BSLT and DPPH Methods to Determine the Potential Toxicity of Archidendron Pauciflorum Skin to Artemia Salina and the Antioxidant Potential as an Early Exploration of Anti-Cancer Drugs
Archidendron pauciflorum skin is a dense waste that pollutes the environment and can be a problem if not properly cleaned. According to previous research, Archidendron pauciflorum skin has a very high potential because it contains flavonoid components and polyphenols with anti-cancer and antibacter...
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semarak ilmu
2025
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| Online Access: | http://eprints.uthm.edu.my/12358/1/J17768_0e7dfa4355e47b84306c8f90c31868f8.pdf http://eprints.uthm.edu.my/12358/ https://doi.org/10.37934/araset.43.1.201210 |
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| author | Surya, Alfin Abdul Rahman, Aqilah Awg Zaiyar, Zaiyar Hest Marliza, Hest Marliza |
| author_facet | Surya, Alfin Abdul Rahman, Aqilah Awg Zaiyar, Zaiyar Hest Marliza, Hest Marliza |
| author_sort | Surya, Alfin |
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| content_provider | Universiti Tun Hussein Onn Malaysia |
| content_source | UTHM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Archidendron pauciflorum skin is a dense waste that pollutes the environment and can be a problem if not properly cleaned. According to previous research, Archidendron
pauciflorum skin has a very high potential because it contains flavonoid components and polyphenols with anti-cancer and antibacterial properties. To evaluate the toxicity activity with the BSLT Method and the antioxidant DPPH Method, the scalp is cut into small pieces, dried in the oven at 60 °C, and then macerated for 24 hours in a mixture of methanol and ethyl acetate solvents as well as hexane to produce polar, semipolar, and non-polar chemicals. The fibre from each solvent is collected, and the rotary evaporator is used to evaporate it until a thick extract is produced. According to the
final findings of the study, the LC50 value (μg/mL) for each solvent is: the methanol value is 111 ppm, while ethyl acetate is 192 ppm. While for the test of antioxidant activity, significant results were obtained on the methanol solvent with an IC50 value of 51.13 μg/mL The conclusion of this study is that the 24-hour maceration period is the most efficient solvent for toxicity to Artemia salina and antioxidants to continue further research in the search for anti-cancer drugs. |
| format | Article |
| id | my.uthm.eprints-12358 |
| institution | Universiti Tun Hussein Onn Malaysia |
| language | en |
| publishDate | 2025 |
| publisher | semarak ilmu |
| record_format | eprints |
| spelling | my.uthm.eprints-123582025-05-05T04:47:25Z http://eprints.uthm.edu.my/12358/ BSLT and DPPH Methods to Determine the Potential Toxicity of Archidendron Pauciflorum Skin to Artemia Salina and the Antioxidant Potential as an Early Exploration of Anti-Cancer Drugs Surya, Alfin Abdul Rahman, Aqilah Awg Zaiyar, Zaiyar Hest Marliza, Hest Marliza QK Botany Archidendron pauciflorum skin is a dense waste that pollutes the environment and can be a problem if not properly cleaned. According to previous research, Archidendron pauciflorum skin has a very high potential because it contains flavonoid components and polyphenols with anti-cancer and antibacterial properties. To evaluate the toxicity activity with the BSLT Method and the antioxidant DPPH Method, the scalp is cut into small pieces, dried in the oven at 60 °C, and then macerated for 24 hours in a mixture of methanol and ethyl acetate solvents as well as hexane to produce polar, semipolar, and non-polar chemicals. The fibre from each solvent is collected, and the rotary evaporator is used to evaporate it until a thick extract is produced. According to the final findings of the study, the LC50 value (μg/mL) for each solvent is: the methanol value is 111 ppm, while ethyl acetate is 192 ppm. While for the test of antioxidant activity, significant results were obtained on the methanol solvent with an IC50 value of 51.13 μg/mL The conclusion of this study is that the 24-hour maceration period is the most efficient solvent for toxicity to Artemia salina and antioxidants to continue further research in the search for anti-cancer drugs. semarak ilmu 2025 Article PeerReviewed text en http://eprints.uthm.edu.my/12358/1/J17768_0e7dfa4355e47b84306c8f90c31868f8.pdf Surya, Alfin and Abdul Rahman, Aqilah Awg and Zaiyar, Zaiyar and Hest Marliza, Hest Marliza (2025) BSLT and DPPH Methods to Determine the Potential Toxicity of Archidendron Pauciflorum Skin to Artemia Salina and the Antioxidant Potential as an Early Exploration of Anti-Cancer Drugs. Journal of Advanced Research in Applied Sciences and Engineering Technology, 43 (1). pp. 201-210. ISSN 2462-1943 https://doi.org/10.37934/araset.43.1.201210 |
| spellingShingle | QK Botany Surya, Alfin Abdul Rahman, Aqilah Awg Zaiyar, Zaiyar Hest Marliza, Hest Marliza BSLT and DPPH Methods to Determine the Potential Toxicity of Archidendron Pauciflorum Skin to Artemia Salina and the Antioxidant Potential as an Early Exploration of Anti-Cancer Drugs |
| title | BSLT and DPPH Methods to Determine the Potential Toxicity of Archidendron Pauciflorum Skin to Artemia Salina and the Antioxidant Potential as an Early Exploration of Anti-Cancer Drugs |
| title_full | BSLT and DPPH Methods to Determine the Potential Toxicity of Archidendron Pauciflorum Skin to Artemia Salina and the Antioxidant Potential as an Early Exploration of Anti-Cancer Drugs |
| title_fullStr | BSLT and DPPH Methods to Determine the Potential Toxicity of Archidendron Pauciflorum Skin to Artemia Salina and the Antioxidant Potential as an Early Exploration of Anti-Cancer Drugs |
| title_full_unstemmed | BSLT and DPPH Methods to Determine the Potential Toxicity of Archidendron Pauciflorum Skin to Artemia Salina and the Antioxidant Potential as an Early Exploration of Anti-Cancer Drugs |
| title_short | BSLT and DPPH Methods to Determine the Potential Toxicity of Archidendron Pauciflorum Skin to Artemia Salina and the Antioxidant Potential as an Early Exploration of Anti-Cancer Drugs |
| title_sort | bslt and dpph methods to determine the potential toxicity of archidendron pauciflorum skin to artemia salina and the antioxidant potential as an early exploration of anti-cancer drugs |
| topic | QK Botany |
| url | http://eprints.uthm.edu.my/12358/1/J17768_0e7dfa4355e47b84306c8f90c31868f8.pdf http://eprints.uthm.edu.my/12358/ https://doi.org/10.37934/araset.43.1.201210 |
| url_provider | http://eprints.uthm.edu.my/ |