Adaptive DNA computing algorithm by using PCR and restriction enzyme

In this paper, we introduce a new adaptive DNA coinpitting algorithm by using Poiymcruse Chain Rearlion (PCR). The adaptive algorithm is designed based on Adleman-Lipton [3I paradigm of DNA computing, However, unlike the Adleman- Lipton architecture, a cutting operation has been introduced to the al...

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Main Authors: Watanabe, Shinpei, Tsuboi, Yusei, Ibrahim, Zuwairie, Yamamoto, Tsuneto, Ono, Osamu
Format: Book Section
Language:en
Published: IEEE 2004
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Online Access:http://eprints.utm.my/9792/1/ZuwairieIbrahim2004_Adaptive_dna_computing_algorithm.pdf
http://eprints.utm.my/9792/
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author Watanabe, Shinpei
Tsuboi, Yusei
Ibrahim, Zuwairie
Yamamoto, Tsuneto
Ono, Osamu
author_facet Watanabe, Shinpei
Tsuboi, Yusei
Ibrahim, Zuwairie
Yamamoto, Tsuneto
Ono, Osamu
author_sort Watanabe, Shinpei
building UTM Library
collection Institutional Repository
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
continent Asia
country Malaysia
description In this paper, we introduce a new adaptive DNA coinpitting algorithm by using Poiymcruse Chain Rearlion (PCR). The adaptive algorithm is designed based on Adleman-Lipton [3I paradigm of DNA computing, However, unlike the Adleman- Lipton architecture, a cutting operation has been introduced to the algorithm and the mechanism in which the molecules used by computation were feedback to the next cyclc was devised. Morcovcr, amplification by PCR is performed in the molecule used by feedback and a concentration difference arises in the base sequence can be used again. By doing this, the molecules which serve as a solution candidate can he narrowcd down and the optimal solution can be detected easily. From the application point of view, a simulation has been carried out on the shortest puth problem and the validity of the proposed adaptive algorithm is stated from the results of the simulation. Finally, we go on to propose applying adaptive algorithm to the chemistry experiment which used the actual DNA molecules for soiving B universal problem.
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institution Universiti Teknologi Malaysia
language en
publishDate 2004
publisher IEEE
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spelling my.utm.eprints-97922017-08-15T04:06:43Z http://eprints.utm.my/9792/ Adaptive DNA computing algorithm by using PCR and restriction enzyme Watanabe, Shinpei Tsuboi, Yusei Ibrahim, Zuwairie Yamamoto, Tsuneto Ono, Osamu TK Electrical engineering. Electronics Nuclear engineering In this paper, we introduce a new adaptive DNA coinpitting algorithm by using Poiymcruse Chain Rearlion (PCR). The adaptive algorithm is designed based on Adleman-Lipton [3I paradigm of DNA computing, However, unlike the Adleman- Lipton architecture, a cutting operation has been introduced to the algorithm and the mechanism in which the molecules used by computation were feedback to the next cyclc was devised. Morcovcr, amplification by PCR is performed in the molecule used by feedback and a concentration difference arises in the base sequence can be used again. By doing this, the molecules which serve as a solution candidate can he narrowcd down and the optimal solution can be detected easily. From the application point of view, a simulation has been carried out on the shortest puth problem and the validity of the proposed adaptive algorithm is stated from the results of the simulation. Finally, we go on to propose applying adaptive algorithm to the chemistry experiment which used the actual DNA molecules for soiving B universal problem. IEEE 2004-12-01 Book Section PeerReviewed application/pdf en http://eprints.utm.my/9792/1/ZuwairieIbrahim2004_Adaptive_dna_computing_algorithm.pdf Watanabe, Shinpei and Tsuboi, Yusei and Ibrahim, Zuwairie and Yamamoto, Tsuneto and Ono, Osamu (2004) Adaptive DNA computing algorithm by using PCR and restriction enzyme. In: 2004 Ieee Conference On Cybernetics And Intelligent Systems. IEEE Conference on Cybernetics and Intelligent Systems , 1 . IEEE, USA, pp. 262-267. ISBN 0-7803-8643-4 10.1109/ICCIS.2004.1460423
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Watanabe, Shinpei
Tsuboi, Yusei
Ibrahim, Zuwairie
Yamamoto, Tsuneto
Ono, Osamu
Adaptive DNA computing algorithm by using PCR and restriction enzyme
title Adaptive DNA computing algorithm by using PCR and restriction enzyme
title_full Adaptive DNA computing algorithm by using PCR and restriction enzyme
title_fullStr Adaptive DNA computing algorithm by using PCR and restriction enzyme
title_full_unstemmed Adaptive DNA computing algorithm by using PCR and restriction enzyme
title_short Adaptive DNA computing algorithm by using PCR and restriction enzyme
title_sort adaptive dna computing algorithm by using pcr and restriction enzyme
topic TK Electrical engineering. Electronics Nuclear engineering
url http://eprints.utm.my/9792/1/ZuwairieIbrahim2004_Adaptive_dna_computing_algorithm.pdf
http://eprints.utm.my/9792/
url_provider http://eprints.utm.my/