Cover Image

Optimum dose of sea cucumber (Stichopus chloronotus) extract for wound healing

In Malaysia, sea cucumber is also known as Gamat. Among the Malays, Gamat is frequently used as a traditional or folk medicine to relieve pain, to treat wounds and burns. It is also used as a tonic to provide extra energy. Stichopus chloronotus is one of the species of sea cucumber which is found in...

Full description

Saved in:
Bibliographic Details
Main Authors: Mazliadiyana M,, Nazrun AS,, Isa Naina Mohamed,
Format: Article
Language:English
Published: Pusat Perubatan Universiti Kebangsaan Malaysia 2017
Online Access:http://journalarticle.ukm.my/11867/1/9_mazliadiyana_et_al_pdf_73379.pdf
http://journalarticle.ukm.my/11867/
http://www.medicineandhealthukm.com/toc/12/1
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-ukm.journal.11867
record_format eprints
spelling my-ukm.journal.118672018-07-10T04:27:49Z http://journalarticle.ukm.my/11867/ Optimum dose of sea cucumber (Stichopus chloronotus) extract for wound healing Mazliadiyana M, Nazrun AS, Isa Naina Mohamed, In Malaysia, sea cucumber is also known as Gamat. Among the Malays, Gamat is frequently used as a traditional or folk medicine to relieve pain, to treat wounds and burns. It is also used as a tonic to provide extra energy. Stichopus chloronotus is one of the species of sea cucumber which is found in Malaysia. An experimental study was carried out to determine the optimum dose of aqueous extract of Stichopus chloronotus on the healing of wounds in rat model. A series of concentrations 0.1%, 0.5% and 1% aqueous extract emulsifying ointment mixed with Stichopus chloronotus was applied once a day for 10 days on the excision wound model. Changes in the wound area were measured using a caliper and photographs were taken on day 1, 3, 6, 8 and 10 after the wound creation. The wound reduction rate and macroscopic observation were evaluated to determine the optimum dose concentration. Results demonstrated that percentage of wound reduction and macroscopic observation of 0.5% aqueous extract Stichopus chloronotus emulsifying ointment mixed group was significantly higher than the other groups from day 6 following wound creation. In conclusion, 0.5% aqueous extract of Stichopus chloronotus emulsifying ointment mixture demonstrated the best dose for wound healing in a rat model. Pusat Perubatan Universiti Kebangsaan Malaysia 2017 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/11867/1/9_mazliadiyana_et_al_pdf_73379.pdf Mazliadiyana M, and Nazrun AS, and Isa Naina Mohamed, (2017) Optimum dose of sea cucumber (Stichopus chloronotus) extract for wound healing. Medicine & Health, 12 (1). pp. 83-89. ISSN 2289-5728 http://www.medicineandhealthukm.com/toc/12/1
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description In Malaysia, sea cucumber is also known as Gamat. Among the Malays, Gamat is frequently used as a traditional or folk medicine to relieve pain, to treat wounds and burns. It is also used as a tonic to provide extra energy. Stichopus chloronotus is one of the species of sea cucumber which is found in Malaysia. An experimental study was carried out to determine the optimum dose of aqueous extract of Stichopus chloronotus on the healing of wounds in rat model. A series of concentrations 0.1%, 0.5% and 1% aqueous extract emulsifying ointment mixed with Stichopus chloronotus was applied once a day for 10 days on the excision wound model. Changes in the wound area were measured using a caliper and photographs were taken on day 1, 3, 6, 8 and 10 after the wound creation. The wound reduction rate and macroscopic observation were evaluated to determine the optimum dose concentration. Results demonstrated that percentage of wound reduction and macroscopic observation of 0.5% aqueous extract Stichopus chloronotus emulsifying ointment mixed group was significantly higher than the other groups from day 6 following wound creation. In conclusion, 0.5% aqueous extract of Stichopus chloronotus emulsifying ointment mixture demonstrated the best dose for wound healing in a rat model.
format Article
author Mazliadiyana M,
Nazrun AS,
Isa Naina Mohamed,
spellingShingle Mazliadiyana M,
Nazrun AS,
Isa Naina Mohamed,
Optimum dose of sea cucumber (Stichopus chloronotus) extract for wound healing
author_facet Mazliadiyana M,
Nazrun AS,
Isa Naina Mohamed,
author_sort Mazliadiyana M,
title Optimum dose of sea cucumber (Stichopus chloronotus) extract for wound healing
title_short Optimum dose of sea cucumber (Stichopus chloronotus) extract for wound healing
title_full Optimum dose of sea cucumber (Stichopus chloronotus) extract for wound healing
title_fullStr Optimum dose of sea cucumber (Stichopus chloronotus) extract for wound healing
title_full_unstemmed Optimum dose of sea cucumber (Stichopus chloronotus) extract for wound healing
title_sort optimum dose of sea cucumber (stichopus chloronotus) extract for wound healing
publisher Pusat Perubatan Universiti Kebangsaan Malaysia
publishDate 2017
url http://journalarticle.ukm.my/11867/1/9_mazliadiyana_et_al_pdf_73379.pdf
http://journalarticle.ukm.my/11867/
http://www.medicineandhealthukm.com/toc/12/1
_version_ 1643738625871970304
score 13.211869

Similar Items