Evaluation of mandibular advancement surgery efficacy in treating obstructive sleep apnea: A study on turbulence kinetic energy
Background and Objective: Obstructive sleep apnoea (OSA) is a prevalent sleep disease characterised by recurrent airway obstruction during sleep, resulting in diminished oxygen intake and disrupted sleep patterns. This study investigates the effectiveness of mandibular advancement surgery as a surgi...
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| Language: | en |
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Elsevier Ireland Ltd
2025
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| Online Access: | http://eprints.utem.edu.my/id/eprint/28603/2/0182907022025113211652.pdf http://eprints.utem.edu.my/id/eprint/28603/ https://www.sciencedirect.com/science/article/abs/pii/S0169260725000276 |
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| author | Nik Ghazali, Nik Nazri Badruddin, Irfan Anjum Rozali, Shaifulazuar Abdul Latif, Mohd Faruq Kamangar, Sarfaraz |
| author_facet | Nik Ghazali, Nik Nazri Badruddin, Irfan Anjum Rozali, Shaifulazuar Abdul Latif, Mohd Faruq Kamangar, Sarfaraz |
| author_sort | Nik Ghazali, Nik Nazri |
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| content_provider | Universiti Teknikal Malaysia Melaka |
| content_source | UTEM Institutional Repository |
| continent | Asia |
| country | Malaysia |
| description | Background and Objective: Obstructive sleep apnoea (OSA) is a prevalent sleep disease characterised by recurrent airway obstruction during sleep, resulting in diminished oxygen intake and disrupted sleep patterns. This study investigates the effectiveness of mandibular advancement surgery as a surgical intervention for obstructive sleep apnoea by analysing the postoperative alterations in turbulence kinetic energy (TKE). Methodology: The research involved five subjects receiving mandibular advancement surgery (MAS). The quantification of TKE was performed both before and throughout the method using a combination of computational fluid dynamics (CFD) models and empirical measurements. A suitable grid size of 2.6 million cells for CFD simulations was determined by grid sensitivity analysis and corroborated with physical measurements. Results: The findings indicated a significant increase in TKE for each individual post-procedure, with increments varying from 23 % to 460 %. The elevated TKE indicates a more rapid airflow in the upper airway post-surgery. This is probably attributable to alterations in the airway's morphology resulting from the surgery. The observed rise in speed and turbulence is theoretically supported by Bernoulli's principle, which elucidates the relationship between air flow velocity and the pressure it generates. Conclusions: This study demonstrates that mandibular advancement surgery efficiently alleviates OSA by markedly enhancing airflow and diminishing turbulence in the upper airway post-treatment. The use of physical validation and grid sensitivity analysis in computational fluid dynamics simulations underscores the meticulous technique utilised, offering a comprehensive assessment of the efficacy of the surgical interventions for OSA. |
| format | Article |
| id | my.utem.eprints-28603 |
| institution | Universiti Teknikal Malaysia Melaka |
| language | en |
| publishDate | 2025 |
| publisher | Elsevier Ireland Ltd |
| record_format | eprints |
| spelling | my.utem.eprints-286032025-04-09T16:02:23Z http://eprints.utem.edu.my/id/eprint/28603/ Evaluation of mandibular advancement surgery efficacy in treating obstructive sleep apnea: A study on turbulence kinetic energy Nik Ghazali, Nik Nazri Badruddin, Irfan Anjum Rozali, Shaifulazuar Abdul Latif, Mohd Faruq Kamangar, Sarfaraz Background and Objective: Obstructive sleep apnoea (OSA) is a prevalent sleep disease characterised by recurrent airway obstruction during sleep, resulting in diminished oxygen intake and disrupted sleep patterns. This study investigates the effectiveness of mandibular advancement surgery as a surgical intervention for obstructive sleep apnoea by analysing the postoperative alterations in turbulence kinetic energy (TKE). Methodology: The research involved five subjects receiving mandibular advancement surgery (MAS). The quantification of TKE was performed both before and throughout the method using a combination of computational fluid dynamics (CFD) models and empirical measurements. A suitable grid size of 2.6 million cells for CFD simulations was determined by grid sensitivity analysis and corroborated with physical measurements. Results: The findings indicated a significant increase in TKE for each individual post-procedure, with increments varying from 23 % to 460 %. The elevated TKE indicates a more rapid airflow in the upper airway post-surgery. This is probably attributable to alterations in the airway's morphology resulting from the surgery. The observed rise in speed and turbulence is theoretically supported by Bernoulli's principle, which elucidates the relationship between air flow velocity and the pressure it generates. Conclusions: This study demonstrates that mandibular advancement surgery efficiently alleviates OSA by markedly enhancing airflow and diminishing turbulence in the upper airway post-treatment. The use of physical validation and grid sensitivity analysis in computational fluid dynamics simulations underscores the meticulous technique utilised, offering a comprehensive assessment of the efficacy of the surgical interventions for OSA. Elsevier Ireland Ltd 2025-01 Article PeerReviewed text en cc_by_nc_nd_4 http://eprints.utem.edu.my/id/eprint/28603/2/0182907022025113211652.pdf Nik Ghazali, Nik Nazri and Badruddin, Irfan Anjum and Rozali, Shaifulazuar and Abdul Latif, Mohd Faruq and Kamangar, Sarfaraz (2025) Evaluation of mandibular advancement surgery efficacy in treating obstructive sleep apnea: A study on turbulence kinetic energy. Computer Methods and Programs in Biomedicine, 261. pp. 1-21. ISSN 0169-2607 https://www.sciencedirect.com/science/article/abs/pii/S0169260725000276 10.1016/j.cmpb.2025.108610 |
| spellingShingle | Nik Ghazali, Nik Nazri Badruddin, Irfan Anjum Rozali, Shaifulazuar Abdul Latif, Mohd Faruq Kamangar, Sarfaraz Evaluation of mandibular advancement surgery efficacy in treating obstructive sleep apnea: A study on turbulence kinetic energy |
| title | Evaluation of mandibular advancement surgery efficacy in treating obstructive sleep apnea: A study on turbulence kinetic energy |
| title_full | Evaluation of mandibular advancement surgery efficacy in treating obstructive sleep apnea: A study on turbulence kinetic energy |
| title_fullStr | Evaluation of mandibular advancement surgery efficacy in treating obstructive sleep apnea: A study on turbulence kinetic energy |
| title_full_unstemmed | Evaluation of mandibular advancement surgery efficacy in treating obstructive sleep apnea: A study on turbulence kinetic energy |
| title_short | Evaluation of mandibular advancement surgery efficacy in treating obstructive sleep apnea: A study on turbulence kinetic energy |
| title_sort | evaluation of mandibular advancement surgery efficacy in treating obstructive sleep apnea: a study on turbulence kinetic energy |
| url | http://eprints.utem.edu.my/id/eprint/28603/2/0182907022025113211652.pdf http://eprints.utem.edu.my/id/eprint/28603/ https://www.sciencedirect.com/science/article/abs/pii/S0169260725000276 |
| url_provider | http://eprints.utem.edu.my/ |