The effect of 660nm light-emitting diode irradiation on human gingival fibroblast cell proliferation

Light therapy has become a common treatment modality in various medical fields, including dermatology, dentistry, and cosmetics. This study aimed to evaluate the effect of 660 nm ligh-emitting diode on the proliferation and viability of human gingival fibroblasts in vitro. The cells were irradiat...

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Main Author: JiaQi, Wang
Format: Monograph
Language:en
Published: Universiti Sains Malaysia 2025
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Online Access:http://eprints.usm.my/63404/1/Wang%20JiaQi-E.pdf
http://eprints.usm.my/63404/
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author JiaQi, Wang
author_facet JiaQi, Wang
author_sort JiaQi, Wang
building Hamzah Sendut Library
collection Institutional Repository
content_provider Universiti Sains Malaysia
content_source USM Institutional Repository
continent Asia
country Malaysia
description Light therapy has become a common treatment modality in various medical fields, including dermatology, dentistry, and cosmetics. This study aimed to evaluate the effect of 660 nm ligh-emitting diode on the proliferation and viability of human gingival fibroblasts in vitro. The cells were irradiated with 660nm light-emitting diode for 60 and 120 seconds 24-hours post-seeding. After 24- and 48-hours irradiation, cell count, and viability were determined. The results then were analysed using a one-way ANOVA test (p < 0.05). The findings revealed a significant increase in cell proliferation rate and viability in the irradiated groups compared to the control group, with the 120 seconds irradiation group showing the highest enhancement at both time points. These results suggest that 660 nm LED light can effectively promote the proliferation and viability of human gingival fibroblasts, highlighting its potential as a valuable tool in regenerative dentistry and periodontal therapy
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institution Universiti Sains Malaysia
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publisher Universiti Sains Malaysia
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spelling my.usm.eprints.63404 http://eprints.usm.my/63404/ The effect of 660nm light-emitting diode irradiation on human gingival fibroblast cell proliferation JiaQi, Wang R Medicine RA440-440.87 Study and teaching. Research Light therapy has become a common treatment modality in various medical fields, including dermatology, dentistry, and cosmetics. This study aimed to evaluate the effect of 660 nm ligh-emitting diode on the proliferation and viability of human gingival fibroblasts in vitro. The cells were irradiated with 660nm light-emitting diode for 60 and 120 seconds 24-hours post-seeding. After 24- and 48-hours irradiation, cell count, and viability were determined. The results then were analysed using a one-way ANOVA test (p < 0.05). The findings revealed a significant increase in cell proliferation rate and viability in the irradiated groups compared to the control group, with the 120 seconds irradiation group showing the highest enhancement at both time points. These results suggest that 660 nm LED light can effectively promote the proliferation and viability of human gingival fibroblasts, highlighting its potential as a valuable tool in regenerative dentistry and periodontal therapy Universiti Sains Malaysia 2025-01 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/63404/1/Wang%20JiaQi-E.pdf JiaQi, Wang (2025) The effect of 660nm light-emitting diode irradiation on human gingival fibroblast cell proliferation. Project Report. Universiti Sains Malaysia. (Submitted)
spellingShingle R Medicine
RA440-440.87 Study and teaching. Research
JiaQi, Wang
The effect of 660nm light-emitting diode irradiation on human gingival fibroblast cell proliferation
title The effect of 660nm light-emitting diode irradiation on human gingival fibroblast cell proliferation
title_full The effect of 660nm light-emitting diode irradiation on human gingival fibroblast cell proliferation
title_fullStr The effect of 660nm light-emitting diode irradiation on human gingival fibroblast cell proliferation
title_full_unstemmed The effect of 660nm light-emitting diode irradiation on human gingival fibroblast cell proliferation
title_short The effect of 660nm light-emitting diode irradiation on human gingival fibroblast cell proliferation
title_sort effect of 660nm light-emitting diode irradiation on human gingival fibroblast cell proliferation
topic R Medicine
RA440-440.87 Study and teaching. Research
url http://eprints.usm.my/63404/1/Wang%20JiaQi-E.pdf
http://eprints.usm.my/63404/
url_provider http://eprints.usm.my/