Development of a CAD system for stroke diagnosis using machine learning on DWI-MRI images

Stroke remains one of the leading causes of disability and mortality worldwide, necessitating timely and accurate diagnosis to improve treatment outcomes. This study presents a computer-aided diagnosis (CAD) system designed to detect and classify stroke lesions in magnetic resonance imaging (MRI),...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohd Saad, Norhashimah, Azman, Izzatul Husna, Abdullah, Abdul Rahim, Hamzah, Rostam Affendi, Muda, Ahmad Sobri, Yamba, Farzanah Atikah
Format: Article
Language:en
Published: Accent Social and Welfare Society 2025
Online Access:http://eprints.utem.edu.my/id/eprint/29556/2/00332220920251135222149.pdf
http://eprints.utem.edu.my/id/eprint/29556/
https://accentsjournals.org/PaperDirectory/Journal/IJATEE/2025/8/5.pdf
http://dx.doi.org/10.19101/IJATEE.2024.111102264
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1858062978832662528
author Mohd Saad, Norhashimah
Azman, Izzatul Husna
Abdullah, Abdul Rahim
Hamzah, Rostam Affendi
Muda, Ahmad Sobri
Yamba, Farzanah Atikah
author_facet Mohd Saad, Norhashimah
Azman, Izzatul Husna
Abdullah, Abdul Rahim
Hamzah, Rostam Affendi
Muda, Ahmad Sobri
Yamba, Farzanah Atikah
author_sort Mohd Saad, Norhashimah
building UTEM Library
collection Institutional Repository
content_provider Universiti Teknikal Malaysia Melaka
content_source UTEM Institutional Repository
continent Asia
country Malaysia
description Stroke remains one of the leading causes of disability and mortality worldwide, necessitating timely and accurate diagnosis to improve treatment outcomes. This study presents a computer-aided diagnosis (CAD) system designed to detect and classify stroke lesions in magnetic resonance imaging (MRI), specifically utilizing diffusion-weighted imaging (DWI) sequences. A hybrid segmentation technique, fuzzy c-means with active contour (FCMAC), is proposed to enhance lesion localization accuracy. For classification, the system evaluates traditional machine learning algorithms like support vector machine (SVM) and k-nearest neighbor (KNN), alongside deep learning models such as convolutional neural network (CNN) and bilayered neural network (BNN). The entire diagnostic pipeline is integrated into a MATLAB-based graphical user interface (GUI), facilitating real-time analysis and ease of use in clinical settings. Experimental results show that the proposed FCMAC method achieves a dice coefficient (DC) of 0.654, outperforming conventional segmentation techniques. Among the classifiers, KNN offered the best balance between prediction accuracy and computational efficiency. The final system, termed SmartStroke-Pro, enables early detection and classification of stroke, providing a reliable and practical tool to assist healthcare professionals, particularly in resource-limited environments. This framework has the potential to reduce diagnostic delays and support improved clinical decision-making in acute stroke care.
format Article
id my.utem.eprints-29556
institution Universiti Teknikal Malaysia Melaka
language en
publishDate 2025
publisher Accent Social and Welfare Society
record_format eprints
spelling my.utem.eprints-295562026-02-23T04:44:52Z http://eprints.utem.edu.my/id/eprint/29556/ Development of a CAD system for stroke diagnosis using machine learning on DWI-MRI images Mohd Saad, Norhashimah Azman, Izzatul Husna Abdullah, Abdul Rahim Hamzah, Rostam Affendi Muda, Ahmad Sobri Yamba, Farzanah Atikah Stroke remains one of the leading causes of disability and mortality worldwide, necessitating timely and accurate diagnosis to improve treatment outcomes. This study presents a computer-aided diagnosis (CAD) system designed to detect and classify stroke lesions in magnetic resonance imaging (MRI), specifically utilizing diffusion-weighted imaging (DWI) sequences. A hybrid segmentation technique, fuzzy c-means with active contour (FCMAC), is proposed to enhance lesion localization accuracy. For classification, the system evaluates traditional machine learning algorithms like support vector machine (SVM) and k-nearest neighbor (KNN), alongside deep learning models such as convolutional neural network (CNN) and bilayered neural network (BNN). The entire diagnostic pipeline is integrated into a MATLAB-based graphical user interface (GUI), facilitating real-time analysis and ease of use in clinical settings. Experimental results show that the proposed FCMAC method achieves a dice coefficient (DC) of 0.654, outperforming conventional segmentation techniques. Among the classifiers, KNN offered the best balance between prediction accuracy and computational efficiency. The final system, termed SmartStroke-Pro, enables early detection and classification of stroke, providing a reliable and practical tool to assist healthcare professionals, particularly in resource-limited environments. This framework has the potential to reduce diagnostic delays and support improved clinical decision-making in acute stroke care. Accent Social and Welfare Society 2025 Article PeerReviewed text en cc_by_4 http://eprints.utem.edu.my/id/eprint/29556/2/00332220920251135222149.pdf Mohd Saad, Norhashimah and Azman, Izzatul Husna and Abdullah, Abdul Rahim and Hamzah, Rostam Affendi and Muda, Ahmad Sobri and Yamba, Farzanah Atikah (2025) Development of a CAD system for stroke diagnosis using machine learning on DWI-MRI images. International Journal of Advanced Technology and Engineering Exploration, 12 (129). pp. 1246-1263. ISSN 2394-7454 https://accentsjournals.org/PaperDirectory/Journal/IJATEE/2025/8/5.pdf http://dx.doi.org/10.19101/IJATEE.2024.111102264
spellingShingle Mohd Saad, Norhashimah
Azman, Izzatul Husna
Abdullah, Abdul Rahim
Hamzah, Rostam Affendi
Muda, Ahmad Sobri
Yamba, Farzanah Atikah
Development of a CAD system for stroke diagnosis using machine learning on DWI-MRI images
title Development of a CAD system for stroke diagnosis using machine learning on DWI-MRI images
title_full Development of a CAD system for stroke diagnosis using machine learning on DWI-MRI images
title_fullStr Development of a CAD system for stroke diagnosis using machine learning on DWI-MRI images
title_full_unstemmed Development of a CAD system for stroke diagnosis using machine learning on DWI-MRI images
title_short Development of a CAD system for stroke diagnosis using machine learning on DWI-MRI images
title_sort development of a cad system for stroke diagnosis using machine learning on dwi-mri images
url http://eprints.utem.edu.my/id/eprint/29556/2/00332220920251135222149.pdf
http://eprints.utem.edu.my/id/eprint/29556/
https://accentsjournals.org/PaperDirectory/Journal/IJATEE/2025/8/5.pdf
http://dx.doi.org/10.19101/IJATEE.2024.111102264
url_provider http://eprints.utem.edu.my/