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Determination of Maximum Tolerated Dosage of Huang Lian in Mice and its Effect of Intestinal Lactobacillus Population

Huang Lian also known as Rhizoma Coptidis is a dried rhizome of Coptis chinensis which belonged to the Genus Coptis and family of Ranunculaceae. It is used to clear heat and dries Dampness in Traditional Chinese Medicine. Xiang Sha Liu Jun Zhi Tang is a formula decoction used to tonify the Spleen an...

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Main Author: Chong, Janice Lee Ching
Format: Thesis
Language:English
Published: 2015
Subjects:
R Medicine (General)
Online Access:http://eprints.intimal.edu.my/503/1/TCM%20-%2019.pdf
http://eprints.intimal.edu.my/503/
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spelling my-inti-eprints.5032016-08-29T06:48:49Z http://eprints.intimal.edu.my/503/ Determination of Maximum Tolerated Dosage of Huang Lian in Mice and its Effect of Intestinal Lactobacillus Population Chong, Janice Lee Ching R Medicine (General) Huang Lian also known as Rhizoma Coptidis is a dried rhizome of Coptis chinensis which belonged to the Genus Coptis and family of Ranunculaceae. It is used to clear heat and dries Dampness in Traditional Chinese Medicine. Xiang Sha Liu Jun Zhi Tang is a formula decoction used to tonify the Spleen and Stomach and improve the digestive functions. Lactobacillus is an anaerobic bacterium that belonged to the order of lactic acid bacteria (LAB). It is categorized as probiotics which commercially acts as a treatment for diarrhea, indigestion, urinary tract infections and enhancing immunity. Thus the objectives of this study are to determine the maximum tolerated dosage of Huang Lian in mice and analyses its impact on Lactobacillus population with and without XSLJZT. In this experiment, 35 mice are divided into 7 groups with 5 mice each group. Three groups received Huang Lian with the dosage raging from 65mg/kg, 250mg/kg and 500mg/kg respectively while another 3 groups received Huang Lian as described previously combined with 50mg/kg of XSLJZT. The control group of mice was fed with the same volume of saline. The weights of the mice were recorded weekly while XSLJZT significantly increase the weight of the mice during the duration of 28 days. In conclusion, Huang Lian generally inhibit the Lactobacillus while has little effect on the weight of mice. 2015 Thesis NonPeerReviewed text en http://eprints.intimal.edu.my/503/1/TCM%20-%2019.pdf Chong, Janice Lee Ching (2015) Determination of Maximum Tolerated Dosage of Huang Lian in Mice and its Effect of Intestinal Lactobacillus Population. Other thesis, INTI International University.
institution INTI International University
building INTI Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider INTI International University
content_source INTI Institutional Repository
url_provider http://eprints.intimal.edu.my
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Chong, Janice Lee Ching
Determination of Maximum Tolerated Dosage of Huang Lian in Mice and its Effect of Intestinal Lactobacillus Population
description Huang Lian also known as Rhizoma Coptidis is a dried rhizome of Coptis chinensis which belonged to the Genus Coptis and family of Ranunculaceae. It is used to clear heat and dries Dampness in Traditional Chinese Medicine. Xiang Sha Liu Jun Zhi Tang is a formula decoction used to tonify the Spleen and Stomach and improve the digestive functions. Lactobacillus is an anaerobic bacterium that belonged to the order of lactic acid bacteria (LAB). It is categorized as probiotics which commercially acts as a treatment for diarrhea, indigestion, urinary tract infections and enhancing immunity. Thus the objectives of this study are to determine the maximum tolerated dosage of Huang Lian in mice and analyses its impact on Lactobacillus population with and without XSLJZT. In this experiment, 35 mice are divided into 7 groups with 5 mice each group. Three groups received Huang Lian with the dosage raging from 65mg/kg, 250mg/kg and 500mg/kg respectively while another 3 groups received Huang Lian as described previously combined with 50mg/kg of XSLJZT. The control group of mice was fed with the same volume of saline. The weights of the mice were recorded weekly while XSLJZT significantly increase the weight of the mice during the duration of 28 days. In conclusion, Huang Lian generally inhibit the Lactobacillus while has little effect on the weight of mice.
format Thesis
author Chong, Janice Lee Ching
author_facet Chong, Janice Lee Ching
author_sort Chong, Janice Lee Ching
title Determination of Maximum Tolerated Dosage of Huang Lian in Mice and its Effect of Intestinal Lactobacillus Population
title_short Determination of Maximum Tolerated Dosage of Huang Lian in Mice and its Effect of Intestinal Lactobacillus Population
title_full Determination of Maximum Tolerated Dosage of Huang Lian in Mice and its Effect of Intestinal Lactobacillus Population
title_fullStr Determination of Maximum Tolerated Dosage of Huang Lian in Mice and its Effect of Intestinal Lactobacillus Population
title_full_unstemmed Determination of Maximum Tolerated Dosage of Huang Lian in Mice and its Effect of Intestinal Lactobacillus Population
title_sort determination of maximum tolerated dosage of huang lian in mice and its effect of intestinal lactobacillus population
publishDate 2015
url http://eprints.intimal.edu.my/503/1/TCM%20-%2019.pdf
http://eprints.intimal.edu.my/503/
_version_ 1644541224431910912
score 13.211869

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