Defining the prevalence and predictors of restrictive and obstructive airway pattern in a non-selected Malaysian population
The incidence of chronic obstructive pulmonary disease (COPD) in Malaysia appear to be increasing. To date, there are no local studies describing restrictive and obstructive airflow limitation patterns using spirometry. We conducted a cross�sectional study to determine the prevalence and predict...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pusat Perubatan Universiti Kebangsaan Malaysia
2020
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| Online Access: | http://journalarticle.ukm.my/16276/1/14_ms0422_pdf_21957.pdf http://journalarticle.ukm.my/16276/ https://www.medicineandhealthukm.com/toc/15/2 |
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| Summary: | The incidence of chronic obstructive pulmonary disease (COPD) in Malaysia
appear to be increasing. To date, there are no local studies describing restrictive
and obstructive airflow limitation patterns using spirometry. We conducted a cross�sectional study to determine the prevalence and predictors of airflow limitation
symptoms by screening for COPD symptoms with the COPD Population Screener
(COPD-PS) questionnaire and determined the airflow limitation using the new
hand-held device, AirSmart®. We recruited 265 subjects. Eleven percent had
restrictive pattern and 16% had obstructive pattern. Twenty percent of subjects
had COPD-PS score of more than five. In the obstructive pattern group, 74% were
active or ex-smokers (p=0.03, p<0.01), whilst those with restrictive pattern were
more likely to be heavier with a body mass index (BMI) of more than 23 (OR 2.52,
95% CI: 1.02-5.62) (p<0.01). There was a negative correlation between forced vital
capacity and BMI (r=-0.5813, p<0.001). We found a high prevalence restrictive
pattern of airflow limitation using the new AirSmart® Spirometer. There appeared
to be a large proportion of undiagnosed obstructive airway diseases and higher
BMI could be the causes of limitation of airflow in our subjects. |
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