Ameliorating effects of coconut water on sperm quality and selected organs histology in monosodium glutamate pre treated male mice (Mus musculus)
This study was conducted to determine the effect of both monosodium glutamate (MSG) and coconut water on sperm quality of Mus musculus. Twenty adult mice weighing between 25-30 g were randomly divided into four groups. Group A (Control), received saline solution; Group B received 2 g/kg b.wt of MS...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2017
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| Online Access: | http://journalarticle.ukm.my/12298/1/46_01_05.pdf http://journalarticle.ukm.my/12298/ http://www.mabjournal.com/index.php?option=com_content&view=article&id=623&catid=59:current-view&Itemid=56 |
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| Summary: | This study was conducted to determine the effect of both monosodium glutamate (MSG) and coconut water on sperm quality
of Mus musculus. Twenty adult mice weighing between 25-30 g were randomly divided into four groups. Group A (Control),
received saline solution; Group B received 2 g/kg b.wt of MSG; Group C received administration of both coconut water (10
mL/kg b.wt) and MSG (2 g/kg b.wt); and Group D was given coconut water (10 mL/kg b.wt) only. Treatments were given
daily for a duration of 15 days. Results revealed the MSG treated group showed a significant reduction (p<0.05) in sperm
concentration, motile sperm, and viable sperm with values 23×106/ml, 19.59%, and 16%, respectively. Group C which received
both of MSG and coconut water showed significant improvement (p<0.05) in sperm concentration, motile sperm, and viable
sperm which were 47.4×106/ml, 66.69%, and 30.6%, respectively. Several histological alterations were observed in the testes
of MSG treated mice. However, the co-administration of MSG and coconut water was proven to be beneficial for the
improvement of sperm concentration, motility, and viability. Also, coconut water group showed improved architectures of
testes compared to the MSG treated mice. In conclusion, MSG had severely affected sperm quality but co-administration of
both coconut water and MSG had indicated ameliorating effects of coconut water towards its negative impact. |
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