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Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome

Post-infectious bronchiolitis obliterans is a rare disease that may occur following a microbiological insult towards the lower respiratory tract causing a severe form of chronic obstructive airway disease. Subpleural lung cyst may occur in 20-36% of Down syndrome. We report a case of a 30-month-old...

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Main Authors: Nurdiyana N,, Faizah MZ,, Hasniah Abdul Latif,
Format: Article
Language:English
Published: Pusat Perubatan Universiti Kebangsaan Malaysia 2019
Online Access:http://journalarticle.ukm.my/15233/1/25_ms0277_pdf_81634.pdf
http://journalarticle.ukm.my/15233/
http://www.medicineandhealthukm.com/toc/14/1
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spelling my-ukm.journal.152332020-09-21T07:02:26Z http://journalarticle.ukm.my/15233/ Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome Nurdiyana N, Faizah MZ, Hasniah Abdul Latif, Post-infectious bronchiolitis obliterans is a rare disease that may occur following a microbiological insult towards the lower respiratory tract causing a severe form of chronic obstructive airway disease. Subpleural lung cyst may occur in 20-36% of Down syndrome. We report a case of a 30-month-old Down syndrome child who had interesting radiological concurrent findings of bronchiolitis obliterans with subpleural cysts on High Resolution Computed Tomography (HRCT) thorax. This patient was born premature and had early onset pneumonia during the neonatal period. Subsequently, he had three episodes of pneumonias at 18, 19 and 26 months. He presented with recurrent symptoms of cough, wheeze, rapid breathing and had features of persistent airway obstruction characterized by chest hyperinflation, persistent tachypnoea with crepitations and rhonchi despite on regular bronchodilators. The only positive culture was Influenza B from his nasopharyneal aspirate culture. To our knowledge, this is the first reported case with both radiological entities in a child with Down syndrome. Pusat Perubatan Universiti Kebangsaan Malaysia 2019 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/15233/1/25_ms0277_pdf_81634.pdf Nurdiyana N, and Faizah MZ, and Hasniah Abdul Latif, (2019) Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome. Medicine & Health, 14 (1). pp. 252-258. ISSN 2289-5728 http://www.medicineandhealthukm.com/toc/14/1
institution Universiti Kebangsaan Malaysia
building Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Post-infectious bronchiolitis obliterans is a rare disease that may occur following a microbiological insult towards the lower respiratory tract causing a severe form of chronic obstructive airway disease. Subpleural lung cyst may occur in 20-36% of Down syndrome. We report a case of a 30-month-old Down syndrome child who had interesting radiological concurrent findings of bronchiolitis obliterans with subpleural cysts on High Resolution Computed Tomography (HRCT) thorax. This patient was born premature and had early onset pneumonia during the neonatal period. Subsequently, he had three episodes of pneumonias at 18, 19 and 26 months. He presented with recurrent symptoms of cough, wheeze, rapid breathing and had features of persistent airway obstruction characterized by chest hyperinflation, persistent tachypnoea with crepitations and rhonchi despite on regular bronchodilators. The only positive culture was Influenza B from his nasopharyneal aspirate culture. To our knowledge, this is the first reported case with both radiological entities in a child with Down syndrome.
format Article
author Nurdiyana N,
Faizah MZ,
Hasniah Abdul Latif,
spellingShingle Nurdiyana N,
Faizah MZ,
Hasniah Abdul Latif,
Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome
author_facet Nurdiyana N,
Faizah MZ,
Hasniah Abdul Latif,
author_sort Nurdiyana N,
title Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome
title_short Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome
title_full Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome
title_fullStr Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome
title_full_unstemmed Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome
title_sort post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome
publisher Pusat Perubatan Universiti Kebangsaan Malaysia
publishDate 2019
url http://journalarticle.ukm.my/15233/1/25_ms0277_pdf_81634.pdf
http://journalarticle.ukm.my/15233/
http://www.medicineandhealthukm.com/toc/14/1
_version_ 1678593699702898688
score 13.211869

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