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Carboxymethyl Cellulose from palm oil empty fruit bunch – their properties and use as a Film Coating Agent

This study was carried out to determine the physicochemical properties of carboxymethyl cellulose (CMC) derived from cellulose of palm oil empty fruit bunch (EFB) and its use asa film-coating agent. Samples were prepared at various concentrations and then their physicochemical properties were studi...

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Main Authors: Amin M.C.I,, Soom R.M,, Ahmad I.,, Lian H.H,
Format: Article
Language:English
Published: penerbit ukm 2006
Online Access:http://journalarticle.ukm.my/1021/1/jurnal57.pdf
http://journalarticle.ukm.my/1021/
http://www.fskb.ukm.my/fskbold/jurnal
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spelling my-ukm.journal.10212016-12-14T06:28:35Z http://journalarticle.ukm.my/1021/ Carboxymethyl Cellulose from palm oil empty fruit bunch – their properties and use as a Film Coating Agent Amin M.C.I, Soom R.M, Ahmad I., Lian H.H, This study was carried out to determine the physicochemical properties of carboxymethyl cellulose (CMC) derived from cellulose of palm oil empty fruit bunch (EFB) and its use asa film-coating agent. Samples were prepared at various concentrations and then their physicochemical properties were studied including the viscosity, pH, tensile strength of films, surface properties of the films and dissolution studies on coated tablets. CMC EFB showed lower viscosity than commercial CMC product at the concentration of 1%, 2% and 3% with the values of 44.0cp, 299.9cp, 358.9cp and 90.0cp, 689.9cp, 5569.0cp respectively. The tensile strength of the films for CMC EFB were 7.85MPa, 14.79MPa, 10.36MPa while the commercial CMC exhibited higher values of 21.72MPa, 35.14MPa and 26.9MPa at similar concentration. The scanning electron microscope showed different surface properties of the films for both of them where the commercial CMC is smoother in texture and very transparent unlike its counterpart. However, dissolution studies on paracetamol tablets coated using the samples showed no significant difference (p>0.05) in drug release profile between the two materials. Hence, CMC EFB has a greater potential to be developed as a competitive tablet-coating agent despite the differences in its physicochemical properties. penerbit ukm 2006 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/1021/1/jurnal57.pdf Amin M.C.I, and Soom R.M, and Ahmad I., and Lian H.H, (2006) Carboxymethyl Cellulose from palm oil empty fruit bunch – their properties and use as a Film Coating Agent. Jurnal Sains Kesihatan Malaysia, 4 (2). pp. 53-62. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold/jurnal
institution Universiti Kebangsaan Malaysia
building Perpustakaan Tun Sri Lanang Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Kebangsaan Malaysia
content_source UKM Journal Article Repository
url_provider http://journalarticle.ukm.my/
language English
description This study was carried out to determine the physicochemical properties of carboxymethyl cellulose (CMC) derived from cellulose of palm oil empty fruit bunch (EFB) and its use asa film-coating agent. Samples were prepared at various concentrations and then their physicochemical properties were studied including the viscosity, pH, tensile strength of films, surface properties of the films and dissolution studies on coated tablets. CMC EFB showed lower viscosity than commercial CMC product at the concentration of 1%, 2% and 3% with the values of 44.0cp, 299.9cp, 358.9cp and 90.0cp, 689.9cp, 5569.0cp respectively. The tensile strength of the films for CMC EFB were 7.85MPa, 14.79MPa, 10.36MPa while the commercial CMC exhibited higher values of 21.72MPa, 35.14MPa and 26.9MPa at similar concentration. The scanning electron microscope showed different surface properties of the films for both of them where the commercial CMC is smoother in texture and very transparent unlike its counterpart. However, dissolution studies on paracetamol tablets coated using the samples showed no significant difference (p>0.05) in drug release profile between the two materials. Hence, CMC EFB has a greater potential to be developed as a competitive tablet-coating agent despite the differences in its physicochemical properties.
format Article
author Amin M.C.I,
Soom R.M,
Ahmad I.,
Lian H.H,
spellingShingle Amin M.C.I,
Soom R.M,
Ahmad I.,
Lian H.H,
Carboxymethyl Cellulose from palm oil empty fruit bunch – their properties and use as a Film Coating Agent
author_facet Amin M.C.I,
Soom R.M,
Ahmad I.,
Lian H.H,
author_sort Amin M.C.I,
title Carboxymethyl Cellulose from palm oil empty fruit bunch – their properties and use as a Film Coating Agent
title_short Carboxymethyl Cellulose from palm oil empty fruit bunch – their properties and use as a Film Coating Agent
title_full Carboxymethyl Cellulose from palm oil empty fruit bunch – their properties and use as a Film Coating Agent
title_fullStr Carboxymethyl Cellulose from palm oil empty fruit bunch – their properties and use as a Film Coating Agent
title_full_unstemmed Carboxymethyl Cellulose from palm oil empty fruit bunch – their properties and use as a Film Coating Agent
title_sort carboxymethyl cellulose from palm oil empty fruit bunch – their properties and use as a film coating agent
publisher penerbit ukm
publishDate 2006
url http://journalarticle.ukm.my/1021/1/jurnal57.pdf
http://journalarticle.ukm.my/1021/
http://www.fskb.ukm.my/fskbold/jurnal
_version_ 1643734870611984384
score 13.211869

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