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Coconut-water as fermentation medium for enzyme production (4): Time-profiled control of batch 5L stirred tank fermentation

The use of coconut-water as a cheap fermentation medium for the production of the enzyme cytochrome p-450 by the yeast Saccharomyces cerevisiae N.C.Y.C 754 was investigated in a 5L stirred tank fermenter by building state variable models and generating optimum control time-profiles for the contro...

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Main Authors: Jailani Salihon,, Ahmad Jaril Asis,, Siti Masrinda Tasirin,
Format: Article
Published: 1995
Online Access:http://journalarticle.ukm.my/1320/
http://www.ukm.my/jkukm/index.php/jkukm
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spelling my-ukm.journal.13202011-10-11T03:45:14Z http://journalarticle.ukm.my/1320/ Coconut-water as fermentation medium for enzyme production (4): Time-profiled control of batch 5L stirred tank fermentation Jailani Salihon, Ahmad Jaril Asis, Siti Masrinda Tasirin, The use of coconut-water as a cheap fermentation medium for the production of the enzyme cytochrome p-450 by the yeast Saccharomyces cerevisiae N.C.Y.C 754 was investigated in a 5L stirred tank fermenter by building state variable models and generating optimum control time-profiles for the control variables temperature (T), pH and agitation rate (RPM) Using Pontryagin's Continuous Maximum Principle. The theoretical maximum enzyme yield that can be achieved under optimum timeprofiled control of the three variables is 694.87 nmol L-1 in 30.5 hours of fermentation. Except for T, the continuous optimum time-profiles of the variables do not differ significantly from that of set point control. Experiments conducted with the three variables controlled along these time-profiles gave an average yield of 633.70 nmol L-1 in 28 hours of fermentation 1995 Article PeerReviewed Jailani Salihon, and Ahmad Jaril Asis, and Siti Masrinda Tasirin, (1995) Coconut-water as fermentation medium for enzyme production (4): Time-profiled control of batch 5L stirred tank fermentation. Jurnal Kejuruteraan, 7 . http://www.ukm.my/jkukm/index.php/jkukm
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
description The use of coconut-water as a cheap fermentation medium for the production of the enzyme cytochrome p-450 by the yeast Saccharomyces cerevisiae N.C.Y.C 754 was investigated in a 5L stirred tank fermenter by building state variable models and generating optimum control time-profiles for the control variables temperature (T), pH and agitation rate (RPM) Using Pontryagin's Continuous Maximum Principle. The theoretical maximum enzyme yield that can be achieved under optimum timeprofiled control of the three variables is 694.87 nmol L-1 in 30.5 hours of fermentation. Except for T, the continuous optimum time-profiles of the variables do not differ significantly from that of set point control. Experiments conducted with the three variables controlled along these time-profiles gave an average yield of 633.70 nmol L-1 in 28 hours of fermentation
format Article
author Jailani Salihon,
Ahmad Jaril Asis,
Siti Masrinda Tasirin,
spellingShingle Jailani Salihon,
Ahmad Jaril Asis,
Siti Masrinda Tasirin,
Coconut-water as fermentation medium for enzyme production (4): Time-profiled control of batch 5L stirred tank fermentation
author_facet Jailani Salihon,
Ahmad Jaril Asis,
Siti Masrinda Tasirin,
author_sort Jailani Salihon,
title Coconut-water as fermentation medium for enzyme production (4): Time-profiled control of batch 5L stirred tank fermentation
title_short Coconut-water as fermentation medium for enzyme production (4): Time-profiled control of batch 5L stirred tank fermentation
title_full Coconut-water as fermentation medium for enzyme production (4): Time-profiled control of batch 5L stirred tank fermentation
title_fullStr Coconut-water as fermentation medium for enzyme production (4): Time-profiled control of batch 5L stirred tank fermentation
title_full_unstemmed Coconut-water as fermentation medium for enzyme production (4): Time-profiled control of batch 5L stirred tank fermentation
title_sort coconut-water as fermentation medium for enzyme production (4): time-profiled control of batch 5l stirred tank fermentation
publishDate 1995
url http://journalarticle.ukm.my/1320/
http://www.ukm.my/jkukm/index.php/jkukm
_version_ 1643734979732045824
score 13.211869

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