A hybrid of integer differential bees and flux balance analysis for improving succinate and lactate production
The production of succinate and lactate from E.coli become a demand in pharmaceutical industries. To increase the yield of the production, gene knockout technique was implemented in various hybrid optimization algorithms. In recent years, several hybrid optimizations have been introduced to optimize...
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| Format: | Article |
| Language: | en |
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Insight - Indonesian Society for Knowledge and Human Development
2017
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| Online Access: | http://eprints.uthm.edu.my/3331/1/AJ%202017%20%28478%29.pdf http://eprints.uthm.edu.my/3331/ |
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| author | Arieef, Mohd Fahmi Yee, Wen Choon Mohamad, Mohd Saberi Deris, Safaai Napis, Suhaimi Kasim, Shahreen |
| author_facet | Arieef, Mohd Fahmi Yee, Wen Choon Mohamad, Mohd Saberi Deris, Safaai Napis, Suhaimi Kasim, Shahreen |
| author_sort | Arieef, Mohd Fahmi |
| building | UTHM Library |
| collection | Institutional Repository |
| content_provider | Universiti Tun Hussein Onn Malaysia |
| content_source | UTHM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | The production of succinate and lactate from E.coli become a demand in pharmaceutical industries. To increase the yield of the production, gene knockout technique was implemented in various hybrid optimization algorithms. In recent years, several hybrid optimizations have been introduced to optimize succinate and lactate production. However, the previous works were ineffective to produce the highest production due to the size and complexity of metabolic networks and the dynamic interaction between the components. Therefore, the main purpose of this study is to overcome the limitation of the existing algorithms which hybridizing Integer Differential Bees and Flux Balance Analysis (IDBFBA). The experimental results show a better performance in terms of growth rate and production yield of desired phenotypes compared to the method used in previous works. |
| format | Article |
| id | my.uthm.eprints-3331 |
| institution | Universiti Tun Hussein Onn Malaysia |
| language | en |
| publishDate | 2017 |
| publisher | Insight - Indonesian Society for Knowledge and Human Development |
| record_format | eprints |
| spelling | my.uthm.eprints-33312021-11-16T07:35:36Z http://eprints.uthm.edu.my/3331/ A hybrid of integer differential bees and flux balance analysis for improving succinate and lactate production Arieef, Mohd Fahmi Yee, Wen Choon Mohamad, Mohd Saberi Deris, Safaai Napis, Suhaimi Kasim, Shahreen QP501-801 Animal biochemistry The production of succinate and lactate from E.coli become a demand in pharmaceutical industries. To increase the yield of the production, gene knockout technique was implemented in various hybrid optimization algorithms. In recent years, several hybrid optimizations have been introduced to optimize succinate and lactate production. However, the previous works were ineffective to produce the highest production due to the size and complexity of metabolic networks and the dynamic interaction between the components. Therefore, the main purpose of this study is to overcome the limitation of the existing algorithms which hybridizing Integer Differential Bees and Flux Balance Analysis (IDBFBA). The experimental results show a better performance in terms of growth rate and production yield of desired phenotypes compared to the method used in previous works. Insight - Indonesian Society for Knowledge and Human Development 2017 Article PeerReviewed text en http://eprints.uthm.edu.my/3331/1/AJ%202017%20%28478%29.pdf Arieef, Mohd Fahmi and Yee, Wen Choon and Mohamad, Mohd Saberi and Deris, Safaai and Napis, Suhaimi and Kasim, Shahreen (2017) A hybrid of integer differential bees and flux balance analysis for improving succinate and lactate production. International Journal on Advanced Science Engineering Information Technology, 7 (4-2). pp. 1615-1620. ISSN 2088-5334 |
| spellingShingle | QP501-801 Animal biochemistry Arieef, Mohd Fahmi Yee, Wen Choon Mohamad, Mohd Saberi Deris, Safaai Napis, Suhaimi Kasim, Shahreen A hybrid of integer differential bees and flux balance analysis for improving succinate and lactate production |
| title | A hybrid of integer differential bees and flux balance analysis for improving succinate and lactate production |
| title_full | A hybrid of integer differential bees and flux balance analysis for improving succinate and lactate production |
| title_fullStr | A hybrid of integer differential bees and flux balance analysis for improving succinate and lactate production |
| title_full_unstemmed | A hybrid of integer differential bees and flux balance analysis for improving succinate and lactate production |
| title_short | A hybrid of integer differential bees and flux balance analysis for improving succinate and lactate production |
| title_sort | hybrid of integer differential bees and flux balance analysis for improving succinate and lactate production |
| topic | QP501-801 Animal biochemistry |
| url | http://eprints.uthm.edu.my/3331/1/AJ%202017%20%28478%29.pdf http://eprints.uthm.edu.my/3331/ |
| url_provider | http://eprints.uthm.edu.my/ |