Citric acid: a green cross-linker of biomaterials for biomedical application
The application of biomaterials in biomedicine currently suffers some drawbacks, such as inflammation and immunological responses due to mismatching and/or limited compatibility. Biomaterials that are cross-linked with citric acid (CA), also called citrate-based biomaterials (CBBs), have exhibited a...
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| Format: | Article |
| Language: | en |
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Elsevier
2021
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| Online Access: | http://eprints.uthm.edu.my/6299/1/J12909_e9d2dda8f193934e03fc6cfaa21658ae.pdf http://eprints.uthm.edu.my/6299/ https://doi.org/10.1016/j.eurpolymj.2021.110271 |
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| author | Salihu, Rabiu Abd Razak, Saiful Izwan Ahmad Zawawi, Nurliyana Abdul Kadir, Mohammed Rafiq Ismail, Norjihada Izzah Mat Nayan, Nadirul Hasraf Jusoh, Norhana Mohamad, Mohd Riduan |
| author_facet | Salihu, Rabiu Abd Razak, Saiful Izwan Ahmad Zawawi, Nurliyana Abdul Kadir, Mohammed Rafiq Ismail, Norjihada Izzah Mat Nayan, Nadirul Hasraf Jusoh, Norhana Mohamad, Mohd Riduan |
| author_sort | Salihu, Rabiu |
| building | UTHM Library |
| collection | Institutional Repository |
| content_provider | Universiti Tun Hussein Onn Malaysia |
| content_source | UTHM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | The application of biomaterials in biomedicine currently suffers some drawbacks, such as inflammation and immunological responses due to mismatching and/or limited compatibility. Biomaterials that are cross-linked with citric acid (CA), also called citrate-based biomaterials (CBBs), have exhibited advanced in-vitro and in-vivo material properties that make them suitable for various biomedical applications. Tunable mechanical properties, biocompatibility, and biofunctionality are among other factors that make CBBs interesting in this field. To emphasize the safety and greenness nature of CA, in this review, we have highlighted the history, potential considerations of exploration, and a summarized stage-wise criterion for developing CBBs. We also discuss several points of view about the application of CA and CBBs in many different aspects of biomedicine, such as in tissue engineering, cancer therapy, and wound dressings. |
| format | Article |
| id | my.uthm.eprints-6299 |
| institution | Universiti Tun Hussein Onn Malaysia |
| language | en |
| publishDate | 2021 |
| publisher | Elsevier |
| record_format | eprints |
| spelling | my.uthm.eprints-62992022-01-30T01:13:52Z http://eprints.uthm.edu.my/6299/ Citric acid: a green cross-linker of biomaterials for biomedical application Salihu, Rabiu Abd Razak, Saiful Izwan Ahmad Zawawi, Nurliyana Abdul Kadir, Mohammed Rafiq Ismail, Norjihada Izzah Mat Nayan, Nadirul Hasraf Jusoh, Norhana Mohamad, Mohd Riduan R856-857 Biomedical engineering. Electronics. Instrumentation T Technology (General) The application of biomaterials in biomedicine currently suffers some drawbacks, such as inflammation and immunological responses due to mismatching and/or limited compatibility. Biomaterials that are cross-linked with citric acid (CA), also called citrate-based biomaterials (CBBs), have exhibited advanced in-vitro and in-vivo material properties that make them suitable for various biomedical applications. Tunable mechanical properties, biocompatibility, and biofunctionality are among other factors that make CBBs interesting in this field. To emphasize the safety and greenness nature of CA, in this review, we have highlighted the history, potential considerations of exploration, and a summarized stage-wise criterion for developing CBBs. We also discuss several points of view about the application of CA and CBBs in many different aspects of biomedicine, such as in tissue engineering, cancer therapy, and wound dressings. Elsevier 2021 Article PeerReviewed text en http://eprints.uthm.edu.my/6299/1/J12909_e9d2dda8f193934e03fc6cfaa21658ae.pdf Salihu, Rabiu and Abd Razak, Saiful Izwan and Ahmad Zawawi, Nurliyana and Abdul Kadir, Mohammed Rafiq and Ismail, Norjihada Izzah and Mat Nayan, Nadirul Hasraf and Jusoh, Norhana and Mohamad, Mohd Riduan (2021) Citric acid: a green cross-linker of biomaterials for biomedical application. European Polymer Journal, 146 (5). https://doi.org/10.1016/j.eurpolymj.2021.110271 |
| spellingShingle | R856-857 Biomedical engineering. Electronics. Instrumentation T Technology (General) Salihu, Rabiu Abd Razak, Saiful Izwan Ahmad Zawawi, Nurliyana Abdul Kadir, Mohammed Rafiq Ismail, Norjihada Izzah Mat Nayan, Nadirul Hasraf Jusoh, Norhana Mohamad, Mohd Riduan Citric acid: a green cross-linker of biomaterials for biomedical application |
| title | Citric acid: a green cross-linker of biomaterials for biomedical application |
| title_full | Citric acid: a green cross-linker of biomaterials for biomedical application |
| title_fullStr | Citric acid: a green cross-linker of biomaterials for biomedical application |
| title_full_unstemmed | Citric acid: a green cross-linker of biomaterials for biomedical application |
| title_short | Citric acid: a green cross-linker of biomaterials for biomedical application |
| title_sort | citric acid: a green cross-linker of biomaterials for biomedical application |
| topic | R856-857 Biomedical engineering. Electronics. Instrumentation T Technology (General) |
| url | http://eprints.uthm.edu.my/6299/1/J12909_e9d2dda8f193934e03fc6cfaa21658ae.pdf http://eprints.uthm.edu.my/6299/ https://doi.org/10.1016/j.eurpolymj.2021.110271 |
| url_provider | http://eprints.uthm.edu.my/ |