Physicochemical properties of a novel experimental alginic acid-enhanced bioceramic-based root canal sealer: A comparative in vitro evaluation

Aims: This study aims to evaluate the physicochemical properties of a new experimental alginic acid-incorporated bioceramic-based sealer (Bio-G) compared to commercialized BioRoot RCS. Materials and Methods: Bio-G sealers with 0%, 3%, and 5% alginic acid concentrations were formulated and tested for...

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Main Authors: Sim, Galvin Siang Lin, Appu, Tharani Elancovan, Baskaran, Vasunthra, Goh, Valentina Pui Nee, Tee, Yu Jie, Wong, Qiao Wen, Muhamad Halil, Mohd Haikal, Noorani, Tahir Yusuf, Abd Aziz, Mohd Syafiq
Format: Article
Language:en
Published: Wolters Kluwer Medknow Publications 2025
Online Access:http://eprints.utem.edu.my/id/eprint/29409/2/02669261220251559352796.pdf
http://eprints.utem.edu.my/id/eprint/29409/
https://journals.lww.com/jcde/fulltext/2025/07000/physicochemical_properties_of_a_novel_experimental.11.aspx
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Summary:Aims: This study aims to evaluate the physicochemical properties of a new experimental alginic acid-incorporated bioceramic-based sealer (Bio-G) compared to commercialized BioRoot RCS. Materials and Methods: Bio-G sealers with 0%, 3%, and 5% alginic acid concentrations were formulated and tested for flowability, film thickness, radiopacity, working time, setting time, solubility, dimensional stability, and pH. Standardized methodological methods were used and statistical analysis was performed using the one-way ANOVA with post hoc Tukey's HSD. Results: All Bio-G sealer groups met standards for flow (>20 mm) and film thickness (<50 μm). Bio-G (0%-algin) exhibited the highest flow, solubility, and longest setting time, while Bio-G (3%-algin) and Bio-G (5%-algin) had comparable solubility with BioRoot RCS. Radiopacity was lower in all Bio-G sealers than in BioRoot RCS but exceeded the required minimum standard. Moreover, all Bio-G sealer groups maintained an alkaline pH. Conclusion: The incorporation of alginic acid influenced the physicochemical properties of Bio-G sealers, supporting their potential as alternative bioceramic materials for endodontic applications. © 2025 Journal of Conservative Dentistry and Endodontics.