Staff View: Local anesthesia systemic toxicity (LAST) treated as anaphylaxis

Local anesthesia systemic toxicity (LAST) treated as anaphylaxis

Local anesthesia systemic toxicity (LAST) and anaphylaxis are the life-threatening adverse effects of lignocaine. Both have different presentations and treatments. We report a case of 35-year-old female who came to our Emergency Department (ED) with symptoms of lethargy, drowsiness, and diffic...

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Main Authors:	Amirudin Sanip,, Ismail MS,
Format:	Article
Language:	English
Published:	Pusat Perubatan Universiti Kebangsaan Malaysia 2021
Online Access:	http://journalarticle.ukm.my/17455/1/24_ms0402_pdf_17197.pdf http://journalarticle.ukm.my/17455/ https://www.medicineandhealthukm.com/toc/16/1
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id	my-ukm.journal.17455
record_format	eprints
spelling	my-ukm.journal.174552021-09-23T04:15:33Z http://journalarticle.ukm.my/17455/ Local anesthesia systemic toxicity (LAST) treated as anaphylaxis Amirudin Sanip, Ismail MS, Local anesthesia systemic toxicity (LAST) and anaphylaxis are the life-threatening adverse effects of lignocaine. Both have different presentations and treatments. We report a case of 35-year-old female who came to our Emergency Department (ED) with symptoms of lethargy, drowsiness, and difficulty breathing with foreign body sensation and a metallic taste in the throat which started 15 minutes after a right shoulder injection with 250 mg of lignocaine mixed with Triamcinolone in the Orthopedic Clinic. She was pushed to the resuscitation bay and was treated as anaphylaxis. Upon further evaluation, the blood pressure was never hypotensive, no sign of compromised airway, no gastrointestinal symptom, and no mucosal involvement which directs to the diagnosis of LAST rather than anaphylaxis. Surprisingly, she was gradually improving and was discharged home after six hours of observation in the ED. This is the first case report that LAST had been effectively treated as anaphylaxis. Pusat Perubatan Universiti Kebangsaan Malaysia 2021-06 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/17455/1/24_ms0402_pdf_17197.pdf Amirudin Sanip, and Ismail MS, (2021) Local anesthesia systemic toxicity (LAST) treated as anaphylaxis. Medicine & Health, 16 (1). pp. 277-282. ISSN 2289-5728 https://www.medicineandhealthukm.com/toc/16/1
institution	Universiti Kebangsaan Malaysia
building	Tun Sri Lanang Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Kebangsaan Malaysia
content_source	UKM Journal Article Repository
url_provider	http://journalarticle.ukm.my/
language	English
description	Local anesthesia systemic toxicity (LAST) and anaphylaxis are the life-threatening adverse effects of lignocaine. Both have different presentations and treatments. We report a case of 35-year-old female who came to our Emergency Department (ED) with symptoms of lethargy, drowsiness, and difficulty breathing with foreign body sensation and a metallic taste in the throat which started 15 minutes after a right shoulder injection with 250 mg of lignocaine mixed with Triamcinolone in the Orthopedic Clinic. She was pushed to the resuscitation bay and was treated as anaphylaxis. Upon further evaluation, the blood pressure was never hypotensive, no sign of compromised airway, no gastrointestinal symptom, and no mucosal involvement which directs to the diagnosis of LAST rather than anaphylaxis. Surprisingly, she was gradually improving and was discharged home after six hours of observation in the ED. This is the first case report that LAST had been effectively treated as anaphylaxis.
format	Article
author	Amirudin Sanip, Ismail MS,
spellingShingle	Amirudin Sanip, Ismail MS, Local anesthesia systemic toxicity (LAST) treated as anaphylaxis
author_facet	Amirudin Sanip, Ismail MS,
author_sort	Amirudin Sanip,
title	Local anesthesia systemic toxicity (LAST) treated as anaphylaxis
title_short	Local anesthesia systemic toxicity (LAST) treated as anaphylaxis
title_full	Local anesthesia systemic toxicity (LAST) treated as anaphylaxis
title_fullStr	Local anesthesia systemic toxicity (LAST) treated as anaphylaxis
title_full_unstemmed	Local anesthesia systemic toxicity (LAST) treated as anaphylaxis
title_sort	local anesthesia systemic toxicity (last) treated as anaphylaxis
publisher	Pusat Perubatan Universiti Kebangsaan Malaysia
publishDate	2021
url	http://journalarticle.ukm.my/17455/1/24_ms0402_pdf_17197.pdf http://journalarticle.ukm.my/17455/ https://www.medicineandhealthukm.com/toc/16/1
_version_	1712286243598893056
score	13.211869

Local anesthesia systemic toxicity (LAST) treated as anaphylaxis

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