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Antioxidant and mutagenic activity of herbal tea prepared from Cosmos caudatus leaves at different maturity stages

Different maturity stages of Cosmos caudatus leaves have been used to prepare herbal tea were investigated for their effect on antioxidant activity and mutagenic activity. The analyses carried out were total phenolic content (TPC), total flavonoid content (TFC), ferric reducing antioxidant power (...

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Main Authors: Dian-Nashiela Fatanah,, Noriham Abdullah,, Nooraain Hashim,, Azizah Abd. Hamid,
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2018
Online Access:http://journalarticle.ukm.my/12057/1/UKM%20SAINSMalaysiana%2047%2804%29Apr%202018%2010.pdf
http://journalarticle.ukm.my/12057/
http://www.ukm.my/jsm/malay_journals/jilid47bil4_2018/KandunganJilid47Bil4_2018.htm
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spelling my-ukm.journal.120572018-09-16T23:22:00Z http://journalarticle.ukm.my/12057/ Antioxidant and mutagenic activity of herbal tea prepared from Cosmos caudatus leaves at different maturity stages Dian-Nashiela Fatanah, Noriham Abdullah, Nooraain Hashim, Azizah Abd. Hamid, Different maturity stages of Cosmos caudatus leaves have been used to prepare herbal tea were investigated for their effect on antioxidant activity and mutagenic activity. The analyses carried out were total phenolic content (TPC), total flavonoid content (TFC), ferric reducing antioxidant power (FRAP), 2-2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, β-carotene bleaching assay, oxygen radical absorbance capacity (ORAC) and Ames Salmonella mutagenicity. The results demonstrated that, C. caudatus herbal tea prepared from young leaves showed significantly highest antioxidant activity for all assays tested, followed by mixed leaves, mature leaves, old leaves and the lowest was in C. caudatus herbal tea from a commercial brand. Pearson’s correlation coefficient also demonstrated that TPC and TFC displayed a strong correlation with all antioxidant activity assays, showing that these compounds were the major contributors to the antioxidant activity in C. caudatus herbal tea. However, all studied C. caudatus herbal tea showed no mutagenic effects against Salmonella typhimurium tester strain TA98 and TA100 with and without S9 metabolic activation. Hence, it can be concluded that, different maturity stages could affect the antioxidant activity in C. caudatus herbal tea as it reduced the antioxidant activity as maturity increased, but did not give any effect on the mutagenic activity. Penerbit Universiti Kebangsaan Malaysia 2018-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/12057/1/UKM%20SAINSMalaysiana%2047%2804%29Apr%202018%2010.pdf Dian-Nashiela Fatanah, and Noriham Abdullah, and Nooraain Hashim, and Azizah Abd. Hamid, (2018) Antioxidant and mutagenic activity of herbal tea prepared from Cosmos caudatus leaves at different maturity stages. Sains Malaysiana, 47 (4). pp. 725-730. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid47bil4_2018/KandunganJilid47Bil4_2018.htm
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description Different maturity stages of Cosmos caudatus leaves have been used to prepare herbal tea were investigated for their effect on antioxidant activity and mutagenic activity. The analyses carried out were total phenolic content (TPC), total flavonoid content (TFC), ferric reducing antioxidant power (FRAP), 2-2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, β-carotene bleaching assay, oxygen radical absorbance capacity (ORAC) and Ames Salmonella mutagenicity. The results demonstrated that, C. caudatus herbal tea prepared from young leaves showed significantly highest antioxidant activity for all assays tested, followed by mixed leaves, mature leaves, old leaves and the lowest was in C. caudatus herbal tea from a commercial brand. Pearson’s correlation coefficient also demonstrated that TPC and TFC displayed a strong correlation with all antioxidant activity assays, showing that these compounds were the major contributors to the antioxidant activity in C. caudatus herbal tea. However, all studied C. caudatus herbal tea showed no mutagenic effects against Salmonella typhimurium tester strain TA98 and TA100 with and without S9 metabolic activation. Hence, it can be concluded that, different maturity stages could affect the antioxidant activity in C. caudatus herbal tea as it reduced the antioxidant activity as maturity increased, but did not give any effect on the mutagenic activity.
format Article
author Dian-Nashiela Fatanah,
Noriham Abdullah,
Nooraain Hashim,
Azizah Abd. Hamid,
spellingShingle Dian-Nashiela Fatanah,
Noriham Abdullah,
Nooraain Hashim,
Azizah Abd. Hamid,
Antioxidant and mutagenic activity of herbal tea prepared from Cosmos caudatus leaves at different maturity stages
author_facet Dian-Nashiela Fatanah,
Noriham Abdullah,
Nooraain Hashim,
Azizah Abd. Hamid,
author_sort Dian-Nashiela Fatanah,
title Antioxidant and mutagenic activity of herbal tea prepared from Cosmos caudatus leaves at different maturity stages
title_short Antioxidant and mutagenic activity of herbal tea prepared from Cosmos caudatus leaves at different maturity stages
title_full Antioxidant and mutagenic activity of herbal tea prepared from Cosmos caudatus leaves at different maturity stages
title_fullStr Antioxidant and mutagenic activity of herbal tea prepared from Cosmos caudatus leaves at different maturity stages
title_full_unstemmed Antioxidant and mutagenic activity of herbal tea prepared from Cosmos caudatus leaves at different maturity stages
title_sort antioxidant and mutagenic activity of herbal tea prepared from cosmos caudatus leaves at different maturity stages
publisher Penerbit Universiti Kebangsaan Malaysia
publishDate 2018
url http://journalarticle.ukm.my/12057/1/UKM%20SAINSMalaysiana%2047%2804%29Apr%202018%2010.pdf
http://journalarticle.ukm.my/12057/
http://www.ukm.my/jsm/malay_journals/jilid47bil4_2018/KandunganJilid47Bil4_2018.htm
_version_ 1643738681042796544
score 13.211869

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