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Determinants of pertussis among young children in Selangor, Malaysia

The resurgence of pertussis infection worldwide, including Malaysia, is alarming. Young children have the highest reported pertussis incidence and death rates. However, little is known of the risk factors of pertussis in Malaysia. In this study, we aimed to determine the risk factors of pertussis in...

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Main Authors: Juliana Mansor,, Halim Ismail,, Noriah Ismail,
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2021
Online Access:http://journalarticle.ukm.my/16502/1/15.pdf
http://journalarticle.ukm.my/16502/
https://www.ukm.my/jsm/malay_journals/jilid50bil2_2021/KandunganJilid50Bil2_2021.html
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spelling my-ukm.journal.165022021-04-28T07:04:16Z http://journalarticle.ukm.my/16502/ Determinants of pertussis among young children in Selangor, Malaysia Juliana Mansor, Halim Ismail, Noriah Ismail, The resurgence of pertussis infection worldwide, including Malaysia, is alarming. Young children have the highest reported pertussis incidence and death rates. However, little is known of the risk factors of pertussis in Malaysia. In this study, we aimed to determine the risk factors of pertussis infection among children. We conducted a case-control study involving 143 children aged ≤2 years from Selangor, Malaysia. The children were identified from eNotifikasi, a web-based notification site, from 1 January to 31 December, 2018. Information on clinical presentation and risk factors were collected during investigation of the case by the district health office. Multivariate analysis showed that the odds for pertussis were higher among children aged <3 months (adjusted odds ratio (aOR) 5.54; 95% confidence interval (CI); 1.835, 16.710) and among children who had not received their vaccination according to age (aOR 5.641; 95% CI; 1.845, 17.245). The mean duration of cough among the cases was 10.22 days (SD 8.964); that of the controls was 6.47 days (SD 7.098). Paroxysmal cough (93.6%) was the predominant symptom among the cases. A total of 42.6% of cases were aged <2 months, whilst most of the controls were aged >5 months (40.4%). Up to 42.6% of cases and 68.7% of controls were immunised according to their age. Therefore, it is important to ensure that children are vaccinated once they have attained the appropriate age. Penerbit Universiti Kebangsaan Malaysia 2021-02 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/16502/1/15.pdf Juliana Mansor, and Halim Ismail, and Noriah Ismail, (2021) Determinants of pertussis among young children in Selangor, Malaysia. Sains Malaysiana, 50 (2). pp. 437-447. ISSN 0126-6039 https://www.ukm.my/jsm/malay_journals/jilid50bil2_2021/KandunganJilid50Bil2_2021.html
institution Universiti Kebangsaan Malaysia
building Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description The resurgence of pertussis infection worldwide, including Malaysia, is alarming. Young children have the highest reported pertussis incidence and death rates. However, little is known of the risk factors of pertussis in Malaysia. In this study, we aimed to determine the risk factors of pertussis infection among children. We conducted a case-control study involving 143 children aged ≤2 years from Selangor, Malaysia. The children were identified from eNotifikasi, a web-based notification site, from 1 January to 31 December, 2018. Information on clinical presentation and risk factors were collected during investigation of the case by the district health office. Multivariate analysis showed that the odds for pertussis were higher among children aged <3 months (adjusted odds ratio (aOR) 5.54; 95% confidence interval (CI); 1.835, 16.710) and among children who had not received their vaccination according to age (aOR 5.641; 95% CI; 1.845, 17.245). The mean duration of cough among the cases was 10.22 days (SD 8.964); that of the controls was 6.47 days (SD 7.098). Paroxysmal cough (93.6%) was the predominant symptom among the cases. A total of 42.6% of cases were aged <2 months, whilst most of the controls were aged >5 months (40.4%). Up to 42.6% of cases and 68.7% of controls were immunised according to their age. Therefore, it is important to ensure that children are vaccinated once they have attained the appropriate age.
format Article
author Juliana Mansor,
Halim Ismail,
Noriah Ismail,
spellingShingle Juliana Mansor,
Halim Ismail,
Noriah Ismail,
Determinants of pertussis among young children in Selangor, Malaysia
author_facet Juliana Mansor,
Halim Ismail,
Noriah Ismail,
author_sort Juliana Mansor,
title Determinants of pertussis among young children in Selangor, Malaysia
title_short Determinants of pertussis among young children in Selangor, Malaysia
title_full Determinants of pertussis among young children in Selangor, Malaysia
title_fullStr Determinants of pertussis among young children in Selangor, Malaysia
title_full_unstemmed Determinants of pertussis among young children in Selangor, Malaysia
title_sort determinants of pertussis among young children in selangor, malaysia
publisher Penerbit Universiti Kebangsaan Malaysia
publishDate 2021
url http://journalarticle.ukm.my/16502/1/15.pdf
http://journalarticle.ukm.my/16502/
https://www.ukm.my/jsm/malay_journals/jilid50bil2_2021/KandunganJilid50Bil2_2021.html
_version_ 1698697939134709760
score 13.211869

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