Experimental comparison of initial pool generation for direct-proportional length-based DNA computing

Previously, direct-proportional length-based DNA computing (DPLB-DNAC) for solving weighted graph problems such as the shortest path problem, has been proposed. After the initial pool generation, the initial pool is subjected to amplification, by polymerase chain reaction (PCR), and finally, the out...

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Main Authors: Ibrahim, Zuwairie, Muhammad, Mohd. Saufee, Tsuboi, Yusei, Ono, Osamu, Khalid, Marzuki
Format: Conference or Workshop Item
Published: 2007
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Online Access:http://eprints.utm.my/8653/
http://dx.doi.org/10.1109/TENCON.2005.301238
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author Ibrahim, Zuwairie
Muhammad, Mohd. Saufee
Tsuboi, Yusei
Ono, Osamu
Khalid, Marzuki
author_facet Ibrahim, Zuwairie
Muhammad, Mohd. Saufee
Tsuboi, Yusei
Ono, Osamu
Khalid, Marzuki
author_sort Ibrahim, Zuwairie
building UTM Library
collection Institutional Repository
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
continent Asia
country Malaysia
description Previously, direct-proportional length-based DNA computing (DPLB-DNAC) for solving weighted graph problems such as the shortest path problem, has been proposed. After the initial pool generation, the initial pool is subjected to amplification, by polymerase chain reaction (PCR), and finally, the output of the computation can be visualized by gel electrophoresis. In this paper, we give more attention to the initial pool generation of DPLB-DNAC. For this purpose, two kinds of initial pool generation methods, which are hybridization/ligation and parallel overlap assembly (POA) are evaluated. We found that both of the methods can be successfully employed to generate the initial pool generation of DPLB-DNAC, as supported by results of actual experiments. However, POA is more preferable than that of hybridization-ligation in term of population size and generation time.
format Conference or Workshop Item
id my.utm.eprints-8653
institution Universiti Teknologi Malaysia
publishDate 2007
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spelling my.utm.eprints-86532017-08-06T01:16:49Z http://eprints.utm.my/8653/ Experimental comparison of initial pool generation for direct-proportional length-based DNA computing Ibrahim, Zuwairie Muhammad, Mohd. Saufee Tsuboi, Yusei Ono, Osamu Khalid, Marzuki TK Electrical engineering. Electronics Nuclear engineering Previously, direct-proportional length-based DNA computing (DPLB-DNAC) for solving weighted graph problems such as the shortest path problem, has been proposed. After the initial pool generation, the initial pool is subjected to amplification, by polymerase chain reaction (PCR), and finally, the output of the computation can be visualized by gel electrophoresis. In this paper, we give more attention to the initial pool generation of DPLB-DNAC. For this purpose, two kinds of initial pool generation methods, which are hybridization/ligation and parallel overlap assembly (POA) are evaluated. We found that both of the methods can be successfully employed to generate the initial pool generation of DPLB-DNAC, as supported by results of actual experiments. However, POA is more preferable than that of hybridization-ligation in term of population size and generation time. 2007 Conference or Workshop Item PeerReviewed Ibrahim, Zuwairie and Muhammad, Mohd. Saufee and Tsuboi, Yusei and Ono, Osamu and Khalid, Marzuki (2007) Experimental comparison of initial pool generation for direct-proportional length-based DNA computing. In: IEEE Region 10 Annual International Conference, Proceeding/TENCON 2007, art. No. 4085068, 21-24 Nov. 2005, Melbourne, Qld.. http://dx.doi.org/10.1109/TENCON.2005.301238
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Ibrahim, Zuwairie
Muhammad, Mohd. Saufee
Tsuboi, Yusei
Ono, Osamu
Khalid, Marzuki
Experimental comparison of initial pool generation for direct-proportional length-based DNA computing
title Experimental comparison of initial pool generation for direct-proportional length-based DNA computing
title_full Experimental comparison of initial pool generation for direct-proportional length-based DNA computing
title_fullStr Experimental comparison of initial pool generation for direct-proportional length-based DNA computing
title_full_unstemmed Experimental comparison of initial pool generation for direct-proportional length-based DNA computing
title_short Experimental comparison of initial pool generation for direct-proportional length-based DNA computing
title_sort experimental comparison of initial pool generation for direct-proportional length-based dna computing
topic TK Electrical engineering. Electronics Nuclear engineering
url http://eprints.utm.my/8653/
http://dx.doi.org/10.1109/TENCON.2005.301238
url_provider http://eprints.utm.my/