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Surface modification of cellulose nanomaterial for urea biosensor application

Cellulose nanomaterial with rod-like structure and highly crystalline order, usually formed by elimination of the amorphous region from cellulose during acid hydrolysis. Cellulose nanomaterial with the property of biocompatibility and nontoxicity can be used for enzyme immobilization. In this work,...

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Main Authors: Wan Elina Faradilla Wan Khalid,, Lee, Yook Heng, Mohamad Nasir Mat Arip,
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2018
Online Access:http://journalarticle.ukm.my/12082/1/09%20Wan%20Elina%20Faradilla.pdf
http://journalarticle.ukm.my/12082/
http://www.ukm.my/jsm/english_journals/vol47num5_2018/contentsVol47num5_2018.html
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spelling my-ukm.journal.120822018-09-22T10:42:36Z http://journalarticle.ukm.my/12082/ Surface modification of cellulose nanomaterial for urea biosensor application Wan Elina Faradilla Wan Khalid, Lee, Yook Heng Mohamad Nasir Mat Arip, Cellulose nanomaterial with rod-like structure and highly crystalline order, usually formed by elimination of the amorphous region from cellulose during acid hydrolysis. Cellulose nanomaterial with the property of biocompatibility and nontoxicity can be used for enzyme immobilization. In this work, urease enzyme was used as a model enzyme to study the surface modification of cellulose nanomaterial and its potential for biosensor application. The cellulose nanocrystal (CNC) surface was modified using 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation to introduce the carboxyl group at C6 primary alcohol. The success of enzyme immobilization and surface modification was confirmed using chemical tests and measured using UV-Visible spectrophotometer. The immobilization strategy was then applied for biosensor application for urea detection. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques were used for electroanalytical characterization of the urea biosensor. Penerbit Universiti Kebangsaan Malaysia 2018-05 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/12082/1/09%20Wan%20Elina%20Faradilla.pdf Wan Elina Faradilla Wan Khalid, and Lee, Yook Heng and Mohamad Nasir Mat Arip, (2018) Surface modification of cellulose nanomaterial for urea biosensor application. Sains Malaysiana, 47 (5). pp. 941-949. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol47num5_2018/contentsVol47num5_2018.html
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Cellulose nanomaterial with rod-like structure and highly crystalline order, usually formed by elimination of the amorphous region from cellulose during acid hydrolysis. Cellulose nanomaterial with the property of biocompatibility and nontoxicity can be used for enzyme immobilization. In this work, urease enzyme was used as a model enzyme to study the surface modification of cellulose nanomaterial and its potential for biosensor application. The cellulose nanocrystal (CNC) surface was modified using 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidation to introduce the carboxyl group at C6 primary alcohol. The success of enzyme immobilization and surface modification was confirmed using chemical tests and measured using UV-Visible spectrophotometer. The immobilization strategy was then applied for biosensor application for urea detection. Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques were used for electroanalytical characterization of the urea biosensor.
format Article
author Wan Elina Faradilla Wan Khalid,
Lee, Yook Heng
Mohamad Nasir Mat Arip,
spellingShingle Wan Elina Faradilla Wan Khalid,
Lee, Yook Heng
Mohamad Nasir Mat Arip,
Surface modification of cellulose nanomaterial for urea biosensor application
author_facet Wan Elina Faradilla Wan Khalid,
Lee, Yook Heng
Mohamad Nasir Mat Arip,
author_sort Wan Elina Faradilla Wan Khalid,
title Surface modification of cellulose nanomaterial for urea biosensor application
title_short Surface modification of cellulose nanomaterial for urea biosensor application
title_full Surface modification of cellulose nanomaterial for urea biosensor application
title_fullStr Surface modification of cellulose nanomaterial for urea biosensor application
title_full_unstemmed Surface modification of cellulose nanomaterial for urea biosensor application
title_sort surface modification of cellulose nanomaterial for urea biosensor application
publisher Penerbit Universiti Kebangsaan Malaysia
publishDate 2018
url http://journalarticle.ukm.my/12082/1/09%20Wan%20Elina%20Faradilla.pdf
http://journalarticle.ukm.my/12082/
http://www.ukm.my/jsm/english_journals/vol47num5_2018/contentsVol47num5_2018.html
_version_ 1643738688093421568
score 13.211869

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