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/17558/1/12.pdf Zaida Zakaria, and Wan Zuraida Wan Ab Hamid, and Mahaneem Mohamed, (2021) Tualang honey supplementation improves inflammatory and bone markers among postmenopausal breast cancer patients : a randomised controlled trial. Sains Malaysiana, 50 (7). pp. 1971-1985. ISSN 0126-6039 https://www.ukm.my/jsm/malay_journals/jilid50bil7_2021/KandunganJilid50Bil7_2021.html
institution Universiti Kebangsaan Malaysia
building Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Honey is traditionally used among breast cancer patients in Malaysia with the belief that it can improve the overall health. Therefore, this study aims to determine the effects of Tualang honey supplementation on levels of inflammatory markers, bone markers and oestradiol among postmenopausal breast cancer patients. Seventy-two patients on anastrozole were recruited and randomly divided into two groups (n = 36/group, with or without 20 g/day of Tualang honey for 12 weeks). Levels of interleukin-1 beta (IL-1β), tumour necrosis factor alpha (TNF-α) and carboxy-terminal crosslinked telopeptide of type 1 collagen (CTX) at post-intervention with anastrozole, increased significantly compared to their corresponding levels at pre-intervention. Meanwhile, at post-intervention with anastrozole+honey, procollagen type 1 amino-terminal propeptide level increased significantly, CTX level decreased significantly, with no change in inflammatory markers compared to their pre-intervention levels. In conclusion, Tualang honey supplementation prevented the increased inflammation, reduced bone resorption and increased bone formation without changes in oestradiol level.
format Article
author Zaida Zakaria,
Wan Zuraida Wan Ab Hamid,
Mahaneem Mohamed,
spellingShingle Zaida Zakaria,
Wan Zuraida Wan Ab Hamid,
Mahaneem Mohamed,
Tualang honey supplementation improves inflammatory and bone markers among postmenopausal breast cancer patients : a randomised controlled trial
author_facet Zaida Zakaria,
Wan Zuraida Wan Ab Hamid,
Mahaneem Mohamed,
author_sort Zaida Zakaria,
title Tualang honey supplementation improves inflammatory and bone markers among postmenopausal breast cancer patients : a randomised controlled trial
title_short Tualang honey supplementation improves inflammatory and bone markers among postmenopausal breast cancer patients : a randomised controlled trial
title_full Tualang honey supplementation improves inflammatory and bone markers among postmenopausal breast cancer patients : a randomised controlled trial
title_fullStr Tualang honey supplementation improves inflammatory and bone markers among postmenopausal breast cancer patients : a randomised controlled trial
title_full_unstemmed Tualang honey supplementation improves inflammatory and bone markers among postmenopausal breast cancer patients : a randomised controlled trial
title_sort tualang honey supplementation improves inflammatory and bone markers among postmenopausal breast cancer patients : a randomised controlled trial
publisher Penerbit Universiti Kebangsaan Malaysia
publishDate 2021
url http://journalarticle.ukm.my/17558/1/12.pdf
http://journalarticle.ukm.my/17558/
https://www.ukm.my/jsm/malay_journals/jilid50bil7_2021/KandunganJilid50Bil7_2021.html
_version_ 1717094736483844096
score 13.211869

Similar Items