Cover Image

Brain activations evoked by passive and active listening: a preliminary study on multiple subjects

A functional magnetic resonance imaging (fMRI) study was conducted on 4 healthy male and female subjects to investigate brain activation during passive and active listening. Two different experimental conditions were separately used in this study. The first condition requires the subjects to list...

Full description

Saved in:
Bibliographic Details
Main Authors: Ahmad Nazlim Yusoff,, Mazlyfarina Mohamad,, Mohd Mahadir Ayob,, Mohd Harith Hashim,
Format: Article
Language:English
Published: Penerbit UKM 2008
Online Access:http://journalarticle.ukm.my/1403/1/Ahmad%20Nazlim%20Yusoff%20et%20al..pdf
http://journalarticle.ukm.my/1403/
http://www.fskb.ukm.my/fskbold/jurnal.html
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-ukm.journal.1403
record_format eprints
spelling my-ukm.journal.14032016-12-14T06:29:24Z http://journalarticle.ukm.my/1403/ Brain activations evoked by passive and active listening: a preliminary study on multiple subjects Ahmad Nazlim Yusoff, Mazlyfarina Mohamad, Mohd Mahadir Ayob, Mohd Harith Hashim, A functional magnetic resonance imaging (fMRI) study was conducted on 4 healthy male and female subjects to investigate brain activation during passive and active listening. Two different experimental conditions were separately used in this study. The first condition requires the subjects to listen to a simple arithmetic instruction (e.g. one-plus-two-plus-three-plus-four) – passive listening. In the second condition, the subjects were given the same series of arithmetic instruction and were required to listen and perform the calculation – active listening. The data were then analysed using the Statistical Parametric Mapping (SPM5) and the MATLAB 7.4 (R2007a) programming softwares. The results obtained from the fixed (FFX) and random effects analyses (RFX) show that the active-state signal intensity was significantly higher (p < 0.05) than the resting-state signal intensity for both conditions. The results also indicate significant differences (p < 0.001) in brain activation between passive and active listening. The activated cortical regions during passive listening, as obtained from the FFX of the first condition is symmetrical in the left and right temporal and frontal lobes covering the cortical auditory areas. However, for the second condition, which was active listening, more activation occurs in the left hemisphere with a reduction in the number of activated voxels and their signal intensity in the right hemisphere. Activation mainly occurs in the middle temporal gyrus, precentral gyrus, middle frontal gyrus, superior temporal gyrus and several other areas in the frontal lobes. The point of maximum signal intensity has been shifted to a new coordinates during active listening. It is also observed that the magnetic resonance signal intensity and the number of activated voxel in the right and left superior temporal lobes for the second condition have been reduced as compared to that of the first condition. The results obtained strongly suggest the existence of functional specialisation. The results also indicate different networks for the two conditions. These networks clearly pertain to the existence of functional Jurnal Sains Kesihatan Malaysia 6 (1) 2008: 35-6036 connectivity between activation areas during listening and listening while performing a simple arithmetic task. Penerbit UKM 2008-06 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/1403/1/Ahmad%20Nazlim%20Yusoff%20et%20al..pdf Ahmad Nazlim Yusoff, and Mazlyfarina Mohamad, and Mohd Mahadir Ayob, and Mohd Harith Hashim, (2008) Brain activations evoked by passive and active listening: a preliminary study on multiple subjects. Jurnal Sains Kesihatan Malaysia, 6 (1). pp. 35-60. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold/jurnal.html
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description A functional magnetic resonance imaging (fMRI) study was conducted on 4 healthy male and female subjects to investigate brain activation during passive and active listening. Two different experimental conditions were separately used in this study. The first condition requires the subjects to listen to a simple arithmetic instruction (e.g. one-plus-two-plus-three-plus-four) – passive listening. In the second condition, the subjects were given the same series of arithmetic instruction and were required to listen and perform the calculation – active listening. The data were then analysed using the Statistical Parametric Mapping (SPM5) and the MATLAB 7.4 (R2007a) programming softwares. The results obtained from the fixed (FFX) and random effects analyses (RFX) show that the active-state signal intensity was significantly higher (p < 0.05) than the resting-state signal intensity for both conditions. The results also indicate significant differences (p < 0.001) in brain activation between passive and active listening. The activated cortical regions during passive listening, as obtained from the FFX of the first condition is symmetrical in the left and right temporal and frontal lobes covering the cortical auditory areas. However, for the second condition, which was active listening, more activation occurs in the left hemisphere with a reduction in the number of activated voxels and their signal intensity in the right hemisphere. Activation mainly occurs in the middle temporal gyrus, precentral gyrus, middle frontal gyrus, superior temporal gyrus and several other areas in the frontal lobes. The point of maximum signal intensity has been shifted to a new coordinates during active listening. It is also observed that the magnetic resonance signal intensity and the number of activated voxel in the right and left superior temporal lobes for the second condition have been reduced as compared to that of the first condition. The results obtained strongly suggest the existence of functional specialisation. The results also indicate different networks for the two conditions. These networks clearly pertain to the existence of functional Jurnal Sains Kesihatan Malaysia 6 (1) 2008: 35-6036 connectivity between activation areas during listening and listening while performing a simple arithmetic task.
format Article
author Ahmad Nazlim Yusoff,
Mazlyfarina Mohamad,
Mohd Mahadir Ayob,
Mohd Harith Hashim,
spellingShingle Ahmad Nazlim Yusoff,
Mazlyfarina Mohamad,
Mohd Mahadir Ayob,
Mohd Harith Hashim,
Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
author_facet Ahmad Nazlim Yusoff,
Mazlyfarina Mohamad,
Mohd Mahadir Ayob,
Mohd Harith Hashim,
author_sort Ahmad Nazlim Yusoff,
title Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
title_short Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
title_full Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
title_fullStr Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
title_full_unstemmed Brain activations evoked by passive and active listening: a preliminary study on multiple subjects
title_sort brain activations evoked by passive and active listening: a preliminary study on multiple subjects
publisher Penerbit UKM
publishDate 2008
url http://journalarticle.ukm.my/1403/1/Ahmad%20Nazlim%20Yusoff%20et%20al..pdf
http://journalarticle.ukm.my/1403/
http://www.fskb.ukm.my/fskbold/jurnal.html
_version_ 1643735009206468608
score 13.223943

Similar Items