Evaluation of pharmaceutical cream production debottlenecking schemes

The main objective of this work is to model and debottleneck a pharmaceutical production of an anti-allergic cream. The base case process has a minimum cycle time of 29 hours which is equivalent to 66 batches/year. Four schemes were proposed for process debottlenecking due to the anticipated increas...

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Main Authors: Tan, Jully, Foo, Dominic Chwan Yee, Kumaresan, Sivakumar, Abdul Aziz, Ramlan
Format: Conference or Workshop Item
Language:en
Published: 2005
Subjects:
Online Access:http://eprints.utm.my/5366/1/JullyTan2005_EvaluationOfPharmaceuticalCreamProduction.pdf
http://eprints.utm.my/5366/
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author Tan, Jully
Foo, Dominic Chwan Yee
Kumaresan, Sivakumar
Abdul Aziz, Ramlan
author_facet Tan, Jully
Foo, Dominic Chwan Yee
Kumaresan, Sivakumar
Abdul Aziz, Ramlan
author_sort Tan, Jully
building UTM Library
collection Institutional Repository
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
continent Asia
country Malaysia
description The main objective of this work is to model and debottleneck a pharmaceutical production of an anti-allergic cream. The base case process has a minimum cycle time of 29 hours which is equivalent to 66 batches/year. Four schemes were proposed for process debottlenecking due to the anticipated increase of the product demand of 150% in the market. By carrying out throughput analysis study, schemes that fulfil the debottlenecking objective were determined. Out of the four debottlenecking schemes, Scheme 4 was chosen, which proposed a new blending tank and intermediate tank, showed a production increase of over 150%.
format Conference or Workshop Item
id my.utm.eprints-5366
institution Universiti Teknologi Malaysia
language en
publishDate 2005
record_format eprints
spelling my.utm.eprints-53662010-06-01T15:29:45Z http://eprints.utm.my/5366/ Evaluation of pharmaceutical cream production debottlenecking schemes Tan, Jully Foo, Dominic Chwan Yee Kumaresan, Sivakumar Abdul Aziz, Ramlan T Technology (General) The main objective of this work is to model and debottleneck a pharmaceutical production of an anti-allergic cream. The base case process has a minimum cycle time of 29 hours which is equivalent to 66 batches/year. Four schemes were proposed for process debottlenecking due to the anticipated increase of the product demand of 150% in the market. By carrying out throughput analysis study, schemes that fulfil the debottlenecking objective were determined. Out of the four debottlenecking schemes, Scheme 4 was chosen, which proposed a new blending tank and intermediate tank, showed a production increase of over 150%. 2005 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.utm.my/5366/1/JullyTan2005_EvaluationOfPharmaceuticalCreamProduction.pdf Tan, Jully and Foo, Dominic Chwan Yee and Kumaresan, Sivakumar and Abdul Aziz, Ramlan (2005) Evaluation of pharmaceutical cream production debottlenecking schemes. In: International Symposium On Design, Operation and Control Of Chemical Processes 2005, 13-15 August 2005, Seoul, Korea.
spellingShingle T Technology (General)
Tan, Jully
Foo, Dominic Chwan Yee
Kumaresan, Sivakumar
Abdul Aziz, Ramlan
Evaluation of pharmaceutical cream production debottlenecking schemes
title Evaluation of pharmaceutical cream production debottlenecking schemes
title_full Evaluation of pharmaceutical cream production debottlenecking schemes
title_fullStr Evaluation of pharmaceutical cream production debottlenecking schemes
title_full_unstemmed Evaluation of pharmaceutical cream production debottlenecking schemes
title_short Evaluation of pharmaceutical cream production debottlenecking schemes
title_sort evaluation of pharmaceutical cream production debottlenecking schemes
topic T Technology (General)
url http://eprints.utm.my/5366/1/JullyTan2005_EvaluationOfPharmaceuticalCreamProduction.pdf
http://eprints.utm.my/5366/
url_provider http://eprints.utm.my/