Sodium alginate-zinc oxide nanocomposite film for antibacterial wound healing applications
This study aims to develop sodium alginate (SA) based ZnO nanoparticles as antibacterial film for wound healing applications. As natural materials, sodium alginate has been widely investigated and used in wound healing. The ZnO nanoparticles were incorporated as antibacterial into sodium alginate wi...
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| Format: | Article |
| Language: | en |
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AMG Transcend Association
2020
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| Online Access: | http://eprints.uthm.edu.my/6303/1/AJ%202020%20%28263%29.pdf http://eprints.uthm.edu.my/6303/ https://doi.org/10.33263/BRIAC105.62456252 |
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| author | Abdul Bakil, Siti Natrah Kamal, Hazirah Abdullah, Hasan Zuhudi Idris, Maizlinda Izwana |
| author_facet | Abdul Bakil, Siti Natrah Kamal, Hazirah Abdullah, Hasan Zuhudi Idris, Maizlinda Izwana |
| author_sort | Abdul Bakil, Siti Natrah |
| building | UTHM Library |
| collection | Institutional Repository |
| content_provider | Universiti Tun Hussein Onn Malaysia |
| content_source | UTHM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | This study aims to develop sodium alginate (SA) based ZnO nanoparticles as antibacterial film for wound healing applications. As natural materials, sodium alginate has been widely investigated and used in wound healing. The ZnO nanoparticles were incorporated as antibacterial into sodium alginate with different compositions (2, 4, 6, 8, 10 ml). Solvent casting method was performed to prepare a film. The film was characterized by using Fourier Transform Infrared Spectroscopy (FT-IR), Atomic Force Microscopy (AFM) and Field Emission Scanning Electron Microscopy (FESEM). Effectiveness of antibacterial activity was carried out against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) to characterize the sample. The results from microstructure analysis indicated that as ZnO nanoparticle compositions increased, the film surface became rough. It was found that sodium alginate incorporated with ZnO had slightly higher antibacterial activities against S. aureus than E. coli. Thus, sodium alginate (SA)-Zinc oxide (ZnO) nanoparticle has the potential to be used as a wound healing material in biomedical applications. |
| format | Article |
| id | my.uthm.eprints-6303 |
| institution | Universiti Tun Hussein Onn Malaysia |
| language | en |
| publishDate | 2020 |
| publisher | AMG Transcend Association |
| record_format | eprints |
| spelling | my.uthm.eprints-63032022-01-30T01:25:44Z http://eprints.uthm.edu.my/6303/ Sodium alginate-zinc oxide nanocomposite film for antibacterial wound healing applications Abdul Bakil, Siti Natrah Kamal, Hazirah Abdullah, Hasan Zuhudi Idris, Maizlinda Izwana R856-857 Biomedical engineering. Electronics. Instrumentation T Technology (General) This study aims to develop sodium alginate (SA) based ZnO nanoparticles as antibacterial film for wound healing applications. As natural materials, sodium alginate has been widely investigated and used in wound healing. The ZnO nanoparticles were incorporated as antibacterial into sodium alginate with different compositions (2, 4, 6, 8, 10 ml). Solvent casting method was performed to prepare a film. The film was characterized by using Fourier Transform Infrared Spectroscopy (FT-IR), Atomic Force Microscopy (AFM) and Field Emission Scanning Electron Microscopy (FESEM). Effectiveness of antibacterial activity was carried out against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) to characterize the sample. The results from microstructure analysis indicated that as ZnO nanoparticle compositions increased, the film surface became rough. It was found that sodium alginate incorporated with ZnO had slightly higher antibacterial activities against S. aureus than E. coli. Thus, sodium alginate (SA)-Zinc oxide (ZnO) nanoparticle has the potential to be used as a wound healing material in biomedical applications. AMG Transcend Association 2020 Article PeerReviewed text en http://eprints.uthm.edu.my/6303/1/AJ%202020%20%28263%29.pdf Abdul Bakil, Siti Natrah and Kamal, Hazirah and Abdullah, Hasan Zuhudi and Idris, Maizlinda Izwana (2020) Sodium alginate-zinc oxide nanocomposite film for antibacterial wound healing applications. Biointerface Research in Applied Chemistry, 10 (5). pp. 6245-6252. ISSN 2069-5837 https://doi.org/10.33263/BRIAC105.62456252 |
| spellingShingle | R856-857 Biomedical engineering. Electronics. Instrumentation T Technology (General) Abdul Bakil, Siti Natrah Kamal, Hazirah Abdullah, Hasan Zuhudi Idris, Maizlinda Izwana Sodium alginate-zinc oxide nanocomposite film for antibacterial wound healing applications |
| title | Sodium alginate-zinc oxide nanocomposite film for antibacterial wound healing applications |
| title_full | Sodium alginate-zinc oxide nanocomposite film for antibacterial wound healing applications |
| title_fullStr | Sodium alginate-zinc oxide nanocomposite film for antibacterial wound healing applications |
| title_full_unstemmed | Sodium alginate-zinc oxide nanocomposite film for antibacterial wound healing applications |
| title_short | Sodium alginate-zinc oxide nanocomposite film for antibacterial wound healing applications |
| title_sort | sodium alginate-zinc oxide nanocomposite film for antibacterial wound healing applications |
| topic | R856-857 Biomedical engineering. Electronics. Instrumentation T Technology (General) |
| url | http://eprints.uthm.edu.my/6303/1/AJ%202020%20%28263%29.pdf http://eprints.uthm.edu.my/6303/ https://doi.org/10.33263/BRIAC105.62456252 |
| url_provider | http://eprints.uthm.edu.my/ |