Influence of surfactant types on correlation of retention factor and hydrophobicity of selected triazole fungicides in micellar electrokinetic chromatography
Application of micellar electrokinetic chromatography (MEKC) in quantitative structure-retention relationship (QSRR) has been studied for selected triazole fungicides. Effect of different surfactant types and concentrations of bile salts and sodium dodecyl sulfate on the correlation between logarit...
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Malaysian Society of Analytical Sciences
2008
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| Online Access: | http://eprints.utm.my/432/ http://www.ukm.my/mjas/v12_n3/Wan%20Aini%20Wan%20Ibrahim.pdf |
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| author | Wan Ibrahim, Wan Aini Hermawan, Dadan Hasan, Mohamed Noor Sanagi, Mohd. Marsin |
| author_facet | Wan Ibrahim, Wan Aini Hermawan, Dadan Hasan, Mohamed Noor Sanagi, Mohd. Marsin |
| author_sort | Wan Ibrahim, Wan Aini |
| building | UTM Library |
| collection | Institutional Repository |
| content_provider | Universiti Teknologi Malaysia |
| content_source | UTM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Application of micellar electrokinetic chromatography (MEKC) in quantitative structure-retention relationship (QSRR) has been studied for selected triazole fungicides. Effect of different surfactant types and concentrations of bile salts and sodium dodecyl sulfate on the correlation between logarithm of retention factor (log k) in MEKC and logarithm of octanol-water partition coefficient (log Pow) was investigated. Five standard fungicides (cyproconazole, bromuconazole, epoxiconazole, bitertanol and difenoconazole) with known log Pow values from 2.9 to 4.3 were used for constructing the calibration curve of log Pow against the MEKC retention factor, log k. High correlations were observed between hydrophobicity (log Pow) and log k in MEKC using two bile salt surfactants viz. sodium cholate and sodium deoxycholate and mixed bile salt systems, with squared correlation coefficient of linear regression greater than 0.98, due to the similar hydrogen bonding interaction patterns between bile salts MEKC systems and the octanol-water system. |
| format | Article |
| id | my.utm.eprints-432 |
| institution | Universiti Teknologi Malaysia |
| publishDate | 2008 |
| publisher | Malaysian Society of Analytical Sciences |
| record_format | eprints |
| spelling | my.utm.eprints-4322012-11-19T07:16:29Z http://eprints.utm.my/432/ Influence of surfactant types on correlation of retention factor and hydrophobicity of selected triazole fungicides in micellar electrokinetic chromatography Wan Ibrahim, Wan Aini Hermawan, Dadan Hasan, Mohamed Noor Sanagi, Mohd. Marsin QD Chemistry Application of micellar electrokinetic chromatography (MEKC) in quantitative structure-retention relationship (QSRR) has been studied for selected triazole fungicides. Effect of different surfactant types and concentrations of bile salts and sodium dodecyl sulfate on the correlation between logarithm of retention factor (log k) in MEKC and logarithm of octanol-water partition coefficient (log Pow) was investigated. Five standard fungicides (cyproconazole, bromuconazole, epoxiconazole, bitertanol and difenoconazole) with known log Pow values from 2.9 to 4.3 were used for constructing the calibration curve of log Pow against the MEKC retention factor, log k. High correlations were observed between hydrophobicity (log Pow) and log k in MEKC using two bile salt surfactants viz. sodium cholate and sodium deoxycholate and mixed bile salt systems, with squared correlation coefficient of linear regression greater than 0.98, due to the similar hydrogen bonding interaction patterns between bile salts MEKC systems and the octanol-water system. Malaysian Society of Analytical Sciences 2008 Article PeerReviewed Wan Ibrahim, Wan Aini and Hermawan, Dadan and Hasan, Mohamed Noor and Sanagi, Mohd. Marsin (2008) Influence of surfactant types on correlation of retention factor and hydrophobicity of selected triazole fungicides in micellar electrokinetic chromatography. The Malaysian Journal of Analytical Sciences, 9 (3). pp. 624-632. ISSN 1394-2506 http://www.ukm.my/mjas/v12_n3/Wan%20Aini%20Wan%20Ibrahim.pdf |
| spellingShingle | QD Chemistry Wan Ibrahim, Wan Aini Hermawan, Dadan Hasan, Mohamed Noor Sanagi, Mohd. Marsin Influence of surfactant types on correlation of retention factor and hydrophobicity of selected triazole fungicides in micellar electrokinetic chromatography |
| title | Influence of surfactant types on correlation of retention factor and hydrophobicity of selected triazole fungicides in micellar electrokinetic chromatography |
| title_full | Influence of surfactant types on correlation of retention factor and hydrophobicity of selected triazole fungicides in micellar electrokinetic chromatography |
| title_fullStr | Influence of surfactant types on correlation of retention factor and hydrophobicity of selected triazole fungicides in micellar electrokinetic chromatography |
| title_full_unstemmed | Influence of surfactant types on correlation of retention factor and hydrophobicity of selected triazole fungicides in micellar electrokinetic chromatography |
| title_short | Influence of surfactant types on correlation of retention factor and hydrophobicity of selected triazole fungicides in micellar electrokinetic chromatography |
| title_sort | influence of surfactant types on correlation of retention factor and hydrophobicity of selected triazole fungicides in micellar electrokinetic chromatography |
| topic | QD Chemistry |
| url | http://eprints.utm.my/432/ http://www.ukm.my/mjas/v12_n3/Wan%20Aini%20Wan%20Ibrahim.pdf |
| url_provider | http://eprints.utm.my/ |